Hydroxymethylglutaryl-CoA Reductase Inhibitors: all 1,715 studies that test it

Page 5 of 18. Open to participants first (139), then studies with results posted, then the rest; newest registration first within each.

• Study of Effectiveness of Lovastatin to Prevent Radiation-Induced Rectal InjuryCompletedNCT00580970Phase 2Results posted
• The Use of Statins Following a Left Atrial Catheter Ablation Procedure to Prevent Atrial FibrillationCompletedNCT00579098Phase 4Results posted
• Evaluation of Atorvastatin on Atherosclerosis CompositionCompletedNCT00576576Not applicableResults posted
• Simvastatin in Waldenstrom's MacroglobulinemiaTerminatedNCT00575965Phase 2Results posted
• Statin Therapy Versus Placebo Prior to ProstatectomyCompletedNCT00572468Not applicableResults posted
• Single Dose Pravastatin Pharmacokinetics in Pediatric Peritoneal Dialysis PatientsTerminatedNCT00571194Phase 1Results posted
• Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRSCompletedNCT00559962Phase 2Results posted
• The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's DiseaseTerminatedNCT00548145Not applicableResults posted
• Evaluating How the Treatments in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study Affect Diabetic Retinopathy (The ACCORD Eye Study)CompletedNCT00542178Phase 3Results posted
• Lipitor Korean Atorvastatin Goal Achievement Across Risk Levels StudyCompletedNCT00540293Phase 4Results posted
• Nephropathy In Type 2 Diabetes and Cardio-renal EventsCompletedNCT00535925Phase 4Results posted
• A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)CompletedNCT00535405Phase 3Results posted
• Pilot Mouthwash Study of Pioglitazone and Simvastatin in Healthy VolunteersCompletedNCT00531882Not applicableResults posted
• A Trial of Lipitor (Atorvastatin) for the Treatment of Polycystic Ovary Syndrome (PCOS) in Women With Elevated Low-density Lipoprotein (LDL) CholesterolCompletedNCT00529542Phase 2Results posted
• Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM)CompletedNCT00529191Phase 2Results posted
• Statins for the Early Treatment of SepsisTerminatedNCT00528580Phase 2Results posted
• 12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With EzetimibeCompletedNCT00525824Phase 3Results posted
• Effect of Policosanol as Monotherapy and Adjunctive to Statin TherapyCompletedNCT00510809Not applicableResults posted
• Simvastatin (Zocor) Therapy in Sickle Cell DiseaseCompletedNCT00508027Phase 1/2Results posted
• A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)CompletedNCT00496730Phase 3Results posted
• Clinical Utility of Endothelial Dysfunction in PADTerminatedNCT00491751Phase 1Results posted
• Effect of a Fibrate and a Statin on Endothelial DysfunctionTerminatedNCT00491400Not applicableResults posted
• Zoledronate With Atorvastatin in Renal Cell CarcinomaCompletedNCT00490698Phase 2Results posted
• Acetaminophen or Fluvastatin Compared to Placebo on the Transient Post-Dose Symptoms (PDS) Following an Intravenous (i.v.) Infusion of a Single Dose of Zoledronic Acid 5mg, in Post-menopausal Women With Low Bone MassCompletedNCT00489424Phase 4Results posted
• Use of Simvastatin for the Prevention of Vasospasm in Aneurysmal Subarachnoid HemorrhageTerminatedNCT00487461Not applicableResults posted
• Evaluating Simvastatin's Potential Role in TherapyCompletedNCT00486044Phase 2Results posted
• Effects of Statin and Ezetimibe Association on Kinetics of Artificial ChilomicronsCompletedNCT00481351Phase 4Results posted
• MK-0524B Lipid Study (MK-0524B-063)CompletedNCT00479882Phase 3Results posted
• A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED)CompletedNCT00479713Phase 3Results posted
• Study of Extended Release Niacin/Laropiprant on Lipids (0524A-067)CompletedNCT00479388Phase 3Results posted
• Clinical Trial of Zocor (Simvastatin) and Vytorin (Ezetimibe/Simvastatin) in Adolescents With Type 1 DiabetesCompletedNCT00477204Phase 2Results posted
• Antiplatelet and Anti-inflammatory Effects of Statins and EzetimibeCompletedNCT00474123Not applicableResults posted
• Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic PatientsCompletedNCT00473655Phase 4Results posted
• Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak SyndromeTerminatedNCT00467831Phase 1/2Results posted
• An Open-Label Study to Compare the Lipid Effects of Niacin ER and Simvastatin (NS) to Atorvastatin in Subjects With Hyperlipidemia or Mixed Dyslipidemia (SUPREME)CompletedNCT00465088Phase 3Results posted
• A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With DyslipidemiaCompletedNCT00463606Phase 3Results posted
• A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)CompletedNCT00462748Phase 3Results posted
• Lovastatin in Treating Patients At High Risk of MelanomaCompletedNCT00462280Phase 2Results posted
• Effect of Statin Therapy on Disease Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD)CompletedNCT00456365Phase 3Results posted
• Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)CompletedNCT00442897Phase 4Results posted
• Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mgTerminatedNCT00427960Phase 4Results posted
• Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)CompletedNCT00418834Phase 3Results posted
• Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)CompletedNCT00413972Phase 3Results posted
• Atorvastatin to Prevent Avascular Necrosis of Bone in Steroid Treated Exacerbated Systemic Lupus ErythematosusTerminatedNCT00412841Phase 2Results posted
• Ezetimibe/Simvastatin in Patients With Metabolic Syndrome (0653A-107)(COMPLETED)CompletedNCT00409773Phase 3Results posted
• ROMEO (Rosuvastatin in Metabolic syndrOme)CompletedNCT00395486Phase 4Results posted
• A Study of Aspirin and Simvastatin in Pulmonary Arterial HypertensionTerminatedNCT00384865Phase 2Results posted
• Study of Atorvastatin Versus Placebo to Reduce Cardiopulmonary Complications After Thoracic SurgeryCompletedNCT00375518Not applicableResults posted
• Randomized Placebo-Controlled Trial of Atorvastatin in HIV-Positive Patients Not on Antiretroviral TherapyCompletedNCT00367458Phase 2Results posted
• Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early AtherosclerosisCompletedNCT00361283Phase 4Results posted
• PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatinCompletedNCT00355615Phase 3Results posted
• Simvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast CancerCompletedNCT00354640Phase 2Results posted
• Follow-On Study of Pitavastatin Versus Atorvastatin in Patients With Type II Diabetes Mellitus and Combined DyslipidemiaCompletedNCT00344370Phase 3Results posted
• Follow-on Protocol of Pitavastatin Versus Simvastatin in Patients With Hypercholesterolemia or Dyslipidemia and Coronary Heart Disease Risk FactorsCompletedNCT00344175Phase 3Results posted
• Effects of Atorvastatin on MyonecrosisTerminatedNCT00344019Phase 4Results posted
• Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal NeoplasiaCompletedNCT00335504Phase 2Results posted
• Simvastatin in Preventing a New Breast Cancer in Women at High Risk for a New Breast CancerCompletedNCT00334542Phase 2Results posted
• Study of Pitavastatin in Elderly Patients With Primary Hypercholesterolemia or Combined DyslipidemiaCompletedNCT00330876Phase 3Results posted
• Rosuvastatin in the Long-term Treatment of Hypercholesterolaemic Subjects With Coronary Heart DiseaseCompletedNCT00329160Phase 4Results posted
• Long-Term Extension Study of Pitavastatin in Patients With Primary Hypercholesterolemia or Combined DyslipidemiaCompletedNCT00325780Phase 3Results posted
• Study to Compare the Efficacy and Safety of Pitavastatin and SimvastatinCompletedNCT00309777Phase 3Results posted
• Study Comparing Pitavastatin and Atorvastatin in Patients With Type II Diabetes Mellitus and Combined DyslipidemiaCompletedNCT00309751Phase 3Results posted
• Study to Compare the Efficacy and Safety of Pitavastatin and SimvastatinCompletedNCT00309738Phase 3Results posted
• Lovastatin for the Treatment of Mildly Active Rheumatoid ArthritisTerminatedNCT00302952Phase 2Results posted
• Study to Evaluate the Long-Term Safety and Efficacy of ABT-335, in Combination With Three Different Statins in Subjects With Mixed Dyslipidemia.CompletedNCT00300430Phase 3Results posted
• Prospective Evaluation of Proteinuria and Renal Function in Non-diabetic Patients With Progressive Renal DiseaseCompletedNCT00296400Phase 2Results posted
• Prospective Evaluation of Proteinuria and Renal Function in Diabetic Patients With Progressive Renal DiseaseCompletedNCT00296374Phase 2Results posted
• Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024)CompletedNCT00289900Phase 3Results posted
• Phase 2 Study of Lovastatin as Breast Cancer ChemopreventionTerminatedNCT00285857Phase 2Results posted
• Atorvastatin to Treat Pulmonary SarcoidosisCompletedNCT00279708Phase 2Results posted
• To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)CompletedNCT00271817Phase 3Results posted
• Study to Compare the Efficacy and Safety of Pitavastatin and Pravastatin in Elderly PatientsCompletedNCT00257686Phase 3Results posted
• Atorvastatin Therapy for the Prevention of Atrial Fibrillation (SToP-AF)TerminatedNCT00252967Phase 3Results posted
• Study to Compare the Efficacy of Pitavastatin With That of Atorvastatin in Lowering Cholesterol LevelsCompletedNCT00249249Phase 3Results posted
• AURORA: Crestor 10mg Versus Placebo in Subjects With End-stage Renal Disease (ESRD)CompletedNCT00240331Phase 3Results posted
• JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) EventsTerminatedNCT00239681Phase 3Results posted
• Statin Therapy in Heart Failure: Potential Mechanisms of BenefitCompletedNCT00233480Phase 4Results posted
• Japan Statin Treatment Against Recurrent Stroke (J-STARS)CompletedNCT00221104Phase 3Results posted
• Phase 2 Study of Atorvastatin Safety and Antitumor Effects in Non-Hodgkin's LymphomaCompletedNCT00185731Phase 2Results posted
• Simvastatin as a Treatment for Pulmonary HypertensionCompletedNCT00180713Phase 1/2Results posted
• Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)CompletedNCT00166504Phase 4Results posted
• Effect of Statins on Oxidative Stress and Endothelial Progenitor CellsCompletedNCT00166036Phase 2Results posted
• ARREST PAD (Peripheral Arterial Disease)CompletedNCT00153166Phase 2/3Results posted
• Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)CompletedNCT00129402Phase 3Results posted
• Study of Heart and Renal ProtectionCompletedNCT00125593Phase 4Results posted
• Study of the Effectiveness of Additional Reductions in Cholesterol and HomocysteineCompletedNCT00124072Phase 3Results posted
• Detection of Plaque Inflammation by Positron Emission Tomography (PET)-Effects of Simvastatin on Plaque InflammationCompletedNCT00114504Not applicableResults posted
• Atorvastatin (Lipitor) Therapy in Patients With Clinically Isolated Syndrome (CIS) at Risk for Multiple SclerosisCompletedNCT00094172Phase 2Results posted
• An Investigational Drug on Clinical Outcomes in Patients With Aortic Stenosis (Narrowing of the Major Blood Vessel of the Heart)(MK-0653A-043 AM4)(COMPLETED)CompletedNCT00092677Phase 3Results posted
• Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)CompletedNCT00065806Phase 3Results posted
• The Role of Bisphosphonate and Simvastatin Combination on Therapeutic Response in Breast Cancer With Bone Metastasis Via Dicckopf-1 PathwayCompletedNCT07823751Not applicable
• Therapeutic Prospects of HMG-CoA Reductase Inhibitors, Atorvastatin and Rosuvastatin, in Osteoporotic PatientsCompletedNCT07717788Not applicable
• Alveolar Ridge Splitting With Simvastatin/PRF Composite and Simultaneous Implant PlacementCompletedNCT07692620Not applicable
• The Potential Cardioprotective Effect of Addition of Atorvastatin in Breast Cancer PatientsCompletedNCT07668076Phase 2
• A Study to Assess the Effect of HRS-1301 on the Pharmacokinetics of Midazolam and Atorvastatin in Healthy ParticipantsCompletedNCT07608705Phase 1
• A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.CompletedNCT07567781Phase 1
• Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High CholesterolCompletedNCT07564726Phase 3
• Adjunctive Role of Statin Therapy on Airway Inflammation and Clinical Consequences of Chronic Obstructive Pulmonary DiseaseCompletedNCT07549932Not applicable
• A Study to Investigate the Effect of Elecoglipron on Rosuvastatin and Atorvastatin in Healthy ParticipantsActive, not recruitingNCT07534592Phase 1
• A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)CompletedNCT07530289Phase 1

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