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Tetralogy of Fallot clinical trials

The registry lists 92 studies for Tetralogy of Fallot across more than 10 countries. 25 are recruiting or about to start. 65 of them are mainly about Tetralogy of Fallot (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.

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Status

Completed
39
Recruiting
17
Status unknown
14
Not yet recruiting
8
Active, not recruiting
8
Terminated
4

Phase

Phase 1
5
Phase 2
5
Phase 3
3
Phase 4
2
Early Phase 1
1

Where

United States
32
Canada
9
Germany
9
France
7
China
6
Netherlands
5

Who runs them

Edwards Lifesciences (4) · Assiut University (4) · Boston Children's Hospital (4) · Emory University (3) · Competence Network for Congenital Heart Defects (3) · Rigshospitalet, Denmark (2) · Athena Zuppa (2) · Beijing Anzhen Hospital (2)

What is being tested here

Drugs under test in Tetralogy of Fallot studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Propranolol101
Dexmedetomidine015
Sulfur Hexafluoride001
Alpha-Tocopherol001
Cyclosporine001
Fentanyl001
Eplerenone001
Losartan001

Coming up

0phase 3 studies under way
7studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 7

Who these studies take

Of the 17 Tetralogy of Fallot studies recruiting now, 8 (47%) set no upper age limit and 9 (53%) stop at 75 or younger. 13 (76%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (6%) take healthy volunteers.

Recruiting studies that take each age, of 17
AgeWomenMen
107 (41%)7 (41%)
1811 (65%)11 (65%)
309 (53%)9 (53%)
409 (53%)9 (53%)
508 (47%)8 (47%)
658 (47%)8 (47%)
758 (47%)8 (47%)
858 (47%)8 (47%)

Across all 92 studies, recruiting or not: 41% stop at 75 or younger and 40% at 65; 75% take children; 0% are for women only and 1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Tetralogy of Fallot studies take

Of 25 interventional studies with no phase under Tetralogy of Fallot, half reached primary completion within 35 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase35 mo23–61 · 25 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 15, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 92. Browse all 92 → or search them.