ClinicalTrials.gg
RecruitingNCT03765333Updated Sep 22, 2026

GETNE Registration of Thyroid Cancer

An observational study in Thyroid Cancer, sponsored by Grupo Espanol de Tumores Neuroendocrinos. Recruiting at 1 site in Spain. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-22.

Sponsored by Grupo Espanol de Tumores Neuroendocrinos · Observational

From the registry’s dates

  • Started May 2019; still recruiting 7 years 5 months later.
Study type
Observational
Model
Ecologic or community
Time perspective
Cross-sectional
Enrollment
20
Ages
18 Years and older
Sex
All
01

Study summary

An epidemiological, observational, multicenter, cross-sectional, retrospective study on patients ≥ 18 years visited in the oncology services of the participating centers with diagnosis of primary thyroid cancer.

02

Conditions studied

  • Thyroid Cancer

Browse trials for

03

In context

Thyroid Neoplasms

785 studies on the registry are indexed under Thyroid Neoplasms; 204 are open to participants now.

This study's planned enrollment of 20 is below the median of 178 across 241 observational studies indexed under Thyroid Neoplasms.

Browse Thyroid Neoplasms studies →

Lead sponsor

Grupo Espanol de Tumores Neuroendocrinos is the lead sponsor of 21 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients ≥ 18 years visited in the oncology services of the participating centers that have a diagnosis of primary cancer located in the thyroid gland.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients older than 18 years with diagnosis of differentiated, medullary or anaplastic thyroid cancer confirmed by histopathology.
  • Patients who agree to participate and are able to understand the information sheet and sign the

Exclusion criteria

Exclusion Criteria:

  • Patients under 18 years of age.
  • Patients with other types of thyroid cancer or whose histopathological diagnosis has not been confirmed.
  • Patients who do not have the relevant basic information to be included in the study, according to the criteria of the principal investigator.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Ecologic or community
Time perspective
Cross-sectional
Enrollment
20 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Hystopathological characteristics of the tumor

    Based on pathologist evaluation of biopsy including differentiated, medullar or anaplasic.

    Time frame: Baseline

  2. Situation of the tumor at first-diagnosis

    Local tumor, locoregional tumor or metastatic disease.

    Time frame: Baseline

  3. Tumor-Node-Metastasis classification

    Based on the AJCC (American Joint Committee on Cancer) 2018 TNM system: T for extent or size of the tumor, N for lymph nodes spread and M for metastasis.

    Time frame: Baseline

  4. Tumor Stage

    From I to IV, based on the interpretation of the TNM classification and depending on the hystopathological characteristics of the tumor.

    Time frame: Baseline

Secondary outcomes

  1. Patient situation at the end of treatment

    Results of clinical evaluation of the disease including complete response, partial response, stable disease, progression of disease or death

    Time frame: 12 months

  2. Number of patients with BRAF mutation

    Total patients with available results on BRAF status and proportion of patients with mutated BRAF or native BRAF.

    Time frame: 12 months

  3. Number of patients with RET mutation

    Total patients with available results on RET status and proportion of patients with mutated RET or native RET.

    Time frame: 12 months

  4. Number of patients with PI3K mutation

    Total patients with available results on PI3K status and proportion of patients with mutated PI3K or native PI3K.

    Time frame: 12 months

  5. Number of patients with RAS mutation

    Total patients with available results on RAS status and proportion of patients with mutated RAS or native RAS.

    Time frame: 12 months

  6. Number of patients with PAX8/PAR mutation

    Total patients with available results on PAX8/PAR status and proportion of patients with mutated PAX8/PAR or native PAX8/PAR.

    Time frame: 12 months

  7. Number of patients with P53 mutation

    Total patients with available results on P53 status and proportion of patients with mutated P53 or native P53.

    Time frame: 12 months

  8. Number of patients with PTEN mutation

    Total patients with available results on PTEN status and proportion of patients with mutated PTEN or native PTEN.

    Time frame: 12 months

07

Study locations

1 of 1 sites recruiting
  • Hospital Universitari Vall d'Hebron
    Barcelona, Barcelona, Spain
    Recruiting
    • A responsible person designated by the sponsor, M.D. · Contactinvestigacion@mfar.net
    • Principal investigator selected by the sponsor, M.D. · Principal investigator
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started May 2019 (actual). Primary completion is estimated for Dec 2028, 115 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 20, 2018
First posted
Dec 5, 2018
StartActual
May 28, 2019
Primary completionEst.
Dec 2028
CompletionEst.
Dec 2028
Last update
Sep 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03765333
Lead sponsor
Grupo Espanol de Tumores Neuroendocrinos
Responsible party
Sponsor
First posted
Dec 5, 2018
Start date
May 28, 2019
Primary completion
Dec 2028 (estimated)
Completion
Dec 2028 (estimated)
Last update
Sep 22, 2026

Study contacts

Secretaria Técnica GETNE
Contact
getne@mfar.net
+34 93 434 44 12
Jorge Hernando Cubero, M.D.
study director · Hospital Universitari Vall d'Hebron, Barcelona
Jaume Capdevila, M.D.
study chair · Hospital Universitari Vall d'Hebron, Barcelona

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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