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CompletedNCT02212340Updated Sep 27, 2016

Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40 in Vitrectomy

An interventional study of fresofol and remifentanil and desflurane and remifentanil in Vitrectomy Operation Under General Anesthesia, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2016-09-27.

Sponsored by Yonsei University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
84
Allocation
Randomized
Ages
20 Years to 80 Years
Sex
All
01

Study summary

Total intravenous anesthesia (TIVA) and inhalation anesthesia are both widely and safely used, and there are many clinical trials comparing these on various aspects of anesthesia. However, there have not been studies comparing the quality of recovery from the different methods of general anesthesia in vitrectomy. In this study, the investigators compare the functional recovery after general anesthesia in TIVA and inhalation anesthesia with QoR-40 questionnaire in vitrectomy.

02

Conditions studied

  • Vitrectomy Operation Under General Anesthesia

Keywords

  • propofol
  • desflurane
  • quality of recovery
  • vitrectomy
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In context

Lead sponsor

Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
20 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Patients (20-80 years old) scheduled for vitrectomy surgery undergoing general anesthesia.
  2. ASA 1-3

Exclusion criteria

Exclusion Criteria:

  1. Patients with allergy to anesthetic agents
  2. Anticipated difficult airway
  3. BMI > 30 kg/m2
  4. Chronic obstructive pulmonary disease
  5. Heart failure 6. Unstable angina
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
84 participants (actual)

Study arms

  • Experimental
    TIVA group

    Anesthesia is maintained with fresofol and remifentanil

    Drug: fresofol and remifentanil

  • Active comparator
    Des group

    Anesthesia is maintained with desflurane and remifentanil

    Drug: desflurane and remifentanil

Interventions

  • Drugfresofol and remifentanil

    Anesthesia is maintained with fresofol and remifentanil in TIVA group or with desflurane and remifentanil in Des group according to randomly allocated group.

  • Drugdesflurane and remifentanil

    Anesthesia is maintained with fresofol and remifentanil in TIVA group or with desflurane and remifentanil in Des group according to randomly allocated group.

06

What researchers measure

Primary outcomes

  1. QoR-40 score

    Time frame: at 6 hours later after surgery

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Study locations

1 site
  • Gangnam Severance Hospital, Yonsei University College of Medicine
    Seoul, 120-752, Korea, Republic of
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 27, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02212340
Lead sponsor
Yonsei University
Responsible party
Sponsor
First posted
Aug 8, 2014
Start date
Jul 2014
Primary completion
Jan 2016
Completion
Mar 2016
Last update
Sep 27, 2016

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.

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