Thyroid Cancer, Papillary clinical trials
The registry lists 186 studies for Thyroid Cancer, Papillary across more than 10 countries. 51 are recruiting or about to start. 120 of them are mainly about Thyroid Cancer, Papillary (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
Get an email when these change. Save the Thyroid Cancer, Papillary studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
National Cancer Institute (NCI) (18) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (6) · Massachusetts General Hospital (4) · Fujian Medical University (4) · University Health Network, Toronto (4) · M.D. Anderson Cancer Center (4) · Hoffmann-La Roche (4) · Chinese PLA General Hospital (4)
What is being tested here
Drugs under test in Thyroid Cancer, Papillary studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Vemurafenib | 2 | 1 | 4 |
| Cobimetinib | 2 | 1 | 2 |
| Selpercatinib | 1 | 0 | 4 |
| Dabrafenib | 1 | 1 | 3 |
| Trametinib | 1 | 1 | 2 |
| Thyroxine | 1 | 0 | 2 |
| Sacituzumab tirumotecan | 1 | 0 | 1 |
| Mitoxantrone | 1 | 0 | 1 |
| Zanzalintinib | 1 | 0 | 1 |
| Iodine I-131 | 1 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 2 open · Angiogenesis inhibitors 4 · Immune checkpoint inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Iodine Status and Characteristics of Papillary Thyroid Cancer · Shandong Provincial Hospital
- Nov 2026Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation · City of Hope Medical Center
- Dec 2026Radiofrequency Ablation for Curative Treatment of Small Low-Risk Papillary Thyroid Cancer: Pilot Study · University Health Network, Toronto
- Dec 2026Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced Ultrasound · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Mar 2027Pattern and Surgical Outcome of Papillary Thyroid Cancer at Sohag University Hospitals · Sohag University
- Apr 2027The Role of Prophylactic Central Compartment Neck Dissection in the Management of 2 to 4 cm Papillary Thyroid Carcinoma · Leonardo Rossi
- Apr 2027The Clinical Outcomes and Prediction of Thermal Ablation for Low-risk Papillary Thyroid Carcinoma · Chinese PLA General Hospital
- May 2027Regret Emotion After Thyroidectomy in Low-Risk Papillary Thyroid Cancer · West China Hospital
- Jun 2027Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules · Ming-an Yu
- Jun 2027Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options · Hoffmann-La Roche
Who these studies take
Of the 33 Thyroid Cancer, Papillary studies recruiting now, 20 (61%) set no upper age limit and 8 (24%) stop at 75 or younger. 15 (45%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 10 (30%) | 10 (30%) |
| 18 | 33 (100%) | 33 (100%) |
| 30 | 33 (100%) | 33 (100%) |
| 40 | 33 (100%) | 33 (100%) |
| 50 | 33 (100%) | 33 (100%) |
| 65 | 32 (97%) | 32 (97%) |
| 75 | 26 (79%) | 26 (79%) |
| 85 | 22 (67%) | 22 (67%) |
Across all 186 studies, recruiting or not: 18% stop at 75 or younger and 8% at 65; 24% take children; 1% are for women only and 0% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Thyroid Cancer, Papillary studies take
Of 26 interventional studies with no phase under Thyroid Cancer, Papillary, half reached primary completion within 36 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 36 mo23–71 · 26 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
- Prophylactic Central Neck Dissection for Papillary Thyroid CarcinomaNov 3, 2026NCT07911761
- Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid CancerOct 30, 2026NCT07907432
Studies
Recruiting first, then most recently updated. Showing 50 of 186. Browse all 186 → or search them.
- Studies on Tumors of the ThyroidRecruitingNCT000011601 country
- Definition of Mutational Profile of Papillary Thyroid Tumors by Mass-ARRAYRecruitingNCT057660981 country
- Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid CancerNot yet recruitingNCT079074321 country
- Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA TrialNot yet recruitingNCT07529080Not applicable1 country
- Bethesda Classification and Risk Stratification in Differentiated Thyroid CarcinomaNot yet recruitingNCT07858097
- Pattern and Surgical Outcome of Papillary Thyroid Cancer at Sohag University HospitalsNot yet recruitingNCT07823439
- Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid CancersRecruitingNCT071407571 country
- DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.RecruitingNCT07440290Phase 2/31 country
- Sacituzumab Tirumotecan in Recurrent/Metastatic Adenoid Cystic Carcinoma and Papillary Thyroid Carcinoma (STRAP)Not yet recruitingNCT07521670Phase 24 countries
- Humanistic Continuing Care Via WeChat for Patients Undergoing Thermal Ablation of Papillary Thyroid CarcinomaRecruitingNCT07302672Not applicable1 country
- Health and Wellness Coaching to Improve Adherence to Healthy Habits and Treatment Plans in Papillary and Follicular Thyroid Cancer SurvivorsRecruitingNCT07545837Not applicable1 country
- XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid CancerRecruitingNCT06959641Phase 21 country
- Clinical Utility of Preoperative Thyroid GuidePx® TestingNot yet recruitingNCT07584447
- Radiofrequency Ablation for Curative Treatment of Small Low-Risk Papillary Thyroid Cancer: Pilot StudyRecruitingNCT07376837Not applicable1 country
- Surgical Competency for Robot-Assisted Thyroidectomy: Construction and Validation of a Robotic Thyroidectomy Assessment Score (RTAS)RecruitingNCT067303211 country
- The Role of Prophylactic Central Compartment Neck Dissection in the Management of 2 to 4 cm Papillary Thyroid CarcinomaNot yet recruitingNCT06899347Not applicable
- Decision Aid Efficacy in Low Risk Thyroid CancerNot yet recruitingNCT07536412Not applicable1 country
- The Clinical Outcomes and Prediction of Thermal Ablation for Low-risk Papillary Thyroid CarcinomaRecruitingNCT063168951 country
- Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E MutationRecruitingNCT06440850Phase 21 country
- Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced UltrasoundRecruitingNCT073575711 country
- Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer SurgeryNot yet recruitingNCT07354698Phase 41 country
- Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical SamplesRecruitingNCT061333741 country
- Multimodal Deep Learning for Lymph Node Metastasis in Thyroid CancerNot yet recruitingNCT072993181 country
- Comparative Study of Transaxillary Robotic Thyroidectomy With MRND Versus Conventional Open Surgery in N1b PTCRecruitingNCT06623578Not applicable1 country
- DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.RecruitingNCT05768178Phase 2/31 country
- Targeted Therapy to Increase RAI Uptake in Metastatic DTCRecruitingNCT050249292 countries
- RET-US Study - Ultrasound-Based Prediction of RET Alterations and Lateral-Neck Metastasis in Thyroid CancerNot yet recruitingNCT070429841 country
- Intraoperative Neuromuscular Monitoring and Its Impact on Pre- and Postoperative Acoustic Outcomes in Thyroid SurgeryRecruitingNCT062548591 country
- Necessity of TSH Suppression Therapy in Active Surveillance for Thyroid Cancer Patients.Not yet recruitingNCT06971965Not applicable
- Active Surveillance for Low-risk Papillary Thyroid CarcinomaEnrolling by invitationNCT062611901 country
- Shared Decision-Making for Determining Treatment Strategies in Low-Risk Thyroid CancerNot yet recruitingNCT06730893Not applicable
- Ultrasound-guided Thermal Ablation for Papillary Thyroid CarcinomaRecruitingNCT067337401 country
- Regret Emotion After Thyroidectomy in Low-Risk Papillary Thyroid CancerNot yet recruitingNCT06804863Not applicable1 country
- A Study of Online Follow-up in Patients with Papillary Thyroid CancerRecruitingNCT06800482Not applicable1 country
- A Clinical Study on the Benefits of Carbon Nanoparticles Injection Time in Patients With Thyroid Cancer.RecruitingNCT06791005Phase 31 country
- Ultrasound-Guided Microwave Ablation Vs. Surgery for Low-Risk PapilaryThyroid CarcinomaRecruitingNCT067255761 country
- Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TCRecruitingNCT05668962Phase 21 country
- Multiomics Study of Biological Behavior of Lymph Node Metastasis in Papillary Thyroid CarcinomaNot yet recruitingNCT06725628
- Iodine Status and Characteristics of Papillary Thyroid CancerNot yet recruitingNCT06626581
- Single-Incision Gasless Endoscopic Total Thyroidectomy Via Subclavian Approach Versus Open Surgery for PTCRecruitingNCT065927551 country
- Health-Related Quality of Life and Emotions in Patients with Thyroid NodulesRecruitingNCT066106041 country
- Improvements in Thyroid Tumor Surgery and the Prognosis, Diagnosis, Recurrence and Metastasis of PatientsRecruitingNCT06468696Not applicable1 country
- Treatment Efficacy and Safety of Low-dose Radioiodine Ablation for Intermediate-risk Differentiated Thyroid CarcinomaRecruitingNCT04354324Not applicable1 country
- Prediction of Lymph Node Metastasis in Patients With Thyroid Malignancy by a New ScaleRecruitingNCT062866311 country
- AI-Based Multimodal Multi-tasks Analysis Reveals Tumor Molecular Heterogeneity, Predicts Preoperative Lymph Node Metastasis and Prognosis in Papillary Thyroid CarcinomaRecruitingNCT062410921 country
- A Study of Factors Influencing Recurrence After Thermal Ablation of Papillary Thyroid CarcinomaRecruitingNCT059628921 country
- Effects of Radioactive Iodine on the Immune System in Thyroid CancerNot yet recruitingNCT059895551 country
- A Clinical Study of Transaxillary Endoscopic and Open Thyroidectomy for PTCRecruitingNCT05545852Not applicable1 country
- Proteomics of Papillary Thyroid CarcinomaRecruitingNCT028140321 country
- Cross-sectional Case and Control Study on Quality of Life, Appearance and Functions in PTC Via Different Surgical ApproachRecruitingNCT059321211 country