Hydroxymethylglutaryl-CoA Reductase Inhibitors: all 1,670 studies that test it

Page 3 of 17. Open to participants first (137), then studies with results posted, then the rest; newest registration first within each.

• Self-Assessment Method for Statin Side-effects Or NoceboCompletedNCT02668016Phase 4Results posted
• Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X SyndromeCompletedNCT02642653Phase 4Results posted
• Atorvastatin Treatment of Cavernous Angiomas With Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) TrialCompletedNCT02603328Phase 1/2Results posted
• DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)CompletedNCT02574845Phase 1Results posted
• Pharmacological Treatment of Rett Syndrome With StatinsCompletedNCT02563860Phase 2Results posted
• A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383)CompletedNCT02550288Phase 3Results posted
• A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical AtherosclerosisCompletedNCT02546323Phase 3Results posted
• Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)CompletedNCT02476006Phase 3Results posted
• A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384)CompletedNCT02460159Phase 3Results posted
• Effects of Pitavastatin on Lipid Profiles in HIV-infected Patients With Dyslipidemia and Receiving Atazanavir/RitonavirCompletedNCT02442700Phase 4Results posted
• Relationship Between Insulin Resistance and Statin Induced Type 2 Diabetes, and Integrative Personal Omics ProfilingCompletedNCT02437084Phase 4Results posted
• A Study to Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial HypercholesterolemiaCompletedNCT02434497Phase 3Results posted
• Efficacy of Atorvastatin as Adjunctive Treatment for Chronic Plaque Type PsoriasisCompletedNCT02432040Phase 2Results posted
• Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse SclerodermaCompletedNCT02370784Phase 2Results posted
• Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected AdultsCompletedNCT02344290Phase 3Results posted
• Effect of Atorvastatin on Bone-vascular AxisCompletedNCT02342015Phase 4Results posted
• Statin Use in Patients With Acute VTETerminatedNCT02331095Early Phase 1Results posted
• Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung CancerCompletedNCT02317016Phase 1Results posted
• Effects of Simvastatin and Ezetimibe on Cardiovascular Risk Markers in Patients With DyslipidemiaCompletedNCT02304926Not applicableResults posted
• A Study of LY2623091 in Healthy ParticipantsCompletedNCT02300259Phase 1Results posted
• Effects of Pitavastatin on Insulin Sensitivity and Liver FatCompletedNCT02290106Not applicableResults posted
• A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial HypercholesterolemiaCompletedNCT02226198Phase 3Results posted
• Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLCCompletedNCT02197234Phase 1Results posted
• Pilot Study of Atorvastatin for Orthopedic Surgery PatientsCompletedNCT02197065Phase 2Results posted
• Effects on Lipoprotein Metabolism From PCSK9 Inhibition Utilizing a Monoclonal AntibodyCompletedNCT02189837Phase 3Results posted
• Fixed Dose Intervention Trial of New England Enhancing Survival in SMI PatientsCompletedNCT02188121Phase 4Results posted
• A Study of Evacetrapib With Selected Statins in Healthy Chinese ParticipantsCompletedNCT02156492Phase 1Results posted
• The Effect of Atorvastatin on Endothelial Cell Dysfunction in Chronic Kidney DiseaseTerminatedNCT02133534Phase 4Results posted
• Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance ImagingTerminatedNCT02114697Phase 4Results posted
• Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent SimvastatinTerminatedNCT02096588Phase 2Results posted
• A Phase 1 Study to Evaluate the Effects of Fluconazole and Atorvastatin on the Pharmacokinetics of TAK-385 in Healthy SubjectsCompletedNCT02093390Phase 1Results posted
• Atrovastatin for Preventing Atrial Fibrillation Following Open Cardiac Valve RepairCompletedNCT02084069Phase 3Results posted
• Elite Controller and ART-treated HIV+ Statin Versus ASA Treatment Intervention StudyCompletedNCT02081638Phase 2Results posted
• Evaluate the Effect of Atorvastatin on the Pharmacokinetics of Lomitapide in Healthy Subjects.CompletedNCT02080455Phase 1Results posted
• Safety of Simvastatin in LAM and TSCCompletedNCT02061397Phase 1/2Results posted
• Statin Therapy in Acute InfluenzaCompletedNCT02056340Phase 2Results posted
• Effect of Vitamin D Supplementation on Exercise Adaptations in Patients on Statin TherapyCompletedNCT02030041Phase 3Results posted
• Preventing Anthracycline Cardiovascular Toxicity With Statins (PREVENT)CompletedNCT01988571Phase 2Results posted
• Effect of SSP-004184 (SPD602) on the Pharmacokinetics of Simvastatin in Healthy Adult SubjectsCompletedNCT01979185Phase 1Results posted
• Neuroprotection With Statin Therapy for Acute Recovery Trial Phase 2CompletedNCT01976936Phase 2Results posted
• Actual Use Trial of Atorvastatin Calcium 10 mgCompletedNCT01964326Phase 3Results posted
• A Study of Baricitinib and Simvastatin in Healthy ParticipantsCompletedNCT01960140Phase 1Results posted
• A Study of Evacetrapib in Japanese and Non-Japanese ParticipantsCompletedNCT01958489Phase 1Results posted
• Simvastatin for mTBICompletedNCT01952288Phase 4Results posted
• Efficacy and Safety of Valsartan 160mg and Rosuvastatin 20mg in Patients With Hypertension and HyperlipidemiaCompletedNCT01918332Phase 3Results posted
• YELLOW II Study: Reduction in Coronary Yellow Plaque, Lipids and Vascular Inflammation by Aggressive Lipid LoweringCompletedNCT01837823Phase 2Results posted
• Risk Factor Control Before Orthopedic SurgeryTerminatedNCT01837069Phase 4Results posted
• Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromesCompletedNCT01831232Not applicableResults posted
• Does Rosuvastatin Delay Progression of Atherosclerosis in HIVCompletedNCT01813357Phase 4Results posted
• Investigation of Interactions Between Faldaprevir, Itraconazole, Atorvastatin and RosuvastatinCompletedNCT01795937Phase 1Results posted
• Prothrombotic Inflammatory Markers in Women With Metabolic Syndrome - Effect of AtorvastatinCompletedNCT01785615Phase 1/2Results posted
• Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic AcidTerminatedNCT01772719Not applicableResults posted
• LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2CompletedNCT01763866Phase 3Results posted
• Statin Therapy in Young Adult Survivors of Childhood CancerCompletedNCT01733953Phase 2Results posted
• Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell DiseaseCompletedNCT01732718Phase 2Results posted
• Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)CompletedNCT01730040Phase 3Results posted
• Efficacy and Safety Study of Pitavastatin for HypercholesterolemiaCompletedNCT01710007Phase 3Results posted
• Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell DiseaseCompletedNCT01702246Phase 1/2Results posted
• Exercise, Statins, and the Metabolic SyndromeCompletedNCT01700530Not applicableResults posted
• Pharmacokinetic Study of Pitavastatin and Ritonavir-Boosted Darunavir or EfavirenzCompletedNCT01695954Phase 1Results posted
• A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)TerminatedNCT01678820Phase 3Results posted
• A 12-week Study to Compare the Efficacy and Safety of Fixed Combinations of Fenofibrate/Simvastatin 145/20mg and Fenofibrate/Simvastatin 145/40mg Tablets Versus Fenofibrate or Simvastatin Monotherapies in Subjects With Abnormal Blood Levels of Fats (Lipids) and at High Risk of Cardiovascular DiseaseCompletedNCT01674712Phase 3Results posted
• Simvastatin Augmentation of Lithium Treatment in Bipolar DepressionTerminatedNCT01665950Phase 2Results posted
• Atorvastatin as GVHD Prophylaxis for Allogeneic Hematopoietic Cell TransplantationCompletedNCT01665677Phase 2Results posted
• A Study Comparing CoQ10 Levels While Taking 3 Different StatinsCompletedNCT01660191Phase 4Results posted
• Hydroxychloroquine/Atorvastatin in the Treatment of Osteoarthritis (OA) of the KneeCompletedNCT01645176Phase 2Results posted
• Downmodulating Monocyte Activation for HIV-1 Associated Neurocognitive Disorders (HAND)CompletedNCT01600170Phase 4Results posted
• Reduction in YEllow Plaque by Aggressive Lipid LOWering TherapyCompletedNCT01567826Phase 4Results posted
• Efficacy and Safety of Fluvastatin Sodium Extended Release Tablets 80 mg Once Daily in Chinese Patients With Primary Hypercholesterolemia or Mixed DyslipidemiaCompletedNCT01551173Phase 4Results posted
• LIpid Lowering With Highly Potent Statins in Hyperlipidaemia With Type 2 Diabetes patiENtsCompletedNCT01544309Not applicableResults posted
• Aggressive Cholesterol Therapy to Inhibit Vein Graft Events After CABG (ACTIVE Trial)CompletedNCT01528709Phase 3Results posted
• Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological MalignanciesCompletedNCT01527045Phase 2Results posted
• Donor Atorvastatin Treatment for Preventing Severe Acute Graft-Versus-Host Disease in Patients Undergoing Myeloablative Peripheral Blood Stem Cell TransplantationCompletedNCT01525407Phase 2Results posted
• Clinical Trial of Simvastatin to Treat Generalized VitiligoCompletedNCT01517893Phase 2Results posted
• Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell TransplantationCompletedNCT01491958Phase 2Results posted
• Pre-Prostatectomy Lovastatin on Prostate CancerTerminatedNCT01478828Not applicableResults posted
• Endothelial Facilitation in Alzheimer's DiseaseCompletedNCT01439555Phase 2Results posted
• SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol SupplementationTerminatedNCT01434745Not applicableResults posted
• Pharmacokinetics (PK)/Safety Study of Atorvastatin in Children With Kawasaki Disease and Coronary Artery AbnormalitiesCompletedNCT01431105Phase 1/2Results posted
• Drug-Drug Interaction of Cardizem LA (Diltiazem Hydrochloride) on PitavastatinCompletedNCT01422382Phase 4Results posted
• Drug-Drug Interaction of Darunavir/Ritonavir on PitavastatinCompletedNCT01422369Phase 4Results posted
• Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed DyslipidemiaCompletedNCT01420549Phase 3Results posted
• A Study of LY2484595 in Japanese SubjectsCompletedNCT01375075Phase 2Results posted
• A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants With High Cholesterol (MK-0653C-190 AM1)CompletedNCT01370603Phase 3Results posted
• A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1)CompletedNCT01370590Phase 3Results posted
• A Formulation Screening Study of Dalcetrapib and Atorvastatin in Healthy VolunteersCompletedNCT01363999Phase 1Results posted
• Atorvastatin on Biomarkers of Inflammation, Coagulopathy, Angiogenesis & T-cellsCompletedNCT01351025Phase 2Results posted
• Cyclosporine, Pravastatin Sodium, Etoposide, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid LeukemiaTerminatedNCT01342887Phase 1/2Results posted
• A Multiple Dose Study of PF-04950615 (RN316) in Subjects on High Doses of StatinsCompletedNCT01342211Phase 2Results posted
• The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT)TerminatedNCT01341730Phase 4Results posted
• Efficacy and Safety of Extended-Release Niacin/ Laropiprant/Simvastatin Tablets in Participants With Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-143)TerminatedNCT01335997Phase 3Results posted
• Drug-drug Interaction of Empagliflozin (BI 10773) and SimvastatinCompletedNCT01304329Phase 1Results posted
• A 12-Week Study Comparing Pitavastatin 4 mg vs. Pravastatin 40 mg in HIV-Infected SubjectsCompletedNCT01301066Phase 4Results posted
• Rosuvastatin to Lower Circulating Tissue Factor Bearing Microparticles in Metastatic Breast CancerCompletedNCT01299038Phase 2Results posted
• A Study to Evaluate Efficacy and Safety of Extended-Release Niacin + Laropiprant + Simvastatin in Participants With Primary Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-118)TerminatedNCT01294683Phase 3Results posted
• Modulation of Monocyte Activation by Atorvastatin in HIV InfectionCompletedNCT01263938Phase 4Results posted
• Fish Oil Versus Statins Versus Placebos in Reducing Atrial Fibrillation in Patients Undergoing Thoracic Surgery for Lung CancerTerminatedNCT01259284Phase 2/3Results posted
• Prevail-Us: A Study Of Pitavastatin 4 mg Vs. Pravastatin 40 mg In Patients With Primary Hyperlipidemia Or Mixed DyslipidemiaCompletedNCT01256476Phase 4Results posted
• LY2189265 and Atorvastatin Interaction StudyCompletedNCT01250834Phase 1Results posted
• Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte InteractionsCompletedNCT01241903Phase 1Results posted

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