Stress Disorders, Traumatic, Acute clinical trials
The registry lists 58 studies for Stress Disorders, Traumatic, Acute across more than 10 countries. 15 are recruiting or about to start. 30 of them are mainly about Stress Disorders, Traumatic, Acute (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-22.
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· Enrollment: 300 → 450 participants
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Who runs them
University of North Carolina, Chapel Hill (3) · Biologische Heilmittel Heel GmbH (3) · Centre Hospitalier Universitaire Vaudois (2) · Walter Reed Army Institute of Research (WRAIR) (2) · Karolinska Institutet (2) · Douglas Mental Health University Institute (2) · Texas State University (2) · Hospices Civils de Lyon (2)
What is being tested here
Drugs under test in Stress Disorders, Traumatic, Acute studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Nov 2026Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL) · University of North Carolina, Chapel Hill
- Mar 2027Promoting Improved Functioning Among People Experiencing Stressful Situations · University of North Carolina, Chapel Hill
- Apr 2027Adolescent Stress and Substance Intervention Subsequent to Trauma · Rhode Island Hospital
- May 2027Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety · University of Texas at Austin
- Sep 2027The Efficacy of Vitamin D Supplementation to Sustain Performance Outcomes · Walter Reed Army Institute of Research (WRAIR)
Who these studies take
Of the 9 Stress Disorders, Traumatic, Acute studies recruiting now, 2 (22%) set no upper age limit and 7 (78%) stop at 75 or younger. 1 (11%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 7 (78%) | 7 (78%) |
| 30 | 8 (89%) | 8 (89%) |
| 40 | 8 (89%) | 8 (89%) |
| 50 | 6 (67%) | 6 (67%) |
| 65 | 4 (44%) | 4 (44%) |
| 75 | 2 (22%) | 2 (22%) |
| 85 | 2 (22%) | 2 (22%) |
Across all 58 studies, recruiting or not: 52% stop at 75 or younger and 47% at 65; 17% take children; 3% are for women only and 3% for men only; 48% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Stress Disorders, Traumatic, Acute studies take
Of 25 interventional studies with no phase under Stress Disorders, Traumatic, Acute, half reached primary completion within 16 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 16 mo7–35 · 25 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 58. Browse all 58 → or search them.
- Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)RecruitingNCT06636786Phase 21 country
- Assessment of the Preventive Effect of Defusing on Traumatic KindlingNot yet recruitingNCT07850193Not applicable1 country
- Integrative Medicine for Hospital Workers Exposed to WarRecruitingNCT06190964Not applicable1 country
- The Efficacy of Vitamin D Supplementation to Sustain Performance OutcomesRecruitingNCT07654777Not applicable1 country
- Cannabidiol (CBD) and Stress Response: Psychobiological MechanismsRecruitingNCT07069478Not applicable1 country
- Adolescent Stress and Substance Intervention Subsequent to TraumaRecruitingNCT07197476Not applicable1 country
- Early Intervention to Prevent Development of PTSD in Burn Survivors and Their CaregiversNot yet recruitingNCT07656545Not applicable1 country
- The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance OutcomesRecruitingNCT06982183Phase 41 country
- BXCL501 After Stress to Increase Recovery SuccessRecruitingNCT06943404Phase 21 country
- Impact of MetaCalm on Stress of Healthy People With Acute StressNot yet recruitingNCT07507669Not applicable1 country
- Promoting Improved Functioning Among People Experiencing Stressful SituationsRecruitingNCT06482567Not applicable1 country
- Respiratory Training in the Treatment of Transdiagnostic Pathological AnxietyRecruitingNCT05427708Not applicable1 country
- Internet-delivered Trauma-focused Cognitive-behavioral Therapy as an Early Intervention After Sexual TraumaNot yet recruitingNCT06502106Not applicable1 country
- Condensed Digital Prolonged Exposure for Individuals Treated Within Somatic Trauma Care.Not yet recruitingNCT06318195Not applicable1 country
- Feasibility Study of the Self-Care Immediate Stabilization Procedure (ISP) ® After a Traumatic ExperienceNot yet recruitingNCT06277973Not applicable1 country
- Breathwork and Stress: Investigating the Mechanisms of Action and Effectiveness of Breathing Interventions in Modulating the Psychophysiological Response to Acute Stress TestCompletedNCT07529379Not applicable1 country
- Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving IncarcerationCompletedNCT04785677Not applicable1 country
- Impact of Repeated Virtual Reality Training on Markers of StressCompletedNCT07770880Not applicable1 country
- Racial Discrimination and Stress ResponseCompletedNCT05820659Not applicable1 country
- EMDR Flash Group Protocol for Earthquake SurvivorsCompletedNCT07672613Not applicable1 country
- Efficacy of Prazosin in Preventing Post-traumatic Stress DisorderCompletedNCT03045016Phase 21 country
- DEPITAC : Short Screening Scale for Psychotraumatic Disorders After Motor Vehicle AccidentCompletedNCT012006281 country
- PTSD Prevention Using Oral HydrocortisoneCompletedNCT04924166Phase 22 countries
- Removing Surrogates' Uncertainty to Reduce Fear and Anxiety After Cardiac EventsCompletedNCT06048068Not applicable1 country
- Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency RoomWithdrawnNCT05057689Phase 21 country
- Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress ReactionCompletedNCT06390267Not applicable1 country
- Neuronal Correlates of Neurexan® Action in Mildly to Moderately Stressed ProbandsCompletedNCT02602275Phase 21 country
- Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on HealthCompletedNCT052067341 country
- The Effect of Breathing on Cognitive Performance and StressCompletedNCT06986135Not applicable1 country
- The Visiting Child and His Family in ICUCompletedNCT03954522Not applicable1 country
- Digital Interventions to Understand and Mitigate Stress ResponseCompletedNCT05923398Not applicable1 country
- Implementation of a Minor Ailment Service in Community Pharmacy PracticeCompletedNCT05247333Not applicable1 country
- Needs, Perceptions and Acute Stress of Healtcare Workers Caring for COVID-19 Patients in South AmericaCompletedNCT044864045 countries
- Swiss TrAumatic biRth TrialCompletedNCT03576586Not applicable1 country
- Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological TraumaStatus unknownNCT04982211Phase 21 country
- Dexmedetomidine Combined With Hydromorphone in Tonsillectomy and AdenoidectomyCompletedNCT03760809Phase 41 country
- Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 OperatorsStatus unknownNCT03152175Phase 21 country
- Micro-Dose, Macro-Impact: Leveraging Psychedelics in Frontline Healthcare Workers During the COVID-19 PandemicStatus unknownNCT04769297Phase 41 country
- Mindful Melody: Feasibility of Implementing Music Listening on an Inpatient Psychiatric Unit and Its Relation to the Use of As Needed Medications for Acute AgitationCompletedNCT045144321 country
- Preemptive Chlorepheniramine Maleate Reducing Postoperative AgitationCompletedNCT04293081Not applicable1 country
- Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation?CompletedNCT03862391Phase 41 country
- GASA-CIR Trail (Guidance and the Symptoms of Acute Stress and Anxiety in Critically Ill Patients Relatives in Intensive Care Unit)Status unknownNCT03812458Not applicable1 country
- Post-traumatic Stress Injuries Among Paramedics and Emergency DispatchersStatus unknownNCT04202042Not applicable1 country
- Prevention of Post Traumatic Stress Disorder Following Trauma by Attention Control TrainingCompletedNCT02591485Not applicable1 country
- Neurophysiological Mechanisms of Accelerated Resolution Therapy (ART)Status unknownNCT04121884Not applicable1 country
- Intranasal Neuropeptide Y in Clinical Trial in Level Two Trauma Patients for PTSD and Acute Stress DisorderStatus unknownNCT04071600Phase 1/21 country
- Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral TherapyCompletedNCT00889005Not applicable1 country
- Intensiva 2.0: Improve the Communication Towards Families of Critically Ill PatientsStatus unknownNCT03438175Not applicable1 country
- Effect of Nature Based Sounds' Intervention on Agitation and Anxiety of Patients Admitted in Intensive Care Units.CompletedNCT03213782Not applicable
- Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical ProtocolTerminatedNCT01013870Phase 21 country