Supplement
Beta-hydroxybutyrate-1,3-butanediol monoester clinical trials
Also written Ketone ester.
- studies test it
- 27
- open now
- 5
- in phase 3
- 0
- first study started
- 2018
Keep track of what changes. Save the beta-hydroxybutyrate-1,3-butanediol monoester studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
27 studies that test it; most in 2023 (6)
| Year | Studies |
|---|---|
| 2018 | 1 |
| 2019 | 1 |
| 2020 | 4 |
| 2021 | 3 |
| 2022 | 4 |
| 2023 | 6 |
| 2024 | 5 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 2
- 7
- No phase
- 20
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 26
KU Leuven (6) · University of Aarhus (3) · Jozef Stefan Institute (2) · German Institute of Human Nutrition (2) · The Cleveland Clinic (1) · University of Bath (1) · Duke University (1) · Florida Institute for Human and Machine Cognition (1)
Studies
Open first, then newest update. How each study uses beta-hydroxybutyrate-1,3-butanediol monoester is read from its arms, and is right about nine times in ten.
Testing it · 27
- LIfestyle MEtabotype Study B (LIME-B)RecruitingNot applicableGerman Institute of Human NutritionNCT07888257Written as βHB drink (ketone ester)
- Ketone Ester for Treatment Of Acute Heart FailureNot yet recruitingNot applicableUniversity of AlbertaNCT07434466Written as Ketone Ester (KetoneAid MonoEster)
- Hemodynamic Effects of Ketone Esters in Patients With Sepsis Induced CardiomyopathyNot yet recruitingNot applicableTor Biering-SørensenNCT06952140Written as Ketone ester
- Exogenous Ketones and BehaviorRecruitingNot applicableGerman Institute of Human NutritionNCT06515717Written as ketone ester
- Treat Autosomal Dominant Polycystic Kidney Disease With Oral Ketone Ester?Not yet recruitingPhase 2Universitair Ziekenhuis BrusselNCT06100133Written as Ketone ester
- Ketones in Heart Failure With Reduced Ejection FractionCompletedPhase 2Duke UniversityNCT06195982Written as ketone ester
- Physiological Effects Ketone Ester in HeartActive, not recruitingNot applicableThe Cleveland ClinicNCT05924802Written as Ketone Ester
- Effects of Exogenous Ketone Ester Supplementation on 3-hydroxybutyrate Concentrations in Human Cerebrospinal FluidCompletedNot applicableUniversity of AarhusNCT06318299Written as Ketone Ester
- Ketone Esters for Optimization of Operator Performance in HypoxiaCompletedNot applicableFlorida Institute for Human and Machine CognitionNCT07065864Written as Ketone ester
- Ketone Esters and Metabolism During Recovery from Endurance ExerciseActive, not recruitingNot applicableUniversity of BathNCT06846840Written as Ketone ester
- Acute Effects of Exogenous Ketone Ester Administration in Heart FailureCompletedPhase 2University of PennsylvaniaNCT04633460Written as Ketone ester
- Intermittent Exogenous Ketosis (IEK) at High AltitudeActive, not recruitingNot applicableJozef Stefan InstituteNCT06097754Written as Ketone ester
- Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Cardiovascular Effects.CompletedNot applicableUniversity of AarhusNCT05236335Written as Ketone ester
- Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Metabolic Effects. (KETO-HFpEF-Metabolic)CompletedNot applicableUniversity of AarhusNCT05159570Written as Ketone ester
- Ketone Ester Supplementation and Nocturnal Blood PressureCompletedNot applicableGeorgia Southern UniversityNCT05888506Written as Ketone Ester
- Effect of Ketone Ester Supplementation on Sleep and Recovery in HypoxiaCompletedNot applicableKU LeuvenNCT06060093Written as Ketone ester
- Effect of Ketone Ester Supplementation on Hypoxic ToleranceCompletedNot applicableKU LeuvenNCT05588427Written as Ketone ester
- Role of Intermittent Exogenous Ketosis in the Physiological and Muscular Adaptive Response to Endurance TrainingActive, not recruitingPhase 2KU LeuvenNCT05932420Written as Ketone ester
- Acute Effect of Exogenous Ketosis on Sleep Architecture Following Strenuous ExerciseStatus unknownPhase 2KU LeuvenNCT05439720Written as Ketone ester
- Effect of Exogenous Ketosis During Ultra-endurance ExerciseStatus unknownPhase 2KU LeuvenNCT05407753Written as Ketone ester
See all 27 studies that test beta-hydroxybutyrate-1,3-butanediol monoester →