Drug
Aminolevulinic Acid clinical trials
Also written 5-ALA, Levulan and Gleolan.
Includes 8 studies of BF-200 ALA and 1 study of Aminolevulinic acid phosphate.
Keep track of what changes. Save the Aminolevulinic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- ALA
- 9
Studies by the year they started
107 studies that test it; most in 2014 (10); 1 more planned to start later
| Year | Studies |
|---|---|
| 1993 | 1 |
| 1997 | 1 |
| 1999 | 2 |
| 2000 | 1 |
| 2005 | 1 |
| 2006 | 1 |
| 2007 | 4 |
| 2008 | 5 |
| 2009 | 6 |
| 2010 | 3 |
| 2011 | 6 |
| 2012 | 7 |
| 2013 | 4 |
| 2014 | 10 |
| 2015 | 8 |
| 2016 | 4 |
| 2017 | 5 |
| 2018 | 1 |
| 2019 | 5 |
| 2020 | 3 |
| 2021 | 7 |
| 2022 | 2 |
| 2023 | 3 |
| 2024 | 7 |
| 2025 | 4 |
| 2026 | 6 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 28 · Other 80
DUSA Pharmaceuticals, Inc. (8) · Biofrontera Bioscience GmbH (5) · Joint Authority for Päijät-Häme Social and Health Care (4) · Roswell Park Cancer Institute (4) · University of California, Davis (3) · photonamic GmbH & Co. KG (3) · David W. Roberts (2) · NX Development Corp (2)
Often tested with
Tested in the same studies.
Oral Aminolevulinic Acid Hydrochloride (15) · Methyl aminolevulinate (5) · Photodynamic Therapy (2) · Hexaminolevulinate hydrochloride (1) · HhAntag691 (1) · Carmustine, poliferprosan 20 drug combination (1) · Iron (1) · Phototherapy (1)
Studies
Open first, then newest update. How each study uses Aminolevulinic Acid is read from its arms, and is right about nine times in ten.
Testing it · 108
- TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly GliomaRecruitingPhase 1Alpheus Medical, Inc.NCT07862647Written as 5-ALA
- A Multicenter Study to Assess the Feasibility of 5-Aminolevulinic Acid (5-ALA) in Pediatric Brain Tumor PatientsNot yet recruitingPhase 2Costas HadjipanayisNCT06907485Written as Aminolevulinic acid hydrochloride
- Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALARecruitingPhase 2Henry Ford Health SystemNCT06948552Written as 5-Aminolevulinic acid Hydrochloride (Gliolan®)
- Photodynamic Diagnosis of Kidney Cancer Using Fluorescence Endoscopy and Oral 5-ALARecruitingPhase 2Henry Ford Health SystemNCT07828704Written as 5-Aminolevulinic acid Hydrochloride (Gliolan®)
- 5-AminoLevulinic Acid Aided Resection Margins in SarcomaNot yet recruitingEarly Phase 1University of Colorado, DenverNCT07038278Written as 5-ALA
- Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)RecruitingPhase 3NX Development CorpNCT05804370Written as Gleolan
- Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain TumorRecruitingPhase 1/2Universität MünsterNCT05590689Written as Gliolan
- Fluorescence Guided Focal Cortical Dysplasia SurgeryNot yet recruitingPhase 2Hospices Civils de LyonNCT07657975Written as 5-ALA (Gliolan)
- Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral LesionsNot yet recruitingPhase 2University of Massachusetts, BostonNCT06876038Written as 5-Amino Levulinic Acid
- Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell CarcinomasRecruitingPhase 1Nathalie ZeitouniNCT06623201Written as aminolevulinic acid HCL (ALA)
- Phase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4)RecruitingPhase 3Lee's Pharmaceutical LimitedNCT06160492Written as 5-aminolevulinic acid
- The Use of 5-ALA in Paediatric Patients With High Grade Brain TumoursNot yet recruitingPhase 2University College, LondonNCT06678867Written as 5-ALA (Gliolan)
- Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)RecruitingPhase 2The Center for Clinical and Cosmetic ResearchNCT06577311Written as Aminolevulinic acid hydrochloride 10% topical gel with Red Light
- Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids TumorsRecruitingPhase 2michal rollNCT01898416Written as 5-AMINOLEVULINIC ACID (5-ALA), is a non fluorescent prodrug.
- Cryotherapy in Combination With Red Light PDT for Actinic Keratosis of Full FaceActive, not recruitingPhase 4Psoriasis Treatment Center of Central New JerseyNCT06745999Written as Ameluz 10% Topical Gel
- PDT Plus Vitamin D3 for Anal DysplasiaWithdrawnPhase 1Abramson Cancer Center at Penn MedicineNCT02698293Written as Gliolan
- ALA-induced PpIX Fluorescence During Brain Tumor ResectionActive, not recruitingPhase 1David W. RobertsNCT02191488Written as 5-aminolevulinic acid
- Impact of PDT and Topical Corticosteroids on Taste Perception and Salivary Oxidative Stress Markers in Patients With OLPCompletedNot applicableMedical University of BialystokNCT07536737Written as 5-Amino Levulinic Acid
- Photodynamic Therapy for Benign Dermal Neurofibromas- Phase IITerminatedPhase 2Donald BaselNCT02728388Written as aminolevulinic acid
- PD L 506 for Stereotactic Interstitial Photodynamic Therapy of Newly Diagnosed Supratentorial IDH Wild-type GlioblastomaTerminatedPhase 2photonamic GmbH & Co. KGNCT03897491Written as 5-aminolevulinic acid
See all 108 studies that test Aminolevulinic Acid →
Given in every arm · 4 — Aminolevulinic Acid is usual care beside what is tested
- Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal CancerRecruitingPhase 1/2Roswell Park Cancer InstituteNCT06307548Written as Aminolevulinic Acid
- Photodynamic Therapy in Treating Patients With Refractory Mycosis FungoidesCompletedEarly Phase 1Mayo ClinicNCT03281811Written as Aminolevulinic Acid Hydrochloride
- The Use of Microneedles in Photodynamic TherapyCompletedNot applicableUniversity of California, DavisNCT01812837Written as Aminolevulinic Acid
- Pain Relief During Photodynamic Therapy for Actinic Keratoses With a New Irradiation ProtocolCompletedNot applicableVastra Gotaland RegionNCT02644187Written as BF200-ALA/5-aminolevulinic acid
As the comparator · 1 — what is tested is compared with Aminolevulinic Acid
Codes
What other systems call Aminolevulinic Acid · ClinicalTrials.gg INT006952
- MeSH (NLM) D000622Aminolevulinic AcidConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 88755TAZ87AMINOLEVULINIC ACIDConfirmed FDA, NLM, Wikidata
- RxNorm 683Confirmed FDA, Wikidata
- Wikidata Q238474aminolevulinic acidConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C234Aminolevulinic AcidOne source FDA
- DrugBank DB00855One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000622 | Aminolevulinic Acid | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 88755TAZ87 | AMINOLEVULINIC ACID | Confirmed FDA, NLM, Wikidata |
| RxNorm | 683 | — | Confirmed FDA, Wikidata |
| Wikidata | Q238474 | aminolevulinic acid | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C234 | Aminolevulinic Acid | One source FDA |
| DrugBank | DB00855 | — | One source Wikidata |
Also registered as aminolevulinic acid hydrochloride (UNII V35KBM8JGR · RxNorm 261715).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.