Adrenergic alpha-Agonists: all 451 studies that test it

Page 4 of 5. Open to participants first (88), then studies with results posted, then the rest; newest registration first within each.

• Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in PhacoemulsificationStatus unknownNCT03638726Phase 4
• Norepinephrine Addition in Spinal Anesthesia of Caesarean SectionCompletedNCT03626454Not applicable
• Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and LaryngoscopyCompletedNCT03620513Phase 4
• Nebulized Hypertonic Saline (3%) Versus Nebulized Adrenaline for Treatment of BronchiolitisCompletedNCT03614273Not applicable
• Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone StudyCompletedNCT03567473Phase 3
• Intra-anal Oxymetazoline in Healthy Adult VolunteersStatus unknownNCT03529487Phase 1
• Peri-Incisional Drug Injection in Lumbar Spine SurgeryWithdrawnNCT03513445Phase 3
• Effect of Local Infiltration Anesthesia in a Hip Arthroplasty Fast Track Program.CompletedNCT03513276Phase 4
• The Effects of Nasal Airflow on Upper Airway Dilator Muscles During SleepStatus unknownNCT03506178Not applicable
• Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic TreatmentWithdrawnNCT03502135Phase 4
• A Study of the Effect of Epinephrine on Platelet Reactivity in Subjects Treated With TicagrelorCompletedNCT03441412Phase 1
• Anterior Ethmoidal Nerve Block in Prevention of Postoperative AgitationCompletedNCT03427502Not applicable
• : Pulpal Blood Flow With the Use of Intra-nasal AnestheticStatus unknownNCT03368391Phase 4
• Norepinephrine vs Norepinephrine and Dobutamine in Cardiogenic ShockStatus unknownNCT03340779Phase 3
• RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections.WithdrawnNCT03335293Phase 4
• Norepinephrine Versus Phenylephrine Continuous Variable Infusion in Cesarean DeliveryCompletedNCT03328533Phase 4
• Norepinephrine for Spinal-induced HypotensionStatus unknownNCT03308708Not applicable
• Effects of Intraoperative, Goal-directed Crystalloid vs. Colloid Fluid Resuscitation on Free FlapsCompletedNCT03288051Not applicable
• Vasopressor Infusion in Cesarean DeliveryStatus unknownNCT03248791Phase 4
• Transversalis Fascia Plane Blocks for Analgesia Post-cesarean DeliveryCompletedNCT03236324Phase 2
• Vasopressor Prophylaxis After Spinal AnesthesiaCompletedNCT03234816Phase 4
• Phenylephrine or Norepinephrine for a Better Hemodynamic StabilityCompletedNCT03215797Phase 3
• The Effect of Popliteal Plexus Block on Pain After Total Knee ArthroplastyCompletedNCT03198403Phase 4
• Norepinephrine Infusion Different Doses in Cesarean DeliveryCompletedNCT03182088Phase 4
• Effect of Vasopressors on Spinal Anaesthesia Induced HypotensionCompletedNCT03163914Phase 4
• Norepinephrine Versus Ephedrine in Treatment of Hypotension During Spinal Anesthesia for Caesarean SectionCompletedNCT03163407Not applicable
• Effect of Topical and Systemic Tranexemic Acid on Bleeding During Ear Exploration SurgeryStatus unknownNCT03112135Phase 2
• The Effect of Norepinephrine Versus Dopamine in Renal Transplant Recipients on Postoperative Graft FunctionStatus unknownNCT03107858Phase 2/3
• Small Doses of Pituitrin Versus Norepinephrine for the Management of Vasoplegic Syndrome in Patients After Cardiac SurgeryStatus unknownNCT03106831Not applicable
• VATS Block for Uniportal Video-assisted Thoracoscopic SurgeryStatus unknownNCT03083080Not applicable
• Blood Pressure During ESD is Related With the Postoperative BleedingStatus unknownNCT03070665Not applicable
• Efficacy of External Nasal Nerve Block in Prevention of Postoperative Agitation Following Nasal SurgeriesCompletedNCT03069027Not applicable
• Postoperative Analgesia After Elective Hip Surgery - Effect of Obturator Nerve BlockadeCompletedNCT03064165Phase 4
• The Pectoral Block for Breast Augmentation SurgeryCompletedNCT03040167Phase 4
• Phenylephrine and Noradrenaline for Post Spinal Anesthesia HypotensionCompletedNCT03015857Phase 2
• Optimal Timing of Intercostal Nerve Blocks During Video-Assisted Thoracic SurgeriesCompletedNCT02980835Phase 4
• Norepinephrine and Phenylephrine for Maternal Cardiac Output During Spinal Anesthesia for Elective Cesarean DeliveryStatus unknownNCT02969239Phase 4
• A Comparison of Intermittent Intravenous Boluses of Phenylephrine and Norepinephrine to Prevent Spinal-induced Hypotension in Cesarean DeliveriesCompletedNCT02962986Not applicable
• Epinephrine Sprayed on the Papilla Versus Sterile Water Sprayed on the Papilla for Preventing Pancreatitis After Endoscopic Retrograde CholangiopancreatographyTerminatedNCT02959112Not applicable
• The Effects of Low-dose Epinephrine Plus Tranexamic Acid on Perioperative Haemostasis and Inflammatory Reaction in Major SurgeryStatus unknownNCT02864095Not applicable
• Intravenous Versus Topical Administration of Low Dose Epinephrine Plus Combined Administration of Intravenous and Topical Tranexamic Acid (TXA)for Primary Total Knee ArthroplastyStatus unknownNCT02860221Not applicable
• Intravenous Bolus of Phenylephrine vs. Norepinephrine in Preventing Hypotension After Spinal AnesthesiaCompletedNCT02854787Phase 4
• Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP PancreatitisStatus unknownNCT02839356Phase 4
• Changes in Measured Plasma Volume, Glycocalyx and Atrial Natriuretic Peptide During AnaesthesiaCompletedNCT02832596Not applicable
• Outcomes of Renal Function in Hepatorenal Syndrome (HRS) Determined By Comparison of Target Mean Arterial Pressure (MAP) of 65 - 70 Mmhg Versus ≥ 85 MmhgCompletedNCT02789150Early Phase 1
• Cardiac Output Changes in Cesarean SectionStatus unknownNCT02759510Early Phase 1
• Furosemide Stress Test Guiding Initiation of Renal Replacement TherapyCompletedNCT02730117Not applicable
• Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and FusionStatus unknownNCT02724761Not applicable
• The Effect of Subsartorial Saphenous Block on Postoperative Pain Following Major Ankle and Hind Foot SurgeryCompletedNCT02697955Phase 4
• Dose Response of EpinephrineCompletedNCT02692313Early Phase 1
• Effects of Vasopressors on Immune ResponseCompletedNCT02675868Phase 4
• Norepinephrine To Prevent Hypotension After Spinal Anesthesia For Cesarean Delivery: A Dose Finding StudyCompletedNCT02654847Not applicable
• Effects of Levosimendan, Milrinone and Norepinephrine on Left and Right Ventricular Function in Septic ShockStatus unknownNCT02640846Phase 4
• Study of Multistep Pharmacological and Invasive Management for Cardiogenic ShockCompletedNCT02591771Phase 2
• Epinephrine, Dexamethasone and Hypertonic Saline in BronchiolitisStatus unknownNCT02585531Phase 2
• To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver FailureCompletedNCT02573727Not applicable
• Pain Management Following Total Hip ArthroplastyCompletedNCT02568995Phase 3
• Mometasone Furoate and Oxymetazoline in the Treatment of Adenoid HypertrophyCompletedNCT02559440Phase 4
• Comparison of Norepinephrine and Ephedrine on Hypotension After Spinal Anesthesia in ParturientsCompletedNCT02542748Not applicable
• Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee ArthroplastyStatus unknownNCT02540070Phase 3
• Microcirculation After MAP Increase in Septic Shock Patients With Previous HypertensionCompletedNCT02519699Phase 4
• Weaning of Norepinephrine Guided by the Dynamic Arterial Compliance in Cardiac Surgery Post Operative.CompletedNCT02479529Phase 3
• Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean SectionCompletedNCT02477501Phase 4
• Implementation of a Pain Management Protocol for Total Knee ArthroplastyCompletedNCT02474654Phase 4
• Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic ShockCompletedNCT02473263Phase 3
• Renal Perfusion, Filtration and Oxygenation After Liver Transplantation -Effects of av Postoperative Blood PressureCompletedNCT02455115Not applicable
• The Effect of the Serratus Block on Pain Control After Breast SurgeryCompletedNCT02453516Phase 2/3
• Anisodamine Critically Ill SeptIc ShockCompletedNCT02442440Phase 1/2
• Target Hemodynamics and Brain Injury During General Anesthesia in the ElderlySuspendedNCT02428062Phase 2/3
• Liposomal Bupivacaine in Total Knee ArthroplastyWithdrawnNCT02426164Phase 4
• Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible PulpitisCompletedNCT02422823Not applicable
• Pressure-dependent Changes in Hematocrit and Plasma Volume During AnesthesiaStatus unknownNCT02412189Not applicable
• Adductor Canal Block and Recovery After Total Knee Replacement SurgeryCompletedNCT02411149Phase 4
• Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical ConizationCompletedNCT02368054Phase 4
• The Effect of Oxymetazoline Gel on Anal Pressure and Incontinence in Spinal Cord Injury PatientsCompletedNCT02299557Phase 1/2
• Post-Caesarean Section Incisional Infiltration With Lidocaine Versus Lidocaine and EpinephrineCompletedNCT02274974Phase 4
• Safety and Efficacy of Cocktail Periarticular Injection in Simultaneous Total Knee ArthroplastyCompletedNCT02270437Phase 4
• Hemostasis During Hypospadias SurgeryStatus unknownNCT02268019Not applicable
• The Effect of Norepinephrine and Dopamine on Radial Forearm Free Flap Tissue Oxygen Pressure and Microdialysate Metabolite MeasurementsCompletedNCT02241083Phase 4
• Dental Anesthesia in Heart Failure PatientsStatus unknownNCT02228083Not applicable
• Study to Assess the Effects of Allergic Rhinitis and Co-administration of Mometasone or Oxymetazoline on the Pharmacokinetics, Safety, and Tolerability of Intranasal EsketamineCompletedNCT02154334Phase 1
• Effect of Dexamethasone and Epinephrine on the Duration of Sciatic Nerve Blocks With RopivacaineStatus unknownNCT02104778Not applicable
• Effect of Different Strategies for Titrating a High MAP on MicrocirculationCompletedNCT02085291Phase 4
• Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline AbsorptionWithdrawnNCT02062996Phase 2
• Impact of Cardiac Blood Flow on Cerebral Blood Flow in Patients With Severe Traumatic Brain InjuryStatus unknownNCT02019810Phase 2
• The Effect of Topical Administration of Common Drugs on Postoperative Bleeding and PainCompletedNCT01964781Phase 4
• Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.CompletedNCT01964586Phase 4
• TransMEM Gas Exchange -- Project 1, Aim 2CompletedNCT01925729Phase 1
• Anesthetic Efficacy of Articaine and Lidocaine in Lower Molars With Irreversible PulpitsCompletedNCT01912755Phase 4
• Comparative Evaluation of Handling Characteristics of Two Adrenaline Autoinjectors,EpiPen in Comparison With JextCompletedNCT01887405Phase 4
• Vasopressin Versus Epinephrine in MyomectomyCompletedNCT01861015Phase 3
• The Effect of Nasal Hair on Nasal ObstructionCompletedNCT01850511Not applicable
• Epinephrine, Dexamethasone, and Hypertonic Saline in Bronchiolitis, Randomised Clinical Trial of Efficacy and SafetyCompletedNCT01834820Phase 4
• Effect of Fentanyl on the Rate of AnesthesiaCompletedNCT01794533Phase 2
• Sciatic Nerve Block for Ankle/Foot Surgeries. A Comparison Between a Premixed Solution of Lidocaine Plus Bupivacaine and Consecutive Infiltration of Lidocaine and BupivacaineCompletedNCT01756443Phase 4
• Vasopressin Versus Norepinephrine for the Management of Septic Shock in Cancer PatientsCompletedNCT01718613Phase 3
• The Effect of Administration of Low Dose Adrenaline During Surgery on Bleeding During Hip SurgeryCompletedNCT01708642Phase 3
• The Effect and Safety of Low Dose Nebulized Epinephrine in CroupStatus unknownNCT01664507Phase 4
• To Compare the Efficacy of Nor Adrenaline and Terlipressin vs Step up Terlipressin Therapy in Hepatorenal SyndromeWithdrawnNCT01649037Not applicable
• TYPE 2 HEPATORENAL SYNDROMECompletedNCT01637454Phase 3

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