Skin Neoplasms clinical trials
The registry lists 604 studies for Skin Neoplasms across more than 10 countries. 126 are recruiting or about to start. 253 of them are mainly about Skin Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 7 narrower conditions too, such as Melanoma: 4,007 studies, 709 open.
ClinicalTrials.gov finds 19,561 studies for Skin Neoplasms. How that becomes 605 here
This page counts the studies the registry files under Skin Neoplasms, and those it files under no condition that list Skin Neoplasmsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 19,561Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −3,058Filed under a narrower condition, counted on its own pageMelanoma 2,991 · Blastic Plasmacytoid Dendritic Cell Neoplasm 45 · Basal Cell Nevus Syndrome 10 · Dysplastic Nevus Syndrome 5 · Uveal Melanoma 5
- −49List Skin Neoplasms as a condition, but the registry did not file them under itMost often written as “Non-melanoma Skin Cancer” (14), “Non-melanomatous Skin Cancer” (13), and “Skin Cancer Face” (6). The registry filed them under other conditions only, most often Carcinoma, Basal Cell (22) and Keratosis, Actinic (8).
- −15,849Match it another way52 name it in the title, 12 in a keyword, and 15,785 by a synonym or other text the search reads.
- 605The count on this page41 of them list Skin Neoplasms in their own words; the registry filed them under no condition.
Get an email when these change. Save the Skin Neoplasms studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Cancer Institute (NCI) (33) · H. Lee Moffitt Cancer Center and Research Institute (19) · M.D. Anderson Cancer Center (12) · Massachusetts General Hospital (11) · Alpha Tau Medical LTD. (11) · Memorial Sloan Kettering Cancer Center (11) · Northwestern University (10) · Stanford University (10)
What is being tested here
Drugs under test in Skin Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cemiplimab | 6 | 1 | 9 |
| Nivolumab | 3 | 1 | 7 |
| Ipilimumab | 2 | 1 | 8 |
| Pembrolizumab | 2 | 0 | 5 |
| Lifileucel | 2 | 1 | 3 |
| Niacinamide | 2 | 0 | 2 |
| Aminolevulinic Acid | 1 | 0 | 6 |
| HhAntag691 | 1 | 0 | 3 |
| Cosibelimab | 1 | 0 | 2 |
| Suzetrigine | 1 | 0 | 1 |
Drug classes tested here Immune checkpoint inhibitors 12 open · Antimitotic agents 1 open · Tyrosine kinase inhibitors (TKIs) 17 · Alkylating agents 9 · Antimetabolites 7
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jan 2027A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery · Phase 3 · Regeneron Pharmaceuticals
- Mar 2027Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma · Phase 3 · TuHURA Biosciences, Inc.
- Sep 2027Undergraduate Skin Cancer Prevention Trial · Phase 3 · University of Utah
- Sep 2027Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin) · Phase 3 · Melanoma and Skin Cancer Trials Limited
- Nov 2026Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome · Centre Hospitalier Universitaire de Nīmes
- Nov 2026Assessment of Skin Lesions Using a Tissue Oxygen Imager Based on Protoporphyrin IX (PPIX) Fluorescence. This is an Open-label, Non-randomized, Feasibility Study That Includes a One-time Application of an FDA Approved Medication Followed by Local Imaging for Benign Skin Growth and Lesions Clinically · Dartmouth-Hitchcock Medical Center
- Nov 2026A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma · Regeneron Pharmaceuticals
- Dec 2026Liquid Biomarker Study in Melanoma and Non-Melanoma Skin Cancers · University of Wisconsin, Madison
- Dec 2026Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT) · Alpha Tau Medical LTD.
- Dec 2026In Vivo Confocal Microscopy of Cutaneous Neoplasms and Normal Skin · Memorial Sloan Kettering Cancer Center
Who these studies take
Of the 104 Skin Neoplasms studies recruiting now, 84 (81%) set no upper age limit and 9 (9%) stop at 75 or younger. 15 (14%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 25 (24%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 10 (10%) | 9 (9%) |
| 18 | 99 (95%) | 98 (94%) |
| 30 | 100 (96%) | 99 (95%) |
| 40 | 100 (96%) | 99 (95%) |
| 50 | 99 (95%) | 99 (95%) |
| 65 | 98 (94%) | 98 (94%) |
| 75 | 95 (91%) | 95 (91%) |
| 85 | 94 (90%) | 94 (90%) |
Across all 604 studies, recruiting or not: 10% stop at 75 or younger and 6% at 65; 15% take children; 2% are for women only and 1% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Skin Neoplasms studies take
Of 36 phase 1 interventional studies under Skin Neoplasms, half reached primary completion within 49 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 49 mo28–57 · 36 studies | — | — |
| Phase 2 | 60 mo35–97 · 34 studies | — | — |
| Interventional, no phase | 27 mo10–66 · 116 studies | — | 23 mo9–49 · 94 studies |
| Observational | 72 mo21–248 · 78 studies | — | 139 mo24–… · 53 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Stopped2
- Study to Evaluate JCXH-211 as Monotherapy in Patients With Malignant Solid TumorsTerminatedNov 5, 2026NCT05539157
- Digital Phenotyping of Psychological Distress in Skin Cancer PatientsWithdrawnOct 16, 2026NCT07670403
Newly registered2
- Patient-Controlled Ambient Light to Reduce Pre-Visit Anxiety in Dermatology PatientsOct 26, 2026NCT07896122
- Cemiplimab and Quad Shot Radiation for Cutaneous Squamous Cell Carcinoma in the Head and NeckOct 13, 2026NCT07869823
Studies
Recruiting first, then most recently updated. Showing 50 of 604. Browse all 604 → or search them.
- Blocking TNF to Potentiate the ICI-dependent Immune Awakening in MelanomaRecruitingNCT058670041 country
- Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local ExcisionNot yet recruitingNCT07844681Not applicable1 country
- Neoadjuvant Merkel Cell Carcinoma Therapy (Tx) With the PD-1 Inhibitor CemiplimabRecruitingNCT07387198Phase 21 country
- A Multilevel Approach to Connecting Underrepresented Populations to Clinical TrialsRecruitingNCT056554941 country
- Evaluation of Efficacy and Safety of Cemiplimab as First Line Treatment for Advanced Basal Cell Carcinoma (BCC) PatientsRecruitingNCT06981325Phase 21 country
- Early Detection of Skin Tumors Using a Telemedicine Tool in Primary CareRecruitingNCT07349940Not applicable1 country
- Safety and Efficacy of OBX-115 in Advanced Solid TumorsRecruitingNCT06060613Phase 1/22 countries
- A Study Comparing Cemiplimab-based Treatments for Adult Participants With Locally Advanced Basal Cell Skin Cancer (laBCC)Not yet recruitingNCT07808515Phase 2
- Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of MelanomaRecruitingNCT000403521 country
- Regional Efforts to Advance School-based Sun Safety Through Collaboration for Skin HealthEnrolling by invitationNCT07904572Not applicable1 country
- A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative ExcisionRecruitingNCT06664151Early Phase 11 country
- Implementation of Teledermoscopy and Artificial IntelligenceRecruitingNCT050336781 country
- Cemiplimab and Quad Shot Radiation for Cutaneous Squamous Cell Carcinoma in the Head and NeckRecruitingNCT07869823Early Phase 11 country
- Skin Subs vs Secondary IntentionNot yet recruitingNCT07587749Phase 41 country
- E-MOHS Trial of TENS and Vibration During Local AnesthesiaNot yet recruitingNCT07852455Not applicable1 country
- Suzetrigine Versus Standard Analgesia After Skin Cancer SurgeryNot yet recruitingNCT07843134Phase 41 country
- Developing and Testing the Effectiveness of a Skin Cancer Self-Detection Educational ProgramRecruitingNCT07247123Not applicable1 country
- Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.RecruitingNCT05727904Phase 316 countries
- Mobile Sun Health Intervention EnabLing Daily ProtectionRecruitingNCT07830394Not applicable1 country
- Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible SensitivityRecruitingNCT04273061Phase 21 country
- Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell CarcinomaRecruitingNCT06585410Phase 32 countries
- The Effect of Reduced Bleomycin in Electrochemotherapy TreatmentRecruitingNCT06647342Phase 41 country
- iSCIB1+ in Combination With Ipilimumab and Nivolumab as First-Line Treatment for Advanced Unresectable MelanomaNot yet recruitingNCT07815574Phase 32 countries
- Minibeam Radiation Therapy With Tungsten Slit Collimator for the Treatment of Recurrent or Metastatic Skin or Soft Tissue TumorsRecruitingNCT07062003Not applicable1 country
- Lower Extremity Graft Study (LEGS): A Multicentre Randomised Controlled Trial of Negative Pressure Wound Therapy Versus Conventional Dressings for Split-thickness Skin Grafts After Lower Leg Skin Tumour ExcisionRecruitingNCT07040683Not applicable1 country
- Cryoablation+Ipilimumab+Nivolumab in MelanomaRecruitingNCT05779423Phase 21 country
- Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome.RecruitingNCT049041461 country
- A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of PembrolizumabRecruitingNCT02621021Phase 21 country
- High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO TrialRecruitingNCT06298734Not applicable1 country
- A Study to Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Unresectable or Metastatic Melanoma Participants In IndiaNot yet recruitingNCT07459543Phase 41 country
- A First-in-Human Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of KUP-101A in Patients With Selected Advanced Solid TumorsRecruitingNCT07600476Phase 11 country
- A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor CancerRecruitingNCT05859074Phase 11 country
- Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic MalignancyRecruitingNCT07426484Phase 41 country
- Rural Adult and Youth Sun Protection StudyRecruitingNCT06439979Not applicable1 country
- Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant AppRecruitingNCT066756431 country
- Sun Safe Together: A Digital Skin Cancer Prevention Intervention for Adolescents and Their ParentsRecruitingNCT07681791Not applicable1 country
- Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer HospitalNot yet recruitingNCT07606287Not applicable1 country
- The Florida ASCENT StudyRecruitingNCT07042243Not applicable1 country
- DNA Repair Activity in the Skin of Day and Night Shift WorkersRecruitingNCT04122456Not applicable1 country
- Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous SCC for Immunocompromised PatientsRecruitingNCT06615635Not applicable2 countries
- AI-Based Risk Classification and Histopathological Subtype Prediction of Basal Cell Carcinoma Using Dermoscopic ImagesRecruitingNCT076771241 country
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT020126991 country
- Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)RecruitingNCT073274891 country
- Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational StudyRecruitingNCT072159881 country
- Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell CarcinomaRecruitingNCT04975152Phase 11 country
- Optical Characterization and Multi-modality, Multi-scale Modeling of Human Skin Applied to Cancer Diagnosis.RecruitingNCT074060221 country
- Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch SyndromeRecruitingNCT07201012Not applicable1 country
- The Application of Infrared Thermography in the Prediction of Skin Healing in SurgeryRecruitingNCT07524062Not applicable1 country
- Alpha Radiation Emitters Device (DaRT) for the Treatment of of Malignant Cutaneous TumorsRecruitingNCT04068155Not applicable1 country
- Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue NeoplasiaRecruitingNCT04534127Not applicable1 country