Sexually Transmitted Diseases clinical trials
The registry lists 523 studies for Sexually Transmitted Diseases across more than 10 countries. 77 are recruiting or about to start. 234 of them are mainly about Sexually Transmitted Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 18 narrower conditions too, such as HIV Infections: 8,213 studies, 801 open.
ClinicalTrials.gov finds 7,927 studies for Sexually Transmitted Diseases. How that becomes 522 here
This page counts the studies the registry files under Sexually Transmitted Diseases, and those it files under no condition that list Sexually Transmitted Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 7,927Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −7,353Filed under a narrower condition, counted on its own pageHIV Infections 4,545 · Acquired Immunodeficiency Syndrome 1,831 · Papillomavirus Infections 511 · HIV Seropositivity 123 · Gonorrhea 89 · Condylomata Acuminata 75 · 7 more
- −12List Sexually Transmitted Diseases as a condition, but the registry did not file them under itMost often written as “Sexually Transmitted Diseases, Bacterial” (6), “Prevention of Sexually Transmitted Infections” (3), and “STD” (1). The registry filed 6 of them under no condition at all, and the others under other conditions only, most often Sexually Transmitted Diseases, Bacterial (6).
- −40Match it another way18 name it in the title, 1 in a keyword, and 21 by a synonym or other text the search reads.
- 522The count on this page
Get an email when these change. Save the Sexually Transmitted Diseases studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Emory University (19) · University of Washington (17) · National Institute of Allergy and Infectious Diseases (NIAID) (17) · Centers for Disease Control and Prevention (16) · University of California, San Francisco (13) · University of Pennsylvania (13) · University of North Carolina, Chapel Hill (12) · RTI International (10)
What is being tested here
Drugs under test in Sexually Transmitted Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Reverse transcriptase inhibitors 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Aug 2027STI Testing to Enhance PrEP Use in Pregnancy · Phase 3 · Botswana Harvard AIDS Institute Partnership
- Nov 2026HIV/STD Risk and PrEP Implementation Messaging Among Gay, Bisexual, and Other Men Who Have Sex With Men · Emory University
- Dec 2026This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests. · American Laboratory Products Company
- Dec 2026Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults · Centre for Infectious Disease Research in Zambia
- Dec 2026Pre-implementation Study to Develop Trans-tailored Services for Transgender Persons in Relation to chemsEX · Institute of HIV Research and Innovation Foundation, Thailand
- Dec 2026Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCT · Hospices Civils de Lyon
- Dec 2026Evaluation of the Q-Pad hrHPV Test System for Identifying Precancer · Qurasense
- Dec 2026Point of Care STI Testing · Icahn School of Medicine at Mount Sinai
- Dec 2026Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic Trial · Children's National Research Institute
- Dec 2026Doxycycline Intervention for Bacterial STI ChemoprOphylaxis (DISCO) · Jonathan Troy Grennan
Who these studies take
Of the 47 Sexually Transmitted Diseases studies recruiting now, 29 (62%) set no upper age limit and 16 (34%) stop at 75 or younger. 22 (47%) take children under 18. 13 (28%) are for women only and 13 (28%) for men only; 33 (70%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (6%) | 0 (0%) |
| 18 | 32 (68%) | 33 (70%) |
| 30 | 25 (53%) | 27 (57%) |
| 40 | 23 (49%) | 26 (55%) |
| 50 | 22 (47%) | 26 (55%) |
| 65 | 21 (45%) | 24 (51%) |
| 75 | 21 (45%) | 24 (51%) |
| 85 | 21 (45%) | 24 (51%) |
Across all 523 studies, recruiting or not: 50% stop at 75 or younger and 48% at 65; 41% take children; 31% are for women only and 21% for men only; 71% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Sexually Transmitted Diseases studies take
Of 14 phase 4 interventional studies under Sexually Transmitted Diseases, half reached primary completion within 32 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 4 | 32 mo15–42 · 14 studies | — | — |
| Interventional, no phase | 31 mo16–46 · 182 studies | — | 32 mo17–47 · 172 studies |
| Observational | 26 mo15–49 · 47 studies | — | 33 mo15–57 · 42 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Results posted2
- Improving HIV Prevention Among Heterosexual Men Seeking STI Services in MalawiNov 12, 2026NCT06200545
- The OPENS Trial: Offering Women PrEP (Aim 2)Nov 4, 2026NCT05619497
Newly registered4
- Daily, Weekly, or Event-driven Doxycycline for STI Prevention Among Men Who Have Sex With Men (MSM) Engaging in Chemsex: The DOSE Non-inferiority TrialNov 9, 2026NCT07925255
- Gamified Interactive Narrative (REPRO-QUEST) on Sexual Health Literacy and Sexually Transmitted Infection Prevention BehaviorsOct 21, 2026NCT07886073
- A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African WomenOct 20, 2026NCT07884240
- Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCTOct 20, 2026NCT07884656
Studies
Recruiting first, then most recently updated. Showing 50 of 523. Browse all 523 → or search them.
- Daily, Weekly, or Event-driven Doxycycline for STI Prevention Among Men Who Have Sex With Men (MSM) Engaging in Chemsex: The DOSE Non-inferiority TrialNot yet recruitingNCT07925255Phase 41 country
- HIV/STI/HCV Testing and Overdose Prevention Among Survivors of Sex TraffickingNot yet recruitingNCT07264582Not applicable1 country
- PNF RCT to Decrease Alcohol Use and Increase HIV PreventionNot yet recruitingNCT07731932Not applicable1 country
- Pilot HIV Self-Testing And Self-collected STI Testing Strategy for Sex Worker Empowerment StudyNot yet recruitingNCT07829133Not applicable1 country
- Using Mobile Health (mHealth) to Improve STI Treatment Adherence Among AdolescentsRecruitingNCT04372485Not applicable1 country
- A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African WomenNot yet recruitingNCT07884240Phase 34 countries
- Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCTNot yet recruitingNCT07884656Not applicable1 country
- Doxycycline Prophylaxis for Prevention of Sexually Transmitted InfectionsRecruitingNCT06738407Phase 41 country
- Combatting HIV Or Other STIs Early (CHOOSE)RecruitingNCT07510048Not applicable1 country
- Assessing the Effects of a Multisectoral Agricultural Intervention on the Reproductive and Sexual Health of Adolescent Girls and Young WomenRecruitingNCT06953310Not applicable1 country
- Outcomes From Point-of-Care Sexually Transmitted Infection (STI) Testing in an Urban Sexual Health Clinic: A Randomized TrialNot yet recruitingNCT07399873Not applicable
- Sexual Behavior and Risk Perception as Factors Associated With STI Incidence in Young AdultsRecruitingNCT078462411 country
- Prospective Registry of Exposure to Gepotidacin (PREG)Not yet recruitingNCT07850141
- Prison-Based HIV Partner NotificationRecruitingNCT07103928Not applicable1 country
- The Integrated Female Sexually Transmitted Infection Testing for HIV Epidemic Control Through PrEP (IN-STEP) StudyRecruitingNCT06743204Not applicable1 country
- Characterization of Doxycycline Pharmacokinetics and AdherenceEnrolling by invitationNCT07755618Phase 11 country
- This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.RecruitingNCT070898361 country
- Improving Maternal and Child Health Through Point-of-care STI TestingRecruitingNCT07290439Not applicable1 country
- Community Popular Opinion Leader Intervention for HIV Prevention Uptake in Rural South AfricaNot yet recruitingNCT07741474Not applicable1 country
- Evaluation of the Q-Pad hrHPV Test System for Identifying PrecancerRecruitingNCT07281599Not applicable1 country
- 500-mg Versus 1000-mg Ceftriaxone for Uncomplicated Gonorrhea InfectionRecruitingNCT07710118Phase 31 country
- Developing an HIV Disclosure Intervention for Men in UgandaNot yet recruitingNCT05771519Not applicable1 country
- Health-E You Efficacy Trial for Male AdolescentsRecruitingNCT06525064Not applicable1 country
- #TranscendentHealth: A Text Messaging Pregnancy Prevention Program for Transgender BoysNot yet recruitingNCT07681908Not applicable1 country
- Healthy Expectancy Through Routine Antenatal STI ScreeningRecruitingNCT07458802Not applicable1 country
- Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated StrategyNot yet recruitingNCT07658976Phase 34 countries
- Efficacy of Temocillin Compared to Standard of Care in the Treatment of Neisseria Gonorrhoeae InfectionsNot yet recruitingNCT07631364Phase 31 country
- Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive YearsRecruitingNCT05910580Not applicable1 country
- STI Testing to Enhance PrEP Use in PregnancyRecruitingNCT06919614Phase 31 country
- Effects of Copper Versus Levonorgestrel Intrauterine Devices on Mucosal Microbiota and Barrier Function Among Young African WomenNot yet recruitingNCT07627958Not applicable1 country
- Protocol RV 583 Multinational Observational Cohort of HIV and Other InfectionsRecruitingNCT051475194 countries
- Gathering Online for Dialogue and Discussion to Enhance Social SupportRecruitingNCT05753683Not applicable1 country
- Point of Care STI TestingRecruitingNCT06844045Not applicable1 country
- "Sexual Health Assessment of TinidaZole Against M. Genitalium (SHAZAM)"RecruitingNCT07088419Phase 21 country
- Epidemiology of Sexually Transmitted Infections and Its iMpAcT on fEmale InfertilityRecruitingNCT052449671 country
- Got Doxy- 'Flipping the Script' on STI PEPRecruitingNCT07215325Phase 41 country
- Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in VeteransNot yet recruitingNCT06766331Not applicable1 country
- IMARA for Black Male Caregivers and Girls Empowerment (IMAGE)RecruitingNCT06266416Not applicable1 country
- Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency DepartmentNot yet recruitingNCT07525076Not applicable1 country
- Impact of Internal Menstrual Protections on Immunity and Vaginal MicrobiotaRecruitingNCT071999981 country
- Integrating Sexual Pleasure Into Harm Reduction Services for Men Who Have Sex With Men and Transgender Persons Who Engage in Chemsex or Substance Use in ThailandRecruitingNCT07509853Not applicable1 country
- Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, SwitzerlandNot yet recruitingNCT07516912
- Next4You: A Fully Mobile Relationships Based Program for Youth in Foster CareEnrolling by invitationNCT06127277Not applicable1 country
- Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation StudyRecruitingNCT075128691 country
- The Implementation of a Trans-tailored Harm Reduction Service for Transgender Persons in Relation to chemsEX and Substance Use (iT-REX)RecruitingNCT07512856Not applicable1 country
- Pre-implementation Study to Develop Trans-tailored Services for Transgender Persons in Relation to chemsEXRecruitingNCT075058751 country
- California MEPS HubRecruitingNCT07433985Not applicable1 country
- Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de JaneiroRecruitingNCT07500415Not applicable1 country
- Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic TrialRecruitingNCT04372875Not applicable1 country
- Integrated Health Services (IHS): A Structural Intervention to Improve HIV/STI Screening and PrEP Navigation in Primary CareNot yet recruitingNCT07446764Not applicable1 country