Varicose Veins clinical trials
The registry lists 226 studies for Varicose Veins across more than 10 countries. 30 are recruiting or about to start. 165 of them are mainly about Varicose Veins (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Varicose Ulcer too: 580 studies, 106 open.
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Who runs them
Boston Scientific Corporation (11) · Imperial College London (10) · Pirogov Russian National Research Medical University (10) · Singapore General Hospital (6) · Hull University Teaching Hospitals NHS Trust (6) · Belarusian State Medical University (5) · Chengdu University of Traditional Chinese Medicine (5) · Korea University (4)
What is being tested here
Drugs under test in Varicose Veins studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026HEMOVAR Study on Hemorrhoids and Varicose Veins · Aydin Adnan Menderes University
- Dec 2026Comparison of Radiofrequency Ablation With Concomitant or Staged Treatment for Tributary Varicose Veins · Sir Run Run Shaw Hospital
- Dec 2026Pilot Study: Evaluation of the Safety of the Application of Non-thermal HIFU for Varicose Veins Treatment of the Lower Limbs · VeinSound
- Dec 2026Subfascial Endoscopic Perforator Surgery (SEPS) Versus Open Ligation for Lower Limb Varicose Veins · King Edward Medical University
- Jan 2027Elastic Compression Stockings and Varicose Veins Recurrence · Pirogov Russian National Research Medical University
- Jan 2027Caprini Score in Venous Surgery: a Prospective Cohort Study · Pirogov Russian National Research Medical University
- Jan 2027Pain During Heat Treatment for Lower Extremity Varicose Veins: Radiofrequency vs. Microwave · Chunshui He
- Jun 2027Trial to Evaluate Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Venous Leg Ulcers · AOTI Ltd.
- Jun 2027THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE) · Imperial College London
- Aug 2027Mechanochemical Ablation Versus Ultrasound-Guided Foam Sclerotherapy of the Great Saphenous Vein · Antonio Eduardo Zerati
Who these studies take
Of the 22 Varicose Veins studies recruiting now, 12 (55%) set no upper age limit and 4 (18%) stop at 75 or younger. 2 (9%) take children under 18. 1 (5%) are for women only and 0 (0%) for men only; 2 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (5%) | 1 (5%) |
| 18 | 20 (91%) | 19 (86%) |
| 30 | 21 (95%) | 20 (91%) |
| 40 | 22 (100%) | 21 (95%) |
| 50 | 21 (95%) | 21 (95%) |
| 65 | 21 (95%) | 21 (95%) |
| 75 | 20 (91%) | 20 (91%) |
| 85 | 14 (64%) | 14 (64%) |
Across all 226 studies, recruiting or not: 25% stop at 75 or younger and 9% at 65; 6% take children; 7% are for women only and 1% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Varicose Veins studies take
Of 72 interventional studies with no phase under Varicose Veins, half reached primary completion within 22 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 22 mo11–48 · 72 studies | — | 25 mo12–48 · 62 studies |
| Observational | 29 mo19–96 · 30 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 226. Browse all 226 → or search them.
- Natural History of Noncirrhotic Portal HypertensionRecruitingNCT024177401 country
- Phenotyping Rehabilitation for Improving Frailty, Functional CapacityNot yet recruitingNCT07907978Not applicable
- Pilot Study: Evaluation of the Safety of the Application of Non-thermal HIFU for Varicose Veins Treatment of the Lower LimbsRecruitingNCT07878767Not applicable1 country
- Subfascial Endoscopic Perforator Surgery (SEPS) Versus Open Ligation for Lower Limb Varicose VeinsRecruitingNCT07872150Not applicable1 country
- Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram TrialNot yet recruitingNCT07168395Not applicable
- Registry for Chronic Venous Disease Incidence and Natural CourseRecruitingNCT044873141 country
- THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)RecruitingNCT05735639Phase 41 country
- Research on the Application of Nursing Intervention Based on ITHBC Theory in Postoperative Self-Management of Patients With Varicose Veins of the Lower ExtremitiesRecruitingNCT07570277Not applicable1 country
- Polidocanol Foam With or Without Transdermal Laser in Varicose VeinsRecruitingNCT07276243Not applicable1 country
- Mechanochemical Ablation Versus Ultrasound-Guided Foam Sclerotherapy of the Great Saphenous VeinRecruitingNCT07561320Phase 41 country
- HEMOVAR Study on Hemorrhoids and Varicose VeinsRecruitingNCT073174921 country
- Study on Treatment of Varicose Veins by Endovenous Laser (1940 nm vs 1470 nm)RecruitingNCT05663359Not applicable1 country
- The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein ProgressionRecruitingNCT07449728Not applicable1 country
- Comparison of Radiofrequency Ablation With Concomitant or Staged Treatment for Tributary Varicose VeinsNot yet recruitingNCT07445425Not applicable1 country
- Caprini Score in Venous Surgery: a Prospective Cohort StudyRecruitingNCT030418051 country
- Study to Find Out the Timing for the Optimal Imaging of Varicose Veins Using Infrared Thermography.RecruitingNCT073340281 country
- Trial to Evaluate Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Venous Leg UlcersRecruitingNCT06754735Phase 41 country
- Effect of Oral Antiplatelet or Anticoagulant Drugs on Postoperative Bleeding Risk and Venous Closure Rate in Patients With Lower Extremity Varicose Veins After Radiofrequency AblationNot yet recruitingNCT07208695
- Vacuum-assisted Laser Ablation (VALA) for Treatment of Large Saphenous VeinsRecruitingNCT06971068Not applicable4 countries
- Study of Venous Outflow From the Lower Limbs in Patients With Pelvic VaricositiesRecruitingNCT061246641 country
- Evaluating QoL and Postoperative Complications Using TEThA Technique in the Treatment of Tributary VeinsNot yet recruitingNCT06669260
- Study of Foam Sclerotherapy Versus Ambulatory PhlebectomyRecruitingNCT03416413Phase 41 country
- Noninvasive Diagnosis Model for High-risk Varices in CirrhosisRecruitingNCT063925031 country
- Comparative Clinical Efficacy Between Multi-layer Bandage Pressure Therapy and Gradient Pressure Elastic Stocking Treatment After Endovenous Radiofrequency AblationRecruitingNCT06366763Not applicable1 country
- Ongoing Registry of Treatment of Chronic Venous DiseasesRecruitingNCT030357471 country
- Daily Duration of Compression Treatment in Patients With Symptomatic Chronic Venous DiseaseEnrolling by invitationNCT06175546Not applicable1 country
- Effect of Cold Immersion on Patients With Varicose VeinNot yet recruitingNCT05930587Not applicable1 country
- Feasibility Study of Ultrasound-guided Functional Remodeling of Lower Extremity Superficial Venous ValveRecruitingNCT05914740Not applicable1 country
- Effect of Short-term Compression Therapy After Thermal Ablation for Varicose VeinsRecruitingNCT05840991Not applicable1 country
- Comparison of Daytime Surgery in Varicose Veins Patients With and Without Superficial Venous ThrombosisNot yet recruitingNCT053808951 country
- Pain During Heat Treatment for Lower Extremity Varicose Veins: Radiofrequency vs. MicrowaveActive, not recruitingNCT079073151 country
- PREservation Versus Thermal AblationActive, not recruitingNCT040343291 country
- Non-Inferiority Clinical Evaluation of a Novel Varicose Vein Closure Adhesive System for Lower Extremity Varicose VeinsCompletedNCT07827339Not applicable1 country
- Prolonged Compression Following Foam SclerotherapyActive, not recruitingNCT06766968Not applicable1 country
- VenaSeal Spectrum: Global Post-Market Randomized Controlled TrialTerminatedNCT03820947Not applicable10 countries
- Allopurinol Versus Atorvastatin to Prevent Complications of Liver CirrhosisCompletedNCT05511766Phase 2/31 country
- Prevalence of Pelvic Venous Congestion Syndrome in Female Patients With Lower Extremity Varicose Veins and Its Impact on Postoperative Quality of Life Improvement Following Radiofrequency Ablation: A Single-Center Prospective Cohort Study(PCSRFStudy)Active, not recruitingNCT076804651 country
- Endovenous Laser Ablation With 1940 nm Versus 1470 nmActive, not recruitingNCT07603570Phase 31 country
- Regional Anesthesia and Recovery After Varicose Vein RFACompletedNCT075140001 country
- Outpatient Office Based Endovascular ProceduresCompletedNCT040544401 country
- Varithena Versus Endothermal Ablation of the Great Saphenous Vein (VERITAS)TerminatedNCT05312970Phase 41 country
- Efficacy of the SALFOAM 3% Method Compared to the Conventional Polidocanol Foam Method (Tessari Method) for Treating Lower Limb Varicose VeinsCompletedNCT06667570Not applicable1 country
- A Study of Soundscapes for Patient WellbeingCompletedNCT05650073Not applicable1 country
- Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose VeinsActive, not recruitingNCT06367166Not applicable1 country
- Varicose Veins in Petrol Pump WorkersCompletedNCT070718051 country
- First- or Second- Class Compression Hosiery After Endovenous Laser With Sclerotherapy and Ambulatory PhlebectomyCompletedNCT06913764Not applicable1 country
- Endovenous Radiofrequency Ablation Closure System in the Treatment of Varicose VeinsCompletedNCT04671641Not applicable1 country
- Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal StudyCompletedNCT05926830Not applicable3 countries
- Elastic Compression Stockings and Varicose Veins RecurrenceActive, not recruitingNCT04231942Not applicable1 country
- Pilot RCT Evaluating a One Stop Vein ClinicTerminatedNCT02557542Not applicable1 country