DrugSupplement
Choline clinical trials
- studies test it
- 32
- open now
- 6
- in phase 3
- 4
- first study started
- 1997
Keep track of what changes. Save the Choline studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
32 studies that test it; most in 2022 (4)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 2001 | 1 |
| 2006 | 1 |
| 2009 | 2 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 2 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 2 |
| 2017 | 2 |
| 2018 | 1 |
| 2019 | 1 |
| 2021 | 2 |
| 2022 | 4 |
| 2023 | 2 |
| 2024 | 2 |
| 2025 | 2 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 5
- Phase 2
- 10
- Phase 3
- 4
- Phase 4
- 3
- No phase
- 12
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 31
Virginia Polytechnic Institute and State University (3) · University of Colorado, Denver (3) · University of Minnesota (3) · The Cleveland Clinic (2) · Columbia University (2) · Cornell University (2) · Wayne State University (2) · Jeff Wozniak (1)
Often tested with
Tested in the same studies.
Carnitine (1) · Anti-Bacterial Agents (1) · Aspirin (1) · Phosphatidylcholines (1) · Folic Acid (1) · Docosahexaenoic Acids (1) · Vitamin E (1) · Betaine (1)
Studies
Open first, then newest update. How each study uses Choline is read from its arms, and is right about nine times in ten.
Testing it · 32
- Reverse Triple Negative Immune Resistant Breast CancerRecruitingPhase 2Fudan UniversityNCT05076682Written as Choline
- Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral SupportRecruitingPhase 2/3Protara TherapeuticsNCT06910943Written as Choline Chloride for Injection
- Choline and Iron DeficiencyRecruitingPhase 2/3University of MinnesotaNCT06527391Written as choline bitartrate
- Pilot Study of Prenatal Choline SupplementationRecruitingPhase 2Wayne State UniversityNCT07699393Written as Choline bitartrate
- RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol ExposureRecruitingPhase 2Wayne State UniversityNCT04395196Written as Choline bitartrate
- Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain DevelopmentRecruitingPhase 1University of Colorado, DenverNCT06379971Written as Choline
- Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in HumansCompletedNot applicableThe Cleveland ClinicNCT03039023Written as Choline Bitartrate
- Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum Disorders StudyActive, not recruitingPhase 2Jeff WozniakNCT05108974Written as Choline Bitartrate
- Choline Dose Ranging in Postmenopausal WomenCompletedNot applicableJulie DumasNCT06924541Written as Choline
- Choline Effects - Pre-symptomatic ADCompletedPhase 1Paul E SchulzNCT05880849Written as Choline
- Dietary Allowance of Methyl Donor Nutrients to Minimize Risks of Non-alcoholic Fatty Liver ProgressionCompletedNot applicableFu Jen Catholic University HospitalNCT05291104Written as Folic acid, choline chloride
- Choline Supplementation and Cardiovascular HealthCompletedNot applicableVirginia Polytechnic Institute and State UniversityNCT03646175Written as Choline
- Short Term Choline and Cardiovascular HealthCompletedNot applicableVirginia Polytechnic Institute and State UniversityNCT03327805Written as Choline
- CARNIVAL Study: Gut Flora Dependent Metabolism of Dietary CARNItine and Phosphatidylcholine and cardioVAscuLar DiseaseActive, not recruitingEarly Phase 1The Cleveland ClinicNCT01731236Written as Choline
- Choline Supplementation During Pregnancy: Impact on Attention and Social WithdrawalCompletedPhase 1University of Colorado, DenverNCT03028857Written as Choline
- Choline and Brain Functioning in Postmenopausal WomenCompletedNot applicableUniversity of VermontNCT07264257Written as Choline
- Choline and Cardiometabolic HealthCompletedNot applicableVirginia Polytechnic Institute and State UniversityNCT04764162Written as Choline
- Effect of Oral Choline Supplementation on Postoperative PainCompletedPhase 4Columbia UniversityNCT00720343Written as Choline
- Effects of a Nutraceutic Compound on Cognitive ImpairmentCompletedPhase 4Federico II UniversityNCT06200883Written as Choline Bitartrate
- Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum DisordersCompletedPhase 2University of MinnesotaNCT02735473Written as Choline bitartrate
See all 32 studies that test Choline →
Given in every arm · 1 — Choline is usual care beside what is tested
Codes
What other systems call Choline · ClinicalTrials.gg INT007214
- MeSH (NLM) D002794CholineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) N91BDP6H0XCHOLINEConfirmed FDA, NLM, Wikidata
- RxNorm 2449Confirmed FDA, Wikidata
- Wikidata Q193166cholineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61674CholineOne source FDA
- DrugBank DB00122One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D002794 | Choline | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | N91BDP6H0X | CHOLINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2449 | — | Confirmed FDA, Wikidata |
| Wikidata | Q193166 | choline | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61674 | Choline | One source FDA |
| DrugBank | DB00122 | — | One source Wikidata |
Also registered as choline bitartrate (UNII 6K2W7T9V6Y · RxNorm 2451), choline chloride (UNII 45I14D8O27 · RxNorm 1425426) and choline hydroxide (UNII 7THJ3EG9SY · RxNorm 1311084).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.