Varicocele clinical trials
The registry lists 53 studies for Varicocele across more than 10 countries. 15 are recruiting or about to start. 39 of them are mainly about Varicocele (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Who runs them
Assiut University (10) · Mansoura University (3) · Sohag University (3) · Fayoum University Hospital (2) · Benha University (2) · Medical University of Warsaw (2) · Icahn School of Medicine at Mount Sinai (1) · U.O. Chirurgia Andrologica (1)
What is being tested here
Drugs under test in Varicocele studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Lidocaine | 0 | 0 | 1 |
| Levobupivacaine | 0 | 0 | 1 |
| Follitropin beta | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 9, phase 3 first
- Jun 2027Comparative Study of Post-Varicocelectomy Myo-inositol vs. Antioxidants vs. Surgery Alone in Infertile Men · Phase 3 · Fayoum University Hospital
- Nov 2026Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils · Medtronic Endovascular
- Nov 2026Reflux Flow Volume Impact on Semen Parameters Pre and Post Varicocelectomy · Assiut University
- Nov 2026HEMOVAR Study on Hemorrhoids and Varicose Veins · Aydin Adnan Menderes University
- Mar 2027Transjugular and Transfemoral Embolization for Varicocele. · Sohag University
- May 2027Intratesticular Artery Resistive Index Changes After Varicocelectomy · Assiut University
- Jun 2027Microscopic Varicocele Bypass Versus Ligation · Ke Dou
- Aug 2027Effect of Varicocelectomy on Spermatogenic Cell Count and Semen Parameters · Assiut University
- Sep 2027Effects of Visceral Osteopathic Massage on Semen Parameters and Hemodynamics Factors in Varicocele · Ankara Yildirim Beyazıt University
Who these studies take
Of the 4 Varicocele studies recruiting now, 2 (50%) set no upper age limit and 2 (50%) stop at 75 or younger. 1 (25%) take children under 18. 0 (0%) are for women only and 3 (75%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (25%) | 3 (75%) |
| 30 | 1 (25%) | 3 (75%) |
| 40 | 1 (25%) | 4 (100%) |
| 50 | 1 (25%) | 4 (100%) |
| 65 | 1 (25%) | 3 (75%) |
| 75 | 1 (25%) | 3 (75%) |
| 85 | 1 (25%) | 2 (50%) |
Across all 53 studies, recruiting or not: 68% stop at 75 or younger and 62% at 65; 21% take children; 2% are for women only and 79% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 53. Browse all 53 → or search them.
- Comparative Study of Post-Varicocelectomy Myo-inositol vs. Antioxidants vs. Surgery Alone in Infertile MenNot yet recruitingNCT07915388Phase 31 country
- Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable CoilsEnrolling by invitationNCT076398531 country
- Internal Spermatic Vein Histopathology in Patients Undergoing VaricocelectomyNot yet recruitingNCT07836413
- Transjugular and Transfemoral Embolization for Varicocele.RecruitingNCT07764900Not applicable1 country
- Recover@Home Postoperative Follow-up StudyNot yet recruitingNCT07714343Not applicable1 country
- Effect of Varicocelectomy on Spermatogenic Cell Count and Semen ParametersNot yet recruitingNCT07684963Not applicable
- Effects of Visceral Osteopathic Massage on Semen Parameters and Hemodynamics Factors in VaricoceleNot yet recruitingNCT07665905Not applicable1 country
- Selective Extended Venous Stripping Versus Standard Microsurgical Varicocelectomy for Varicocele-Related Male InfertilityNot yet recruitingNCT07605351Not applicable1 country
- HEMOVAR Study on Hemorrhoids and Varicose VeinsRecruitingNCT073174921 country
- Intratesticular Artery Resistive Index Changes After VaricocelectomyNot yet recruitingNCT07517952Not applicable
- Reflux Flow Volume Impact on Semen Parameters Pre and Post VaricocelectomyNot yet recruitingNCT07263009
- Microscopic Varicocele Bypass Versus LigationNot yet recruitingNCT07065695Not applicable1 country
- Vivifi's Treatment, BPH Treatment Via Vasculature AnastomosisRecruitingNCT06424912Not applicable1 country
- Evaluation of Fertitonex Effects on Semen Parameters in Clinical Varicocele Patient.RecruitingNCT06718426Not applicable1 country
- A Prospective Cohort Study of Combined Subinguinal Varicocele Ligation and SclerotherapyNot yet recruitingNCT06743932
- Varicocelectomy for Cryptozoospermic Men.CompletedNCT07759713Not applicable1 country
- Zonulin Levels in Varicocele PatientsCompletedNCT077481041 country
- Comparison of Open Versus Laparoscopic High Ligation Varicocelectomy For The Treatment Of VaricoceleCompletedNCT07353164Not applicable1 country
- Comparison Between Loupe-Assisted Varicocelectomy With Nitroglycerin Instillation and Microscopic VaricocelectomyCompletedNCT06509321Not applicable1 country
- "Comparison of USG-Guided Caudal Versus Ilioinguinal/Iliohypogastric Nerve Block for Pediatric Inguinal Surgeries"Status unknownNCT05558748Not applicable1 country
- Evaluating Patient Tolerability and Success for Penile and Scrotal Urologic Procedures Under Conscious Sedation: A Prospective StudyStatus unknownNCT056172611 country
- Effect of Recent Ejaculation on Scrotal Duplex Parameters in Infertile Males With VaricoceleStatus unknownNCT05330533
- Lactoferrin and Iron in Seminal Plasma of VaricoceleStatus unknownNCT05171504
- The Effect of Subcutaneous and Intraperitoneal Anesthesia on Post Laparoscopic PainCompletedNCT05034406Not applicable1 country
- Assessment of Seminal Levels of Cystatin C and Endoglin in Infertile Men With VaricoceleCompletedNCT04856579Not applicable1 country
- Varicocele Treatement by Endovasculer EmbolizationStatus unknownNCT03341897Not applicable
- EASYX-1 : A Multicenter Study on Safety and Efficacy of Easyx Liquid Embolization Agent Used in Five Separate IndicationsCompletedNCT03477149Not applicable1 country
- "Outcome of Varicocelectomy on Normal Semen in Patients Complaining of OrchialgiaCompletedNCT04509869Not applicable1 country
- Seminal TEX101 as a Predictor of Recovery of Spermatogenesis in Azoospermic Men With Palpable VaricoceleCompletedNCT04397887Not applicable1 country
- Testicular Growth During Puberty in Boys With and Without a Left-sided VaricoceleStatus unknownNCT035400561 country
- The Anaesthesiological Approach to Varicocele Correction in Outpatients Setting: an Observational AnalysisCompletedNCT024010871 country
- The Search for Viral and Bacterial Etiology of VaricoceleStatus unknownNCT03079609Not applicable1 country
- The Role of Microsurgery in Surgical Treatment of Varicocele.Status unknownNCT02722187Not applicable1 country
- Effect of TAP Block for Postoperative Pain Control After Varicocele Operations.CompletedNCT02983383Not applicable1 country
- Analysis on AEFI Surveillance Data for Live Attenuated Varicella VaccineCompletedNCT02983656
- Quality of Life Among Testicular Cancer SurvivorsStatus unknownNCT023045751 country
- the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen AnalysisStatus unknownNCT032819151 country
- IVF Outcomes After Varicocele RepairStatus unknownNCT03090438Not applicable
- Role of FSHR Polymorphism p.N680S in the Therapy With FSH in Patients Who Underwent Varicocele SurgeryStatus unknownNCT02719093Phase 4
- Doppler Ultrasound Assisted Varicocelectomy Improve Sperm QualitiesStatus unknownNCT02695199Not applicable1 country
- Assessing the Rates of Major Complications in Combined Mini-incision Microscopic VaricocelectomyCompletedNCT02092311Not applicable1 country
- Evaluation of PerformanCe of the Peripheral EOS in the Treatment of Varicocele or Pelvic Congestion SynDromEStatus unknownNCT020338633 countries
- Single Incision Laparoscopic VaricocelectomyCompletedNCT02335385Not applicable
- Outcome of ICSI Using Cryopreserved Testicular Sperm From Infertile Men With Varicocele-associated AzoospermiaStatus unknownNCT02306499Not applicable1 country
- Beneficial Effects of Microsurgical Varicocelectomy on Semen Parameters for Causes Other Than InfertilityCompletedNCT020063161 country
- Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?TerminatedNCT01296230Not applicable1 country
- Comparison of Outcomes of Two Approaches in Microsurgical Varicocelectomy in Chinese Infertile Males: A Prospective Randomized, Controlled TrialCompletedNCT01463787Phase 41 country
- The Effect and Prognosis of Different Operations on Varicocele - a Single-center Clinical StudyStatus unknownNCT01757548Not applicable1 country
- Canadian Varicocelectomy Initiative (CVI): Effects on Male Fertility and Testicular Function of VaricocelectomyTerminatedNCT00961558Not applicable1 country
- Varicocelectomy To Treat Pain, Predictors Of SuccessCompletedNCT01395186Not applicable1 country