Hydroxymethylglutaryl-CoA Reductase Inhibitors: all 1,715 studies that test it

Page 17 of 18. Open to participants first (139), then studies with results posted, then the rest; newest registration first within each.

• Simvastatin Treatment of Patients With Acute Optic NeuritisStatus unknownNCT00261326Phase 3
• High-dose Periop Statins for Prevention of DVTCompletedNCT00259662Not applicable
• PROMISS: Simvastatin Prevents the Contrast Induced Acute Renal Failure in Patients With Renal Insufficiency Undergoing Coronary AngiographyCompletedNCT00259441Phase 4
• Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.CompletedNCT00256178Phase 3
• A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and HypercholesterolemiaCompletedNCT00254475Phase 3
• Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With HypercholesterolemiaCompletedNCT00249912Phase 3
• Evaluation of Efficacy and Safety of Combined Omacor (Omega-3-acid Ethyl Esters) and Simvastatin Therapy in Hypertriglyceridemic SubjectsCompletedNCT00246701Phase 3
• Neuroprotection With Statin Therapy for Acute Recovery Trial (Neu-START)CompletedNCT00243880Phase 1
• Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS)CompletedNCT00242944Phase 4
• A Safety Study of Combination Treatment With Avonex and Zocor in Relapsing Remitting Multiple SclerosisStatus unknownNCT00242268Phase 3
• DISCOVERY Asia - Crestor in Type IIa and IIb HypercholesteremiaCompletedNCT00241488Phase 3
• A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID)CompletedNCT00240318Phase 3
• A Study to Investigate the Effect of Rosuvastatin (CRESTOR®) on High Density Lipoprotein Kinetics in Patients With the Metabolic SyndromeCompletedNCT00240305Phase 3
• Rosuvastatin Impact on Ventricular Remodelling Lipids and CytokinesCompletedNCT00240292Phase 3
• The Effect of Rosuvastatin on Aortic Stiffness in Hemodialysis Patients in the AURORA StudyCompletedNCT00240279Phase 3
• Study of High Density Lipoprotein Cholesterol (HDL-C)-Raising Mechanism of Rosuvastatin (CRESTOR™) by Quantifying the Key Steps of Reverse Cholesterol Transport (RCT)CompletedNCT00240266Phase 3
• Direct Statin Comparison of LDL-C Values: an Evaluation of Rosuvastatin TherapyCompletedNCT00239330Phase 3
• A Randomized, Double-Blind, Placebo-Controlled Trial of Simvastatin on Subarachnoid Hemorrhage-Induced VasospasmCompletedNCT00235963Phase 1/2
• Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart DiseaseCompletedNCT00235950Phase 4
• Dutch Sub Study: Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA). PET Sub StudyCompletedNCT00228514Phase 3
• Pravastatin for Hyperlipidaemia in HIV.CompletedNCT00227500Phase 4
• A Study Measuring Effects on Intima Media Thickness: An Evaluation of Rosuvastatin 40 mg (METEOR)CompletedNCT00225589Phase 3
• Pravastatin and Protease Inhibitors in HIV-infected PatientsCompletedNCT00221754Phase 2
• LUNAR IIIb Study Comparing Rosuvastatin and Atorvastatin in Subjects With Acute Coronary SyndromesCompletedNCT00214630Phase 3
• Type III DysbetalipoproteinemiaCompletedNCT00214604Phase 3
• Crestor Versus Placebo in Subjects With Heart FailureCompletedNCT00206310Phase 3
• Statin and PAF in Patients With PacemakerStatus unknownNCT00201552Not applicable
• Safety and Efficacy of Pravastatin in Relapsing-remitting Multiple SclerosisCompletedNCT00200655Phase 3
• Statins in Proteinuric NephropathiesCompletedNCT00199927Phase 3
• Differences in Atorvastatin Metabolite Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced MyotoxicityCompletedNCT00199745Phase 4
• A 16 Week Comparative Study of Fenofibrate Versus Ezetimibe as Add-on Therapy to AtorvastatinCompletedNCT00195793Phase 3
• SLIM: Combined Effects of Slo-Niacin and Atorvastatin on Lipoproteins and Inflammatory Markers in HyperlipidemiaCompletedNCT00194402Phase 4
• Effects of Ezetimibe on Postprandial Hyperlipidemia and Endothelial FunctionCompletedNCT00189085Phase 4
• Pharmacokinetic Study of Rosuvastatin and Lopinavir/Ritonavir in HIV PatientsCompletedNCT00184951Phase 2
• The Effect of Statin Use on Vascular Function in Hypertensive SubjectsTerminatedNCT00181181Phase 4
• Improving Symptoms of Schizophrenia and Schizoaffective Disorder by Supplementing Medications With PravastatinCompletedNCT00177580Phase 4
• Statin Therapy in Asymptomatic Aortic StenosisStatus unknownNCT00176410Phase 2
• Impact of Rosuvastatin on Endothelial Function and Inflammation in Patients With Chronic Heart FailureCompletedNCT00176332Phase 2
• Comparing Amlodipine/Atorvastatin Co-Administration To Amlodipine Alone In Patients With Hypertension And DyslipidemiaCompletedNCT00174330Phase 4
• The Effects of Atorvastatin on Vulnerable Plaques in Untreated Dyslipidemic Patients.CompletedNCT00172419Not applicable
• Efficacy and Safety of Fluvastatin or Valsartan and Their Combination in Dyslipidemic Patients With Hypertension and Endothelial DysfunctionCompletedNCT00171327Phase 4
• Efficacy and Safety Study of Fluvastatin and Ezetimibe Combined Versus Fluvastatin AloneCompletedNCT00171288Phase 3
• Fluvastatin in the Therapy of Acute Coronary SyndromeCompletedNCT00171275Phase 4
• Trial to Evaluate the Efficacy of Fluvastatin on Certain MarkersCompletedNCT00171262Phase 4
• Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial HypercholesterolemiaCompletedNCT00171236Phase 3
• A 10-12 Week Study to Evaluate the Safety and Efficacy of 320 mg Valsartan and 80 mg Simvastatin in Combination and as Monotherapies in Treating Hypertension and HypercholesterolemiaCompletedNCT00171093Phase 3
• EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)CompletedNCT00166530Phase 4
• Atorvastatin in MyelomaStatus unknownNCT00164086Phase 1
• Comparative Atorvastatin Pleiotropic EffectsCompletedNCT00163202Phase 4
• Vasomotor Reactivity In Cerebral Small Vessel Disease And New Approach To Treat Lacunar StrokeCompletedNCT00163150Phase 4
• Rosuvastatin and Renal Endothelial FunctionCompletedNCT00160745Phase 2
• Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHDCompletedNCT00159835Phase 4
• Double Blind Atorvastatin Amlodipine StudyCompletedNCT00159718Phase 4
• Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)CompletedNCT00157924Phase 4
• Ezetimibe and Simvastatin in Dyslipidemia of DiabetesCompletedNCT00157482Phase 2
• Comparison of Vascular Effects After Therapy With Irbesartan and Atorvastatin.CompletedNCT00154024Not applicable
• To Evaluate the Safety and Effectiveness of Atorvastatin Plus a Cholinesterase Inhibitor in AD Patients.CompletedNCT00151502Phase 3
• Clinical Utility of Caduet in Achieving Blood Pressure and Lipid Endpoints in a Specific Patient PopulationCompletedNCT00150384Phase 4
• Canadians Achieve Cholesterol Targets Fast With Atorvastatin Stratified TitrationCompletedNCT00150371Phase 3
• Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous StrokeCompletedNCT00147602Phase 4
• EARLY IFNB-1a and Simvastatin Combination Therapy in Clinically Isolated Syndrome Suggestive of Multiple SclerosisCompletedNCT00146068Phase 4
• Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Subjects With A Genetic Cholesterol Disorder.TerminatedNCT00145431Phase 3
• Use of Atorvastatin (Lipitor) to Decrease Panel Reactive Antibody TitersCompletedNCT00143741Phase 1
• Efficacy of Lapaquistat Acetate and Atorvastatin on Blood Cholesterol Levels in Subjects With Primary HypercholesterolemiaCompletedNCT00143676Phase 3
• Evaluating Atorvastatin With Omega-3 Fatty Acids in Cardiovascular Risk Reduction in Patients With Type 2 DiabetesCompletedNCT00141232Phase 4
• Efficacy And Safety Study Of Atorvastatin Versus Simvastatin In Type 2 Diabetic Subjects With HypercholesterolemiaCompletedNCT00141141Phase 4
• Assess HDL-C Increase And Non-HDL Lowering Effect Of Torcetrapib/Atorvastatin Vs. FenofibrateCompletedNCT00139061Phase 3
• A Study of Torcetrapib/Atorvastatin vs Atorvastatin Alone or Placebo in Patients With High CholesterolCompletedNCT00138762Phase 3
• Other Effects of Fluvastatin Are Investigated in Patients With Metabolic SyndromeCompletedNCT00138528Phase 4
• Lipitor Trial To Study The Effect Of Torcetrpib/Atorvastatin To Atorvastatin Alone.CompletedNCT00137462Phase 3
• Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.CompletedNCT00136981Phase 3
• A Swiss Study With Atorvastatin in Hyperlipidemic Patients Measuring LDL-CholesterolCompletedNCT00136942Phase 3
• Efficacy and Safety of Fluvastatin in Different Doses in Adults With Mixed Dyslipidemia or Primary HypercholesterolemiaCompletedNCT00136799Phase 3
• Improving Diabetic Foot Ulcers With AtorvastatinCompletedNCT00134550Phase 2
• Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol DisorderCompletedNCT00134511Phase 3
• A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High TriglyceridesCompletedNCT00134498Phase 3
• Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial HypercholerolemiaCompletedNCT00134485Phase 3
• A Study Examining Torcetrapib/Atorvastatin And Atorvastatin Effects On Clinical CV Events In Patients With Heart DiseaseTerminatedNCT00134264Phase 3
• Carotid B-mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrapib/Atorvastatin to Atorvastatin.TerminatedNCT00134238Phase 3
• A Coronary IVUS Study to Compare Torcetrapib/Atorvastatin to Atorvastatin Alone in Subjects With Coronary Heart DiseaseCompletedNCT00134173Phase 3
• A Study in People With High CholesterolCompletedNCT00133380Phase 2
• A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)CompletedNCT00132717Phase 3
• Pediatric Atorvastatin in Diabetes Intervention Trial (PADIT)CompletedNCT00130481Not applicable
• Trial to Evaluate the Effect of Statins on Asthma Control of Patients With Chronic AsthmaCompletedNCT00126048Phase 2/3
• Fluvastatin in Adults With Dislipidemia With History of Muscle ProblemsCompletedNCT00125125Phase 4
• Transesophageal Magnetic Resonance Imaging (MRI) in Conjunction With Lipid Lowering MeasuresCompletedNCT00125060Not applicable
• Atorvastatin and Endothelial Function in Type 2 Diabetes Mellitus (ATTEND-Study)CompletedNCT00124397Phase 4
• Lupus Atherosclerosis Prevention StudyCompletedNCT00120887Phase 4
• Atorvastatin (Lipitor) to Prevent Bone PainCompletedNCT00120133Not applicable
• Association Between Systemic Exposure of Atorvastatin and Metabolites and Atorvastatin-induced MyotoxicityCompletedNCT00120055Phase 4
• Rosuvastatin Versus Pravastatin in HIV Patients Treated With Boosted Protease Inhibitors (PI) (ANRS126)CompletedNCT00117494Phase 4
• MARS - Monitored Atherosclerosis Regression StudyCompletedNCT00116870Phase 2/3
• Rho Kinase in Patients With AtherosclerosisCompletedNCT00115830Phase 3
• The Effects of Atorvastatin in Patients With AtherosclerosisCompletedNCT00115817Phase 3
• A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077)CompletedNCT00110435Phase 3
• Pravastatin, Idarubicin, and Cytarabine in Treating Patients With Acute Myeloid LeukemiaCompletedNCT00107523Phase 1
• A Study to Evaluate an Investigational Drug in Patients With Mixed Hyperlipidemia (0653A-071)(COMPLETED)CompletedNCT00093899Phase 3
• MK0653A (Ezetimibe (+) Simvastatin) Compared to an Approved Drug (Atorvastatin) for the Treatment of High Cholesterol (0653A-051)(COMPLETED)CompletedNCT00092690Phase 3
• Effectiveness of Two Approved Drugs in Lowering High Cholesterol (0733-224)CompletedNCT00092157Phase 3
• Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Drugs in Patients With Elevated Cholesterol Levels (0653A-058)CompletedNCT00090298Phase 3

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