Drug
Acyclovir clinical trials
Also written Zovirax and Aciclovir.
- studies test it
- 62
- open now
- 6
- in phase 3
- 21
- first study started
- 1992
Keep track of what changes. Save the Acyclovir studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Other names
Combined with it in one product
Studies by the year they started
48 studies that test it; most in 2024 (5)
| Year | Studies |
|---|---|
| 1992 | 2 |
| 1995 | 1 |
| 1997 | 3 |
| 1999 | 1 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 4 |
| 2006 | 3 |
| 2008 | 3 |
| 2009 | 2 |
| 2010 | 1 |
| 2011 | 2 |
| 2012 | 2 |
| 2014 | 3 |
| 2015 | 2 |
| 2017 | 2 |
| 2018 | 1 |
| 2019 | 2 |
| 2020 | 2 |
| 2021 | 1 |
| 2022 | 2 |
| 2024 | 5 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 6
- Phase 2
- 11
- Phase 3
- 21
- Phase 4
- 12
- No phase
- 17
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 12 · Other 50
National Institute of Allergy and Infectious Diseases (NIAID) (11) · University of Washington (6) · Glaxo Wellcome (5) · National Center for Research Resources (NCRR) (4) · Genzyme, a Sanofi Company (2) · Centers for Disease Control and Prevention (2) · Fred Hutchinson Cancer Center (2) · Bayer (1)
Often tested with
Tested in the same studies.
Zidovudine (4) · Valacyclovir (4) · Ganciclovir (3) · Methylprednisolone (2) · Acetaminophen (2) · Cetirizine (2) · Dexchlorpheniramine (2) · Chlorpheniramine (2)
Studies
Open first, then newest update. How each study uses Acyclovir is read from its arms, and is right about nine times in ten.
Testing it · 62
- Prevention of Recurrence of Herpes Simplex in Autoimmune Rheumatic DiseasesRecruitingPhase 4University of Sao Paulo General HospitalNCT07341386Written as Acyclovir (ACV)
- Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BALRecruitingPhase 3Jena University HospitalNCT06134492Written as Acyclovir
- Individualization of Dosage Regimens in Obese Patients: Application to AcyclovirRecruitingPhase 1University Hospital, ToulouseNCT05589688Written as Acyclovir
- Aciclovir Versus Placebo for HSV-2 MeningitisNot yet recruitingPhase 4Jacob BodilsenNCT05452928Written as Acyclovir 50 MG/ML
- The Bioequivalence Study of Acyclovir 800 mg Tablet in Healthy Thai Volunteers Under Fasting ConditionsNot yet recruitingPhase 1International Bio serviceNCT06228430Written as Acyclovir 800 mg Tablet
- Preemptive Treatment With Acyclovir in Intubated and Mechanically Ventilated Patients With Herpes (PTH2)Not yet recruitingNot applicableAssistance Publique - Hôpitaux de ParisNCT06217406Written as Intravenous acyclovir (ACYCLOVIR )
- A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMTTerminatedPhase 3Genzyme, a Sanofi CompanyNCT03368664Written as Acyclovir
- A Study to Compare Sitavig (Acyclovir) Buccal Tablet With a Placebo in the Treatment of Herpes Labialis in Participants Whose Immune System Works NormallyCompletedPhase 3BayerNCT05098938Written as Acyclovir 50mg buccal/topical tablet, BAYM008894/UI1614773
- Topical Ganciclovir Versus Systemic Aciclovir in the Treatment of Herpetic KeratitisCompletedNot applicableAl-Azhar UniversityNCT06757907Written as Acyclovir 400 MG
- Comparison of Prophylactic Acyclovir and Placebo in Prevention of Eczema Herpeticum in Pediatric BurnsCompletedNot applicableKing Edward Medical UniversityNCT06380647Written as Intravenous Acyclovir
- PTH - Preemptive Treatment for HerpesviridaeCompletedPhase 4Assistance Publique Hopitaux De MarseilleNCT02152358Written as Aciclovir
- Effect of HSV-2 Suppressive Therapy on Sexual BehaviorTerminatedPhase 4University of WashingtonNCT00495716Written as acyclovir
- Pharmacokinetic Properties of 200 and 400 mg Acyclovir Tablet in Indonesia Healthy SubjectCompletedNot applicablePT. Kimia Farma (Persero) TbkNCT04988646Written as Acyclovir 200 MG
- Intralesional Injection of Acyclovir Versus Candida Antigen in Treatment of Plantar WartsStatus unknownPhase 4Sohag UniversityNCT05429151Written as Acyclovir 250mg Powder for Solution for Infusion, each vial contains 250mg of acyclovir as the sodium salt, Chandra Bhagat Pharma Pvt. Ltd andcandida antigen
- Intralesional Vitamin D3 Versus Intralesional Acyclovir in Treatment of Plantar WartsStatus unknownNot applicableAssiut UniversityNCT05324904Written as acyclovir
- Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) KeratitisWithdrawnPhase 4NYU Langone HealthNCT03626376Written as oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily
- Randomized Trial to Evaluate Suppressive Effect of High-Dose Acyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2CompletedPhase 4University of WashingtonNCT00362297Written as acyclovir
- A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3CompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000712Written as Acyclovir
- A Study of Zidovudine Plus Acyclovir in HIV-Infected PatientsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT00001010Written as Acyclovir
- Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients With AIDS Who Have Not Had Success With AcyclovirCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00000985Written as Acyclovir
See all 62 studies that test Acyclovir →
Given in every arm · 12 — Acyclovir is usual care beside what is tested
- A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular DegenerationRecruitingPhase 1Astellas Institute for Regenerative MedicineNCT03178149Written as Acyclovir
- Carfilzomib, Rituximab, and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell LymphomaCompletedPhase 1/2Case Comprehensive Cancer CenterNCT02073097Written as Acyclovir
- Letermovir Versus Valganciclovir to Prevent Human Cytomegalovirus Disease in Kidney Transplant Recipients (MK-8228-002)CompletedPhase 3Merck Sharp & Dohme LLCNCT03443869Written as Acyclovir (ACV)
- Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic LeukemiaCompletedPhase 1/2National Cancer Institute (NCI)NCT00061945Written as acyclovir
- A Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple SclerosisCompletedPhase 1SanofiNCT02977533Written as Acyclovir
- Melatonin Effects on Genital Herpes in Brazilian WomenCompletedPhase 4University of Sao Paulo General HospitalNCT03831165Written as Acyclovir
- Bortezomib in KRAS-Mutant Non-Small Cell Lung Cancer in Never Smokers or Those With KRAS G12DCompletedPhase 2Memorial Sloan Kettering Cancer CenterNCT01833143Written as Acyclovir
- Zinc as Enhancer in Immune Recovery After Stem Cell Transplantation for Hematological MalignanciesCompletedPhase 2Azienda Ospedaliero, Universitaria PisanaNCT03159845Written as Acyclovir 400 MG
- Phase 2 Trial of Carfilzomib for Metastatic Castration-resistant Prostate Cancer Following TreatmentCompletedPhase 2University of Alabama at BirminghamNCT02047253Written as Acyclovir
- Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in AdultsCompletedPhase 1/2University of Wisconsin, MadisonNCT00078559Written as Acyclovir
- Management Of The Infusion-Associated Reactions In RRMS Patients Treated With LEMTRADACompletedPhase 4Genzyme, a Sanofi CompanyNCT02205489Written as aciclovir
- A First-in-human, Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple SclerosisCompletedPhase 1Genzyme, a Sanofi CompanyNCT02282826Written as acyclovir
As the comparator · 8 — what is tested is compared with Acyclovir
- Trial on Efficacy and Safety of Pritelivir Ointment for Treatment of Labial HerpesCompletedPhase 2AiCuris Anti-infective Cures AGNCT02871492Written as Zovirax® cream
- Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes ZosterCompletedPhase 4CttqNCT02151240Written as Acyclovir
- Efficacy of Oral Famciclovir 125mg Comparing to Aciclovir 200 mg Treatment in Patients With Active Recurrent Genital HerpesCompletedPhase 3EMSNCT01281007Written as Aciclovir
- Safety, Tolerability and Therapeutic Efficacy of Topical ZEP-3 Ointment (1.0%) for the Treatment of Cold SoresCompletedPhase 2Shulov Innovate for Science Ltd. 2012NCT02483182Written as Acyclovir cream 5%
- Efficacy of Oral Famciclovir Versus Aciclovir Treatment in Patients With Herpes ZosterCompletedPhase 3EMSNCT01327144Written as Aciclovir
- Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIVCompletedPhase 4University of WashingtonNCT00527618Written as acyclovir
- Valganciclovir in Prevention of Cytomegalovirus (CMV) Reactivation Following Allogeneic-Stem Cell Transplantation (SCT)CompletedPhase 3Hadassah Medical OrganizationNCT00330018Written as Acyclovir
- Non-inferiority Comparison of Efficacy and Safety of Penciclovir 10mg/g to Acyclovir 50mg/g in the Treatment of Recurrent Herpes LabialisCompletedPhase 3EMSNCT01257074Written as Acyclovir 50mg/g
Codes
What other systems call Acyclovir · ClinicalTrials.gg INT006901
- MeSH (NLM) D000212AcyclovirConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) X4HES1O11FACYCLOVIRConfirmed FDA, NLM
- RxNorm 281One source FDA
- NCI Thesaurus C205AcyclovirOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000212 | Acyclovir | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | X4HES1O11F | ACYCLOVIR | Confirmed FDA, NLM |
| RxNorm | 281 | — | One source FDA |
| NCI Thesaurus | C205 | Acyclovir | One source FDA |
Also registered as acyclovir sodium (UNII 927L42J563 · RxNorm 81944).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.