An interventional study of Varicocelectomy in Varicocele and Infertility, Male, sponsored by Benha University. Completed at 2 sites in Egypt. Open to male participants aged 18 Years to 39 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-04-23.
Sponsored by Benha University · Not applicable, Interventional, and Basic science
Varicocele is a major contributor in male infertility. The improvement of sperm parameters after varicocelectomy supports this contribution. The pathophysiological mechanisms of varicocele-induced male infertility are still under investigation. Cystatin C (Cys C) and endoglin are secreted glycoproteins that recently linked to several cellular changes common in varicocele like apoptosis and autophagy.
Subinguinal varicocelectomy under general anesthesia and complete aseptic condition was done to infertile men with varicocele
53 studies on the registry are indexed under Varicocele; 15 are open to participants now.
This study's enrollment of 30 is below the median of 72 across 36 interventional studies indexed under Varicocele.
Browse Varicocele studies →Benha University is the lead sponsor of 362 studies on the registry; 66 are open to participants now.
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Exclusion Criteria:
Subinguinal varicocelectomy under general anesthesia and complete aseptic condition
Procedure: Varicocelectomy
Subinguinal varicocelectomy under general anesthesia and complete aseptic condition
The Quality of Semen
According to WHO 2010 guidelines regarding semen analysis * Sperm concentration (to be more than 15 million sperm per milliliter). * Sperm motility (not less than 60% progressive motility). * Sperm morphology (not less than 6% normal morphology).
Time frame: 6 months
Plan to share: Undecided
No publications or documents are linked to this record.
Ran from Jan 2019 to primary completion in Dec 2020, 23 months.
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This study is completed, as verified in Apr 2021. You cannot join it, but the record below documents what was studied.
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