Drug
Methyl aminolevulinate clinical trials
Also written Metvix.
Includes 2 studies of Methyl aminolevulinate hydrochloride.
- studies test it
- 19
- open now
- 0
- in phase 3
- 7
- first study started
- 1999
How studies write it
Studies that test it under each name
Name
Brand
Development codes
Other names
Combined with it in one product
Studies by the year they started
19 studies that test it; most in 2015 (3)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2000 | 2 |
| 2006 | 1 |
| 2007 | 1 |
| 2008 | 2 |
| 2009 | 1 |
| 2012 | 1 |
| 2013 | 2 |
| 2014 | 2 |
| 2015 | 3 |
| 2016 | 1 |
| 2017 | 1 |
| 2019 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 1
- Phase 2
- 3
- Phase 3
- 7
- Phase 4
- 6
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 11
Galderma R&D (5) · Maastricht University Medical Center (2) · Biofrontera Bioscience GmbH (2) · Joint Authority for Päijät-Häme Social and Health Care (2) · Norwegian University of Science and Technology (1) · Centre Hospitalier Universitaire de Nīmes (1) · Fundación Dermabase (1) · Innovaderm Research Inc. (1)
Often tested with
Tested in the same studies.
BF-200 ALA (3) · Aminolevulinic Acid (2) · Fluorouracil (1) · Hexaminolevulinate hydrochloride (1)
Studies
Open first, then newest update. How each study uses methyl aminolevulinate is read from its arms, and is right about nine times in ten.
Testing it · 19
- Surgical Excision Versus Photodynamic Therapy and Topical 5-fluorouracil in Treatment of Bowen's DiseaseCompletedPhase 4Maastricht University Medical CenterNCT03909646Written as Methyl Aminolevulinate (Mal) for Topical Administration, 16.8%, 1 Gram
- Metvix Photodynamic Therapy (PDT) Versus Cryotherapy in Participants With Primary Superficial Basal Cell CarcinomaCompletedPhase 3Galderma R&DNCT00469417Written as Metvix® cream
- Photodynamic Therapy (PDT) With Metvix Cream 160 mg/g Versus PDT With Placebo Cream in Participants With Primary Nodular Basal Cell CarcinomaCompletedPhase 3Galderma R&DNCT00472108Written as Metvix cream
- Comparison of Metvix Photodynamic Therapy (PDT) With Its Vehicle in the Treatment of Photoaged SkinCompletedPhase 2Galderma R&DNCT00437320Written as Metvix Cream 160 mg/g
- Metvix PDT in Participant With "High Risk" Basal Cell CarcinomaCompletedPhase 3Galderma R&DNCT00473343Written as Metvix® cream
- Safety and Efficacy Study for the Treatment of Non-Aggressive Basal Cell Carcinoma With Photodynamic TherapyCompletedPhase 3Biofrontera Bioscience GmbHNCT02144077Written as methyl-aminolevulinate
- PRO With Luxerm® in the Field Treatment of Thin and Non-hyperkeratotic Non-pigmented AKCompletedPhase 4Galderma R&DNCT03511326Written as Methyl Aminolaevulinate 16% Cream
- Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL)CompletedPhase 4Joint Authority for Päijät-Häme Social and Health CareNCT02464709Written as Methyl 5-aminolevulinate
- New Versus Approved Methyl-aminolevulinate Photodynamic Therapy (MAL-PDT) Regime in Basal Cell Carcinoma (BCC)CompletedNot applicableNorwegian University of Science and TechnologyNCT01482104Written as MAL-PDT re-treatment
- Evaluation of Safety and Efficacy of BF-200 ALA for the Treatment of Actinic Keratosis With Photodynamic TherapyCompletedPhase 3Biofrontera Bioscience GmbHNCT02799069Written as MAL Cream
- Daylight Photodynamic Therapy for Actinic Keratosis and Skin Field CancerizationStatus unknownNot applicableUniversity of Sao Paulo General HospitalNCT03013647Written as Methyl Aminolevulinate
- Daylight-PDT for AKs: Comparing Two Photosensitizers (BF-200 ALA and MAL)CompletedPhase 4Joint Authority for Päijät-Häme Social and Health CareNCT01893203Written as MAL cream
- Effects of Topical Dynamic Phototherapy on the Microbiota of Chronic WoundsCompletedNot applicableCentre Hospitalier Universitaire de NīmesNCT02392390Written as Metvixia cream
- Efficacy and Safety of Treatment of Actinic Keratoses With Photodynamic Therapy Between MAL Cream and ALA GelStatus unknownPhase 4Fundación Instituto Valenciano de OncologíaNCT02647151Written as METHYLAMINOLEVULINATE HYDROCHLORIDE
- Efficacy of Methyl Aminolevulinate + Daylight in Patients With Facial PhotodamageCompletedPhase 2Fundación DermabaseNCT02139618Written as Methyl Aminolevulinate (MAL)
- Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage MethylaminolevulinateStatus unknownPhase 4Maastricht University Medical CenterNCT01491711Written as Methylaminolevulinate PDT in 2 sessions
- Short Incubation Methylaminolevulinate Photodynamic Therapy Without OcclusionCompletedPhase 3Innovaderm Research Inc.NCT00926952Written as Methylaminolevulinate (Metvix, Metvixia)
- A Dose-finding Study of MAL and HAL Photodynamic Therapy of Cervical Premalignant Lesions.CompletedPhase 1/2PhotocureNCT00369018Written as methyl aminolevulinate (MAL) and hexaminolevulinate (HAL)
- Trial of Methyl Aminolevulinate Plus Aktilite in Facial PhotodamageCompletedPhase 3Universidad de AntioquiaNCT00629317Written as Methyl Aminolevulinate
Given in every arm · 4 — methyl aminolevulinate is usual care beside what is tested
- Actinic Keratoses Treatment With Metvix® in Combination With LightCompletedPhase 3University Hospital, LimogesNCT02373371Written as Metvix®
- New Treatments for Actinic Keratoses of the ScalpActive, not recruitingNot applicableHelsinki University Central HospitalNCT05456334Written as Metvix cream
- Laser Assisted Drug Delivery in the Treatment of Superficial Non Melanoma Skin Cancer: a Randomized Controlled TrialCompletedNot applicableUniversity Hospital, GhentNCT03012009Written as MAL
- Photodynamic Therapy Using Methyl-5-Aminolevulinate Hydrochloride Cream in Determining Pain Threshold in Patients With Skin CancerCompletedPhase 1Roswell Park Cancer InstituteNCT01292668Written as methyl-5-aminolevulinate hydrochloride cream
As the comparator · 2 — what is tested is compared with methyl aminolevulinate
- Comparison of Mechanical Penetration Enhancers on Metvixia Skin PenetrationCompletedPhase 1Galderma R&DNCT02511145Written as METVIXIA Cream
- Superficial Basal Cell Cancer's Photodynamic Therapy: Comparing Three Photosensitizers: HAL and BF-200 ALA Versus MALActive, not recruitingPhase 1/2Joint Authority for Päijät-Häme Social and Health CareNCT02367547Written as Methylaminolevulinate cream
Codes
What other systems call methyl aminolevulinate · ClinicalTrials.gg INT004537
- MeSH (NLM) C475457methyl 5-aminolevulinateConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 585NM85KYMMETHYL AMINOLEVULINATEConfirmed FDA, NLM, Wikidata
- RxNorm 337068Confirmed FDA, Wikidata
- Wikidata Q619603methyl aminolevulinateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C76305Methyl AminolevulinateOne source FDA
- DrugBank DB00992One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C475457 | methyl 5-aminolevulinate | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 585NM85KYM | METHYL AMINOLEVULINATE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 337068 | — | Confirmed FDA, Wikidata |
| Wikidata | Q619603 | methyl aminolevulinate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C76305 | Methyl Aminolevulinate | One source FDA |
| DrugBank | DB00992 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.