Herpes Simplex clinical trials
The registry lists 306 studies for Herpes Simplex across more than 10 countries. 31 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-22.
Status
- Completed
- 213
- Status unknown
- 30
- Recruiting
- 19
- Terminated
- 17
- Not yet recruiting
- 10
- Withdrawn
- 8
Phase
- Phase 3
- 76
- Phase 2
- 67
- Phase 1
- 47
- Phase 4
- 30
- Early Phase 1
- 1
Where
- United States
- 144
- Canada
- 36
- China
- 26
- Germany
- 22
- United Kingdom
- 19
- Australia
- 17
Who runs them
GlaxoSmithKline (48) · National Institute of Allergy and Infectious Diseases (NIAID) (21) · University of Washington (9) · Novartis (6) · Genocea Biosciences, Inc. (6) · Merck Sharp & Dohme LLC (4) · Radboud University Medical Center (4) · NanoBio Corporation (4)
Studies
Recruiting first, then most recently updated. Showing 50 of 306 — search for more.
- Natural History Study of GATA2 Deficiency and Related DisordersRecruitingNCT019058261 country
- The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known ImmunocompromiseRecruitingNCT010117121 country
- Randomized, Placebo-controlled, Double-blind Study of 2LHERP® in Orofacial Herpes Infections.RecruitingNCT04065971Phase 41 country
- Prevention of Recurrence of Herpes Simplex in Autoimmune Rheumatic DiseasesRecruitingNCT07341386Phase 41 country
- Genetic Studies of Chronic Active Epstein-Barr DiseaseRecruitingNCT000325131 country
- Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BALRecruitingNCT06134492Phase 31 country
- A Phase I Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell)Enrolling by invitationNCT07633197Phase 11 country
- Evaluating Benzoyl Peroxide for Preventing Recurrence of HSV-1 Outbreaks With Rescue Crossover OptionNot yet recruitingNCT07032649Phase 21 country
- Quantification & Classification of Inflammatory Cells in Uveitis Using OCTRecruitingNCT070657471 country
- Pharmacokinetics of Intravenous Acyclovir in Oncologic Paediatric PatientsRecruitingNCT051985701 country
- A Phase Ⅱa Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal KeratitisRecruitingNCT06474442Phase 21 country
- Clinical Study on the Treatment of Herpes Zoster Pain With Dexmedetomidine Combined With Long-term High VoltageRecruitingNCT06978192Phase 21 country
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase IV Clinical Trial to Evaluate the Immunogenicity and Safety of a Live Attenuated Herpes Zoster Vaccine in Adults Aged 40 Years and OlderNot yet recruitingNCT06961721Phase 4
- High-Voltage Long-Duration Pulsed Radiofrequency Combined With Liposomal Bupivacaine Subcutaneous Block for Herpes Zoster-Associated NeuralgiaRecruitingNCT06959147Phase 41 country
- The Efficacy of High-frequency Short-time Spinal Cord Stimulation in the Treatment of Herpes Zoster-associated NeuralgiaRecruitingNCT069428061 country
- Herpes Simplex Virus Type 1 Infection/Reactivation of Patients With Severe Pneumonia（the HSV-SP Study）Not yet recruitingNCT06936683
- Esketamine Combined With PRF of DRG for Acute/Subacute Zoster-associated PainNot yet recruitingNCT06914206Not applicable1 country
- Neuropathic Pain and Traditional Medicine Syndromes in Herpes Zoster: a Cross-Sectional StudyNot yet recruitingNCT068708771 country
- Expanded Access Intermediate Size Treatment Protocol: Pritelivir for Immunocompromised Subjects with Treatment Resistant Herpes Simplex Virus Type 1 or 2AvailableNCT05844436
- A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Recombinant Herpes Zoster VaccineNot yet recruitingNCT06801509Phase 1/21 country
- Multimodal Nerve Block and Pulse Radiofrequency for Acute Herpes Zoster PainNot yet recruitingNCT06798662Not applicable1 country
- Phase III Clinical Trial of Lot-to-lot Consistency of Recombinant Herpes Zoster Vaccine (CHO Cell).Not yet recruitingNCT06654700Phase 31 country
- Impact on Quality of Life and Burden of Disease in Adults With Herpes ZosterNot yet recruitingNCT066672451 country
- Herpes Simplex Meningo Encephalitis RecurrenceRecruitingNCT066270101 country
- Ultrasound Guided Serratus Anterior Versus Erector Spinae Block in Pain Alleviation in Acute Herpes ZosterNot yet recruitingNCT06476080Not applicable
- Treating Genital Herpes Infection to Reduce Racial Disparities in the Risk of Severe Maternal MorbidityRecruitingNCT054293461 country
- Hand Sanitizer Use for Herpes Simplex Virus-1RecruitingNCT06135844Early Phase 11 country
- Herpes Zoster Hospitalizations in ItalyRecruitingNCT059522711 country
- A Phase Ⅲ Clinical Study to Evaluate Protective Efficacy and Safety of a Recombinant Herpes Zoster VaccineRecruitingNCT06088745Phase 31 country
- Epidural Platelet Rich Plasma Injection for Herpes ZosterRecruitingNCT055383641 country
- Bronchoscopic Score for Prediction of Herpes Simplex-virus Type 1 (HSV-1) ReactivationRecruitingNCT053314171 country
- A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.Active, not recruitingNCT05683457Phase 21 country
- Neonatal Phase 1 Valacyclovir StudyCompletedNCT05468619Phase 11 country
- Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised SubjectsCompletedNCT03073967Phase 315 countries
- Trial Evaluating the Immunogenicity and Safety of an Adjuvanted Epstein-Barr Virus (EBV) Glycoprotein 350 Vaccine in EBV-seronegative PersonsCompletedNCT05683834Phase 1/21 country
- Using Artificial Intelligence to Help Doctors Identify Different Skin Conditions and Improve Patient CareCompletedNCT074289541 country
- HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade GliomaWithdrawnNCT04482933Phase 21 country
- A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital HerpesCompletedNCT05298254Phase 1/28 countries
- Clinical Trial to Evaluate EuHZV in Healthy Adults Aged 50 to 69 YearsActive, not recruitingNCT06409494Phase 11 country
- A Study on the Reactogenicity, Safety and Immune Response of a Targeted Immunotherapy Against HSV in Healthy Japanese Participants Aged 18-40 YearsCompletedNCT05989672Phase 11 country
- Efficacy and Safety of Fire Needle Therapy Combined With Cortex Phellodendri Compound Fluid Wet Compress for Acute Herpes Zoster: a Randomized Controlled Trial.CompletedNCT06985589Phase 41 country
- A Study of the Safety, Tolerability and Prelinminary Efficacy of BD111 in Herpes Simplex Virus Type I Stromal KeratitisActive, not recruitingNCT06474416Phase 11 country
- A Study on the Immune Response and Safety of a Vaccine Against Herpes Zoster in Adults Aged 50 Years and Older in IndiaCompletedNCT05219253Phase 31 country
- Ultrasound-Guided Erectro Spinae Plane Block Versus Stellate Ganglion Block for Patients With Upper Limb Acute Herpes Zoster Pain.CompletedNCT06307444Not applicable1 country
- Immunogenicity of Herpes Zoster Subunit Vaccine in Inflammatory Bowel Disease Patients Treated With VedolizumabCompletedNCT03798691Phase 41 country
- Zoster Eye Disease StudyCompletedNCT03134196Phase 42 countries
- An Epidemiological Study to Assess Performance of Using Healthcare Tools to Understand Genital Herpes Simplex Virus-2 (HSV-2) in Patients ≥ 18 Years of Age in the United States and Europe.CompletedNCT049507126 countries
- Rhomboid Intercostal and Subserratus Plane Block Versus Paravertebral Block for Thoracic Herpes ZosterCompletedNCT06751680Not applicable1 country
- Safety and Immunogenicity of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 18 Years and AboveActive, not recruitingNCT05636436Phase 11 country
- Immunogenicity and Safety of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 30 Years and AboveActive, not recruitingNCT05856084Phase 21 country