Hydroxymethylglutaryl-CoA Reductase Inhibitors: all 1,715 studies that test it

Page 4 of 18. Open to participants first (139), then studies with results posted, then the rest; newest registration first within each.

• Statins in Children With Type 1 Diabetes and HypercholesterolemiaCompletedNCT01236365Phase 3Results posted
• Atorvastatin Calcium and Celecoxib in Treating Patients With Rising PSA Levels After Local Therapy for Prostate CancerCompletedNCT01220973Phase 2Results posted
• Use of Rosuvastatin in HIV-Infected Subjects to Modulate Cardiovascular RisksCompletedNCT01218802Phase 2Results posted
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Administering Multiple Oral Doses of GSK1292263 Alone and With AtorvastatinCompletedNCT01218204Phase 2Results posted
• Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque RegressionCompletedNCT01212900Phase 4Results posted
• Open Label Study To Evaluate The Long-Term Safety Profiles Of Caduet In Japanese PatientsCompletedNCT01190007Phase 4Results posted
• Atorvastatin for the Prophylaxis of Acute GVHD in Patients Undergoing Matched Sibling Allogeneic TransplantationCompletedNCT01175148Phase 2Results posted
• MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162)CompletedNCT01154036Phase 3Results posted
• Effects of Simvastatin on BiomarkersCompletedNCT01142336Phase 4Results posted
• A Study of LY2484595 in Patients With High LDL-C or Low HDL-CCompletedNCT01105975Phase 2Results posted
• Targeting Sympathetic Overactivity in Heart Failure Patients With StatinsCompletedNCT01097785Not applicableResults posted
• Effects of Atorvastatin on Endothelial Progenitor Cells After Coronary SurgeryCompletedNCT01096875Phase 4Results posted
• Effects of Pravastatin on Cholesterol, Inflammation and Cognition in SchizophreniaCompletedNCT01082588Phase 4Results posted
• An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial HypercholesterolaemiaCompletedNCT01078675Phase 3Results posted
• Efficacy of Statins In Prevention of CINTerminatedNCT01071993Not applicableResults posted
• Rosuvastatin in Visceral AdiposityCompletedNCT01068626Phase 3Results posted
• Simvastatin Therapy for Moderate and Severe COPDTerminatedNCT01061671Phase 3Results posted
• Study Of The Effects Of Atorvastatin On Cholesterol Levels In Rheumatoid Arthritis Patients Taking CP-690,550CompletedNCT01059864Phase 2Results posted
• Drug-Drug Interaction of Lopinavir/Ritonavir on PitavastatinCompletedNCT01057433Phase 4Results posted
• Safety, Tolerability, and Pharmacokinetic of Single Dose of Pitavastatin 4 mg in Severe Renal Patients Versus Healthy Adult VolunteersCompletedNCT01043094Phase 4Results posted
• Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical ProtocolTerminatedNCT01013870Phase 2Results posted
• Rosuvastatin in Treating Patients With Stage I or Stage II Colon Cancer That Was Removed By SurgeryTerminatedNCT01011478Phase 3Results posted
• Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome.CompletedNCT00988364Phase 4Results posted
• Effect of Repeated Administration of Eslicarbazepine Acetate on the Pharmacokinetics of Simvastatin in Healthy SubjectsCompletedNCT00987558Phase 1Results posted
• Effect of Rosuvastatin on Endothelial FunctionTerminatedNCT00986999Phase 2/3Results posted
• Cardiovascular Prevention for Persons With HIVCompletedNCT00982189Not applicableResults posted
• Effects of Short Term, High Dose Atorvastatin Therapy on Periprocedural Myonecrosis and Platelet Inhibition After Percutaneous Coronary Intervention (PCI)TerminatedNCT00979940Not applicableResults posted
• Statins for Acutely Injured Lungs From SepsisTerminatedNCT00979121Phase 3Results posted
• Pilot Trial of Statin Use in Burn PatientsCompletedNCT00978419Phase 2Results posted
• STIP: Statin Trial for Influenza PatientsTerminatedNCT00970606Not applicableResults posted
• Statin Therapy to Improve Atherosclerosis in HIV PatientsCompletedNCT00965185Not applicableResults posted
• Drug-Drug Interaction Study Between Colchicine and AtorvastatinCompletedNCT00960323Phase 1Results posted
• MK0524B Bioequivalence Study (0524B-070)CompletedNCT00943124Phase 1Results posted
• Statin Effects on Beta-Amyloid and Cerebral Perfusion in Adults at Risk for Alzheimer's DiseaseCompletedNCT00939822Phase 2Results posted
• Lipid Biomarker Study in Men With Dyslipidemia After Simvastatin Treatment (Study MK-0000-140)(COMPLETED)CompletedNCT00935259Phase 1Results posted
• Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)CompletedNCT00932620Phase 4Results posted
• Effect of Rosuvastatin Therapy in Patients With Stable Chronic Obstructive Pulmonary DiseaseCompletedNCT00929734Phase 2Results posted
• Bioequivalence Study Comparing A New 10 Mg Atorvastatin Tablet To A 10 Mg Atorvastatin Commercial TabletCompletedNCT00917579Phase 4Results posted
• Lovastatin in Reducing Side Effects After Radiation Therapy in Women With Breast CancerTerminatedNCT00902668Phase 2Results posted
• Efficacy and Safety Study of Pitavastatin Compared to atoRvastatin in Type 2 dIabeTes Mellitus With HypercholesterolemiaCompletedNCT00889226Phase 4Results posted
• A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With ProgeriaCompletedNCT00879034Phase 2Results posted
• Evaluation of Ezetimibe and Atorvastatin Coadministration Versus Atorvastatin or Rosuvastatin Monotherapy in Japanese Patients With Hypercholesterolemia (Study P06027)(COMPLETED)CompletedNCT00871351Phase 4Results posted
• Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)CompletedNCT00862251Phase 3Results posted
• A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1CompletedNCT00853580Phase 2Results posted
• Quality of Life in Patients With Statin-Associated MyopathyTerminatedNCT00850460Phase 4Results posted
• Bioavailability Study for New Atorvastatin FormulationCompletedNCT00844376Phase 4Results posted
• S0919 Idarubicin, Cytarabine, and Pravastatin in Treating Patients With Relapsed Acute Myeloid LeukemiaCompletedNCT00840177Phase 2Results posted
• Pravastatin Sodium 80 mg Tablets Under Fasting ConditionsCompletedNCT00830258Phase 1Results posted
• Pravastatin 80 mg Tablets Dosed in Healthy Subjects Under Non-Fasting ConditionsCompletedNCT00829309Phase 1Results posted
• Atorvastatin Three Year Pediatric StudyCompletedNCT00827606Phase 3Results posted
• Simvastatin With or Without Ezetimibe and Atherothrombotic Biomarker AssessmentCompletedNCT00819403Phase 4Results posted
• The PostprAndial eNdothelial Function After Combination of Ezetimibe and simvAstatin StudyCompletedNCT00817843Phase 4Results posted
• Effect of Crestor (Rosuvastatin) on Lipid Levels in Patients With Metabolic SyndromeCompletedNCT00815659Phase 4Results posted
• Merck Carotid Atherosclerosis Trial (MK-0000-111)(COMPLETED)CompletedNCT00804843Phase 2Results posted
• Statins and Cerebral Blood Flow in Subarachnoid Hemorrhage (SAH)CompletedNCT00795288Phase 1/2Results posted
• Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for SchizophreniaTerminatedNCT00794963Not applicableResults posted
• Short-term Atorvastatin's Effect on Acute Kidney Injury Following Cardiac SurgeryCompletedNCT00791648Not applicableResults posted
• A Study of Ezetimibe Added On to Rosuvastatin Versus Up Titration of Rosuvastatin in Patients With Hypercholesterolemia (MK0653-139)CompletedNCT00783263Phase 3Results posted
• Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)CompletedNCT00782184Phase 3Results posted
• Effects of Statins on Lower Extremity Arterial Function Assessed by Magnetic Resonance ImagingTerminatedNCT00770679Not applicableResults posted
• Statins and Endothelial Function in Patients With Coarctation of the AortaTerminatedNCT00767572Phase 4Results posted
• Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) CholesterolCompletedNCT00762164Phase 4Results posted
• Does Atorvastatin Prevent Post Operative Atrial Fibrillation After Pulmonary Resection: A Randomized Clinical StudyCompletedNCT00756886Not applicableResults posted
• A Diabetes Study to Treat A Population Previously Not at TargetCompletedNCT00747149Phase 4Results posted
• Feasibility Study of Simvastatin in Hodgkin's Lymphoma SurvivorsTerminatedNCT00746603Not applicableResults posted
• Women With Chest Pain and Normal Coronary Arteries StudyTerminatedNCT00743197Not applicableResults posted
• 8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial HypercholesterolemiaCompletedNCT00739999Phase 1Results posted
• Effect of Simvastatin on Endothelial Function in Premenopausal Women With Systemic Lupus Erythematosus (0733-271)(TERMINATED)TerminatedNCT00739050Phase 4Results posted
• Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients (MK0653A-168)TerminatedNCT00738972Phase 3Results posted
• Atorvastatin Pre-Treatment Study In Asian Patients With Acute Coronary SyndromeCompletedNCT00728988Phase 4Results posted
• Simvastatin For Intracerebral Hemorrhage StudyTerminatedNCT00718328Phase 2Results posted
• Evaluate the Utility of 18FDG-PET as a Tool to Quantify Atherosclerotic Plaque (MK-0000-081 AM3)(COMPLETED)CompletedNCT00703261Phase 1Results posted
• Statin Therapy for Ischemic and Nonischemic CardiomyopathyCompletedNCT00701220Phase 4Results posted
• Evaluate Safety and Efficacy of AEGR-733 and Atorvastatin vs Atorvastatin Monotherapy in HypercholesterolemiaCompletedNCT00690443Phase 2Results posted
• A Study of MK-6213 Co-Administered With Atorvastatin in Participants With Hypercholesterolemia (MK-6213-006)CompletedNCT00687271Phase 2Results posted
• Fasting Bioavailability Study of Lovastatin Tablets and Mevacor TabletsCompletedNCT00685685Phase 1Results posted
• Fed Bioavailability Study of Lovastatin Tablets and Mevacor TabletsCompletedNCT00684723Phase 1Results posted
• Compare the Efficacy of Rosuvastatin to Atorvastatin in High Risk Patients With HypercholesterolemiaCompletedNCT00683618Phase 3Results posted
• 30 Week Study of the Combination of ABT-335 and Rosuvastatin Compared to Rosuvastatin Monotherapy for Subjects With Dyslipidemia and Stage 3 Chronic Kidney DiseaseCompletedNCT00680017Phase 3Results posted
• An Open-label Extension to Assess the Continued Efficacy of Omacor Plus SimvastatinCompletedNCT00678743Phase 4Results posted
• Statin Therapy in the Treatment of SepsisCompletedNCT00676897Phase 2/3Results posted
• Effects of Fluvastatin on Proinflammatory and Prothrombotic Markers in Antiphospholipid Syndrome PatientsCompletedNCT00674297Phase 2Results posted
• Implications for Treatment of the Metabolic SyndromeCompletedNCT00666029Phase 2Results posted
• IMPAACT P1063: Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With HyperlipidemiaTerminatedNCT00663234Phase 1/2Results posted
• Begin With The Right Patients With Dual-Inhibition Action Therapy Through Vytorin for Newly Diagnosed Dyslipidemia Patients (0653A-172)(COMPLETED)CompletedNCT00654628Phase 4Results posted
• Coadministration of Ezetimibe and Atorvastatin in Patients With Primary Hypercholesterolemia (P05456)CompletedNCT00654095Phase 3Results posted
• Coadministration of Ezetimibe and Simvastatin in Patients With Primary Hypercholesterolemia (P05457)CompletedNCT00653523Phase 3Results posted
• Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)CompletedNCT00652327Phase 4Results posted
• Investigation of Simvastatin in Secondary Progressive Multiple SclerosisCompletedNCT00647348Phase 2Results posted
• Safety of Red Yeast Rice for High Cholesterol in Individuals With Statin IntoleranceCompletedNCT00639223Phase 2Results posted
• Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic PatientsCompletedNCT00631189Phase 4Results posted
• Genetic Predictors of Variability in the Drug-drug Interaction Between Darunavir/Ritonavir and PravastatinCompletedNCT00630734Phase 4Results posted
• CRESTOR Athero Imaging Head to Head IVUS StudyCompletedNCT00620542Phase 3Results posted
• The Effect of Lipitor on Aortic StenosisTerminatedNCT00590135Phase 4Results posted
• Effect of Acute Statin Treatment in Patients Undergoing Percutaneous Coronary InterventionTerminatedNCT00588471Not applicableResults posted
• Comprehensive Magnetic Resonance of Peripheral Arterial DiseaseCompletedNCT00587678Not applicableResults posted
• Effects of Statin Therapy on Vascular Properties and Outcomes in Diastolic Heart Failure PatientsTerminatedNCT00585611Not applicableResults posted
• A Phase II Study of Interaction of Lovastatin and Paclitaxel For Patients With Refractory or Relapsed Ovarian CancerTerminatedNCT00585052Phase 2Results posted
• A Study of the Proper Dosage of Lovastatin and Docetaxel for Patients With CancerTerminatedNCT00584012Phase 1Results posted
• Dose Escalation Phase I/II Study of Lovastatin With High-Dose Cytarabine for Refractory or Relapsed AMLTerminatedNCT00583102Phase 1/2Results posted

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