Our grouping. This page groups the registry's lead sponsor names by company — our grouping, not the registry's. It can be wrong or incomplete: an acquired company whose name never mentions its owner may be missing. Use “Something wrong?” under any name below to correct it.
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Edwards Lifesciences clinical trials
The registry lists 141 studies whose lead sponsor is Edwards Lifesciences or one of 5 companies grouped under it. 22 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 21, 2026.
Keep track of what changes. Save the Edwards Lifesciences studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesRegistry sponsor names on this page
Each name exactly as ClinicalTrials.gov lists it, and how it relates to Edwards Lifesciences.
- Edwards Lifesciences128 studiesSame company
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- Endotronix, Inc.6 studies →Acquired — became part of Edwards Lifesciences, Aug 19, 2024 · source ↗
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- JC Medical, Inc., an affiliate of Edwards Lifesciences LLC3 studies →Acquired — became part of Edwards Lifesciences, Jul 22, 2024 · source ↗
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- JC Medical, Inc.2 studies →Acquired — became part of Edwards Lifesciences, Jul 22, 2024 · source ↗
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- Edwards (Shanghai) Lifesciences Medical Supplies Co., Ltd.1 study →Subsidiary
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- Innovalve Bio Medical Ltd.1 study →Acquired — became part of Edwards Lifesciences, Oct 1, 2024 · source ↗
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Focus areas
Conditions Edwards Lifesciences leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Studies
Recruiting first, then most recently updated. Showing 50 of 141. Browse all 141 →
- TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study)RecruitingNCT07684313
- ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic ValvesRecruitingNCT05172973Not applicable
- The CLASP III TR CED StudyNot yet recruitingNCT07859709
- Early Feasibility Study of the Edwards APTURE Transcatheter Shunt SystemRecruitingNCT07858799Not applicable
- Early Feasibility Study - Edwards APTURE Transcatheter Shunt SystemRecruitingNCT03523416Not applicable
- Real World Data Collection on the INSPIRIS RESILIA Aortic ValveRecruitingNCT07120048
- KONECT RESILIA Aortic Valved Conduit (AVC) Real-world Study Assessing Safety and PerformanceRecruitingNCT07619872
- TTVR STRONG Under Coverage With Evidence Development (CED) StudyRecruitingNCT06833476
- ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart ValveRecruitingNCT05172960Not applicable
- TVMR With the INNOVALVE System Trial - Early Feasibility StudyRecruitingNCT04919980Not applicable
- Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical TrialRecruitingNCT04097145Not applicable
- Real World European Investigation of Safety and Clinical Efficacy of the EVOQUE System (TRISCEND III EU)RecruitingNCT06569602
- CLAARITY is a Prospective, Observational, Single-arm, Multi-center, Post-market US Study Designed to Evaluate the Safety and Performance of the ECLIPTIS Left Atrial Appendage Exclusion System for Exclusion of the Left Atrial Appendage (LAA) During Concomitant Open-heart Cardiac Surgery.Not yet recruitingNCT07742839
- COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionRecruitingNCT02744677Not applicable
- PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and IIIRecruitingNCT05934487Not applicable
Sponsor listed in the registry: Endotronix, Inc. · First submitted before Endotronix, Inc. became part of Edwards Lifesciences
- J-Valve Transfemoral Pivotal StudyRecruitingNCT06455787Not applicable
Sponsor listed in the registry: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC · First submitted before JC Medical, Inc. became part of Edwards Lifesciences
- JOURNEY LVAD: JOURNEY Left Ventricular Assist DeviceNot yet recruitingNCT07363473Not applicable
Sponsor listed in the registry: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC · First submitted after JC Medical, Inc. became part of Edwards Lifesciences
- MITRIS China Post Market Clinical Follow-up (PMCF) StudyRecruitingNCT07059793
- ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - MitralNot yet recruitingNCT06167213Not applicable
- PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVRRecruitingNCT04889872Not applicable
- Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart FailureRecruitingNCT06783335
Sponsor listed in the registry: Endotronix, Inc. · First submitted after Endotronix, Inc. became part of Edwards Lifesciences
- PARTNER 3 Trial - Aortic Valve-in-ValveRecruitingNCT03003299Not applicable
- Autus Valve Pivotal StudyActive, not recruitingNCT05006404Not applicable
- ALTERRA: SAPIEN 3 THV With the Alterra Adaptive PrestentActive, not recruitingNCT03130777Not applicable
- Autus Valve Continued Access Study (CAS)Active, not recruitingNCT07466745Not applicable
- Transcatheter Repair of Tricuspid Regurgitation With Edwards Cardioband TR System Post Market Study (TriBAND)Active, not recruitingNCT03779490
- The ENCIRCLE TrialActive, not recruitingNCT04153292Not applicable
- ALTERRA Post-Approval StudyActive, not recruitingNCT05378386
- INSPIRIS China PMCF StudyActive, not recruitingNCT05404880
- SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral RegurgitationCompletedNCT03230747Not applicable
- MiCLASP Post Market Clinical Follow-Up (PMCF) StudyActive, not recruitingNCT04430075
- Beating Heart Mitral Valve Repair With the HARPOON™ SystemActive, not recruitingNCT04375332Not applicable
- China S3 PMS: SAPIEN 3 China Post Market Registry StudyActive, not recruitingNCT05168826
- INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance StudySuspendedNCT04902053
- SIRONA 2 Trial Heart Failure NYHA Class IIIActive, not recruitingNCT04012944Not applicable
Sponsor listed in the registry: Endotronix, Inc. · First submitted before Endotronix, Inc. became part of Edwards Lifesciences
- PROACTIVE-HF IDE Trial Heart Failure NYHA Class IIIActive, not recruitingNCT04089059Not applicable
Sponsor listed in the registry: Endotronix, Inc. · First submitted before Endotronix, Inc. became part of Edwards Lifesciences
- Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair SystemActive, not recruitingNCT04614402
- Edwards CLASP TR EFSCompletedNCT03745313Not applicable
- Edwards PASCAL CLASP IID/IIF Pivotal Clinical TrialActive, not recruitingNCT03706833Not applicable
- HPI (Hypotension Prediction Index) Care TrialTerminatedNCT05083403Not applicable
- ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt SystemActive, not recruitingNCT05686317Not applicable
- Real-world Clinical Outcomes of the MITRIS RESILIA Mitral ValveActive, not recruitingNCT05526560
- Clinical Study of Edwards Cardioband FIT Valve Repair SystemActive, not recruitingNCT03382457Not applicable
- 2019-06 TRISCEND StudyActive, not recruitingNCT04221490Not applicable
- ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)CompletedNCT01757665Not applicable
- SAPIEN 3 Ultra System PMCFActive, not recruitingNCT04555967
- Edwards EVOQUE Eos MISCEND StudyActive, not recruitingNCT02718001Not applicable
- TRISCEND II Pivotal TrialActive, not recruitingNCT04482062Not applicable
- The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System StudyCompletedNCT03170349Not applicable
- COMPASSION S3 Post-Approval StudyActive, not recruitingNCT04860765