An interventional study of WeChat-supported Neck Rehabilitation Exercise and Standardized Postoperative Care and Video Education in Thyroid Diseases, Thyroid Cancer and Surgery, sponsored by Shanghai 6th People's Hospital. Recruiting at 1 site in China. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-09-10.
Sponsored by Shanghai 6th People's Hospital · Not applicable, Interventional, and Supportive care
Among 160 studies in Thyroid Neoplasms with a site in China — 65 open to participants now, 72 under way, 6 of them phase 3. Thyroid Neoplasms · China.
Among the 160 studies in Thyroid Neoplasms with a site in China, this one is the 33rd largest by planned enrollment of the 108 interventional ones, is one of 11 that started in 2026, is one of 41 with no phase, reaches primary completion later than 58 of the 71 other live ones, and was the 153rd registered.
785 studies on the registry are indexed under Thyroid Neoplasms; 204 are open to participants now.
This study's planned enrollment of 200 is above the median of 53 across 520 interventional studies indexed under Thyroid Neoplasms.
Browse Thyroid Neoplasms studies →65 of the 160 studies in Thyroid Neoplasms with a site in China are open now, in 12 countries. Each count lists the studies.
Of the 152 Thyroid Neoplasms studies recruiting now, 96 (63%) set no upper age limit and 27 (18%) stop at 75 or younger; 37 take children under 18; 13 take healthy volunteers.
This study: 18 Years to 60 Years · all sexes · no healthy volunteers.
The full table on the hub →160 studies; the count open now beside each. This study's row is marked.
First in 2006; this study’s year is marked. 11 started in 2026.
Median enrollment 106 across the 108 interventional studies, 300 across the 52 observational. Of the 47 that completed or were terminated, 6 (13%) have results posted.
29 of 160 have an industry lead sponsor. The 10 most frequent:
Shanghai 6th People's Hospital is the lead sponsor of 70 studies on the registry; 41 are open to participants now.
Shanghai 6th People's Hospital has 4 studies filed under Thyroid Neoplasms — fewer than ten, so there is no comparison to draw.
17 of the studies in Thyroid Neoplasms with a site in China that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06860971Phase 3Chia Tai Tianqing Pharmaceutical Group Co., Ltd.A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma | 2027-01 |
| NCT07459283FindCure Biosciences (ZhongShan) Co., Ltd.The Safety, Dosimetry and Efficacy of 177Lu-INN805 in Patients With Malignant Solid Tumors | 2026-12 |
| NCT06623500Shandong Provincial HospitalIodine Nutrition Status and Clinical Characteristics of Thyroid Cancer | 2026-12-01 |
| NCT07359586Zhejiang UniversityLaryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia | 2026-12-25 |
| NCT06970353Fudan UniversityPhase II Trial of Tunlametinib in NRAS-Mutant Advanced Thyroid Cancer | 2026-12-30 |
Among the 160 studies in Thyroid Neoplasms with a site in China, from their registry updates:
This study aimed to evaluate the effectiveness, safety, and implementation outcomes of a WeChat mini program-supported tele-neck rehabilitation exercises for improving early postoperative neck recovery after thyroidectomy.
785 studies on the registry are indexed under Thyroid Neoplasms; 204 are open to participants now.
This study's planned enrollment of 200 is above the median of 53 across 520 interventional studies indexed under Thyroid Neoplasms.
Browse Thyroid Neoplasms studies →Shanghai 6th People's Hospital is the lead sponsor of 70 studies on the registry; 41 are open to participants now.
Compared within Thyroid Neoplasms, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Thyroid Diseases. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants in the WeChat-supported tele-rehabilitation group received WeChat mini program-supported postoperative neck exercise management.
Behavioral: WeChat-supported Neck Rehabilitation Exercise · Behavioral: Standardized Postoperative Care and Video Education
Participants in the routine care group did not receive WeChat mini program-supported postoperative neck exercise management.
Behavioral: Standardized Postoperative Care and Video Education
WeChat mini program-supported neck exercise management includes daily exercise reminders, exercise check-ins, symptom reporting, automated abnormal symptom prompts, and standardized remote feedback from the research team.
This intervention consists of standard clinical postoperative care and discharge education, encompassing wound management, follow-up appointments, and generic neck activity guidelines. Prior to discharge or upon clinical stability, participants undergo a one-time, face-to-face training session with research staff featuring practical exercise demonstrations and behavioral precautions, and are provided with identical instructional video materials for home reference.
Neck Pain and Disability Scale (NPDS) Score
The NPDS is used to evaluate post-surgical neck pain and its multi-dimensional impact on daily living, emotions, work, and social activities. The total score ranges from 0 to 100, with higher scores representing more severe neck pain and structural functional impairment.
Time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Neck Movement Pain Score
Assessment of localized pain severity provoked during active cervical movements, including neck flexion, extension, left/right lateral flexion, and left/right rotation. Each of the six movements is scored categorically as 0 (painless), 1 (mild pain), or 2 (severe pain), yielding a cumulative score range of 0 to 12. Higher total scores indicate more pronounced motion-induced cervical pain.
Time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Health-related quality of life
Health-related quality of life will be assessed using the EuroQol 5-Dimension 5-Level questionnaire (EQ-5D-5L). The descriptive system assesses five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, with five response levels for each dimension.
Time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Incidence of Surgical Complications and Intervention-Related Adverse Events
Safety endpoints mapping the frequency and severity of post-surgical complications (e.g., wound bleeding/hematoma, incision dehiscence, surgical site infection) or any adverse events deemed by the investigator to be potentially related to the physical exercise regimen (e.g., severe motion-induced pain exacerbation, acute dizziness).
Time frame: Up to 3 month post-operation
Cervical Range of Motion (ROM)
Objective clinical measurement of neck mobility, quantifying the exact degrees of cervical movement achieved during forward flexion, backward extension, left/right lateral flexion, and left/right rotation, assessed by a blinded investigator.
Time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Rehabilitation adherence
Adherence will be calculated as the number of completed prescribed rehabilitation sessions divided by the number of prescribed sessions during the corresponding assessment period, multiplied by 100%. Higher percentages indicate better adherence.
Time frame: Up to 1 month post-operation
Acceptability of postoperative rehabilitation
Acceptability of the postoperative rehabilitation program will be assessed using study-specific items addressing clarity of the rehabilitation guidance, usefulness of the educational materials, suitability, perceived safety, burden, confidence in recovery, overall satisfaction, and willingness to recommend the rehabilitation approach. Each item is rated on a 5-point Likert scale ranging from 1 (strongly disagree) to 5 (strongly agree).
Time frame: 30 days after drainage removal
Plan to share: No
No publications or documents are linked to this record.
Started Sep 2026 (actual). Primary completion is estimated for Dec 2028, 27 months after the start.
Of 126 non-industry interventional studies with no phase under Thyroid Neoplasms, half reached primary completion within 46 months of starting (the median), counting those still running; a quarter within 14 and three quarters within 78. This study's planned 27 months is below that.
Counting every sponsor, half of 127 studies reached it within 46 months; a quarter within 14 and three quarters within 78.
How these figures are worked out, and which studies are left out of them.
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Shanghai 6th People's Hospital