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RecruitingNCT06592755Updated Oct 1, 2024

Single-Incision Gasless Endoscopic Total Thyroidectomy Via Subclavian Approach Versus Open Surgery for PTC

An observational study in Papillary Thyroid Carcinoma, sponsored by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University. Recruiting at 1 site in China. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2024-10-01.

Sponsored by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Observational

From the registry’s dates

  • Primary completion was expected by Sep 2024, 2 years ago, but the record still lists the study as recruiting.
  • Started Sep 2024; still recruiting 2 years later.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
120
Ages
18 Years to 70 Years
Sex
All
01

Study summary

Historically, performing a contralateral thyroid lobectomy and lymph node dissection via the subclavian approach was considered challenging. This study aimed to evaluate the safety and feasibility of single-incision gasless endoscopic total thyroidectomy and central compartment neck dissection via the subclavian approach (SCA) in comparison to conventional open surgery for the treatment of papillary thyroid carcinoma (PTC) retrospectively.

Read the detailed description

Historically, performing a contralateral thyroid lobectomy and lymph node dissection via the subclavian approach was considered challenging. This study aimed to evaluate the safety and feasibility of single-incision gasless endoscopic total thyroidectomy and central compartment neck dissection via the subclavian approach (SCA) in comparison to conventional open surgery for the treatment of papillary thyroid carcinoma (PTC) retrospectively.

02

Conditions studied

  • Papillary Thyroid Carcinoma
03

In context

Carcinoma

6,741 studies on the registry are indexed under Carcinoma; 1,161 are open to participants now.

This study's planned enrollment of 120 is below the median of 149 across 1,175 observational studies indexed under Carcinoma.

Browse Carcinoma studies →

Lead sponsor

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University is the lead sponsor of 466 studies on the registry; 271 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The patients, who were diagnosed with papillary thyroid carcinoma at our center, chose to undergo either single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection via the subclavian approach or conventional open surgery.

Inclusion criteria

  • (1) thyroid neoplasm \<3.0 cm;
  • (2) well differentiated papillary thyroid carcinoma.

Exclusion criteria

Exclusion Criteria:

  • (1) extrathyroidal extensions estimated in ultrasonography scan;
  • (2) enlarged lymph nodes in lateral neck compartment on palpation, or US scan;
  • (3) suspected distant metastases;
  • (4) previous history of neck radiation therapy and/or surgery.
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
120 participants (estimated)
Patient registry
No

Groups and cohorts

  • the Subclavian Approach group

    The patients chose to undergo total thyroidectomy and central compartment neck dissection via the single-incision subclavian approach.

    Procedure: single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection

  • the conventional open surgery group

    The patients chose to undergo total thyroidectomy and central compartment neck dissection via the conventional open surgery approach.

    Procedure: conventional open surgery

Interventions

  • Proceduresingle-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection

    The included patients chose to undergo single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection via the subclavian approach based on patients preference.

  • Procedureconventional open surgery

    These patients chose to undergo total thyroidectomy with central compartment neck dissection via conventional open surgery based on patients preference.

06

What researchers measure

Primary outcomes

  1. the disease-free survival

    The disease-free survival refers to the probability of survival without any biologic, structural, or functional events.

    Time frame: up to 24 months

07

Study locations

1 of 1 sites recruiting
  • Sun Yat-sen Memorial Hospital
    Guangzhou, Guangdong 510120, China
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 1, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06592755
Lead sponsor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Responsible party
Sponsor
First posted
Sep 19, 2024
Start date
Sep 20, 2024
Primary completion
Sep 30, 2024 (estimated)
Completion
Sep 30, 2024 (estimated)
Last update
Oct 1, 2024

Study contacts

Lin
Contact
linpliang3@mail.sysu.edu.cn
0086-020-34071439
View the source record on ClinicalTrials.gov ↗

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