Speech clinical trials
The registry lists 205 studies for Speech across more than 10 countries. 80 are recruiting or about to start. 67 of them are mainly about Speech (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Speech Intelligibility too: 231 studies, 88 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Novoic Limited (8) · New York University (8) · Yale University (8) · University of Florida (5) · University of Wisconsin, Madison (5) · University of California, San Francisco (5) · Shirley Ryan AbilityLab (4) · National Institute on Deafness and Other Communication Disorders (NIDCD) (4)
What is being tested here
Drugs under test in Speech studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| VX-745 | 0 | 0 | 1 |
| Ebselen | 0 | 0 | 1 |
| Cycloserine | 0 | 0 | 1 |
| Mifepristone | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Vowel Space Expansion Sensorimotor Adaptation · University of Wisconsin, Madison
- Nov 2026Impact of Anterior Cross Bite Treatment on Children's Speech Performance · Tanta University
- Nov 2026Exploring Lived Experiences of Families of Children With Spinal Muscular Atrophy(SMA) Type 1 Regarding Feeding and Communication · Guy's and St Thomas' NHS Foundation Trust
- Dec 2026Virtual Reality as a Tool for Training Public Speaking Skills in Higher Education Students · University of Liege
- Dec 2026Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation. · Old Dominion University
- Dec 2026Feasibility of Early Swallowing and Speech Intervention for Head and Neck Cancer Patients Treated SURGically · University Health Network, Toronto
- Dec 2026SPEECH as Biomarker for Emotion, Movement and cOgnition in Parkinson's Disease · Insel Gruppe AG, University Hospital Bern
- Jan 2027taVNS for Speech and Language Recovery in Aphasia · University of Florida
- Feb 2027TOngue/Palate Interactions Study · Hospices Civils de Lyon
- Feb 2027Dysarthria Management for Minor Groups · Florida State University
Who these studies take
Of the 56 Speech studies recruiting now, 22 (39%) set no upper age limit and 28 (50%) stop at 75 or younger. 24 (43%) take children under 18. 1 (2%) are for women only and 0 (0%) for men only; 21 (38%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 14 (25%) | 13 (23%) |
| 18 | 30 (54%) | 30 (54%) |
| 30 | 35 (63%) | 35 (63%) |
| 40 | 33 (59%) | 33 (59%) |
| 50 | 32 (57%) | 32 (57%) |
| 65 | 32 (57%) | 32 (57%) |
| 75 | 31 (55%) | 31 (55%) |
| 85 | 27 (48%) | 27 (48%) |
Across all 205 studies, recruiting or not: 51% stop at 75 or younger and 43% at 65; 35% take children; 1% are for women only and 1% for men only; 46% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Speech studies take
Of 90 interventional studies with no phase under Speech, half reached primary completion within 45 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 45 mo15–65 · 90 studies | — | 45 mo14–65 · 85 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 205. Browse all 205 → or search them.
- VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication RestorationRecruitingNCT07224256Not applicable1 country
- Neural Mechanisms for Stopping Ongoing Speech Production (Study 2)Enrolling by invitationNCT07713706Not applicable1 country
- Treatment Targets in Spanish and English Bilingual Speech InterventionRecruitingNCT06416306Phase 11 country
- Visual-acoustic Intervention With Service Delivery In-person and Via Telepractice TrialRecruitingNCT06517225Phase 21 country
- Collection of Clinical Data and Specimens for Research in Hearing, Balance, Taste, Smell, Voice, Speech, and Language Disorders.RecruitingNCT056704961 country
- Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who StutterRecruitingNCT07354139Not applicable1 country
- Vowel Space Expansion Sensorimotor AdaptationRecruitingNCT06233513Not applicable1 country
- STIMPulseControl Ancillary Speech StudyRecruitingNCT06561919Not applicable3 countries
- Transcranial Stimulation Combined With Auditory TrainingRecruitingNCT06738030Not applicable1 country
- Neurofilament Light Chain And Voice Acoustic Analyses In Dementia DiagnosisRecruitingNCT063391901 country
- Impact of Anterior Cross Bite Treatment on Children's Speech PerformanceRecruitingNCT06168695Not applicable1 country
- NIDCD Otolaryngology Clinical Protocol Biospecimen BankRecruitingNCT063031801 country
- Understanding Speech in Background NoiseEnrolling by invitationNCT07822802Not applicable1 country
- Dynamic Neural Mechanisms of Audiovisual Speech PerceptionEnrolling by invitationNCT04290130Not applicable1 country
- Speech Motor Learning and Retention (Master Protocol)RecruitingNCT06467292Not applicable1 country
- Speech Production Enhancement Using Augmentative Communication for KidsRecruitingNCT07173049Not applicable1 country
- Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy.Not yet recruitingNCT077397711 country
- Non-Invasive Brain Stimulation to Improve Language in Down Syndrome.RecruitingNCT07044804Not applicable1 country
- The Impact of Deep Brain Stimulation on Speech and Swallow Function in Parkinson DiseaseRecruitingNCT07026734Not applicable1 country
- Speech Motor Learning and Retention (Aim 3)RecruitingNCT06492252Not applicable1 country
- Neural Prediction to Enhance LanguageRecruitingNCT05962359Not applicable1 country
- Functional Organization of the Superior Temporal Gyrus for Speech PerceptionEnrolling by invitationNCT05435859Not applicable1 country
- Posture, Tongue Position and PronunciationNot yet recruitingNCT07650734Not applicable
- Feasibility of Early Swallowing and Speech Intervention for Head and Neck Cancer Patients Treated SURGicallyRecruitingNCT06192771Not applicable1 country
- Exploring Lived Experiences of Families of Children With Spinal Muscular Atrophy(SMA) Type 1 Regarding Feeding and CommunicationNot yet recruitingNCT075962771 country
- SPEECH as Biomarker for Emotion, Movement and cOgnition in Parkinson's DiseaseRecruitingNCT05765110Not applicable2 countries
- Targeted Transcranial Magnetic Stimulation to Improve Language and Speech in Patients With Primary Progressive AphasiaEnrolling by invitationNCT06921265Not applicable1 country
- Speech Amplification Devices for Parkinson Disease: Talker- and Technology-Driven EnhancementsRecruitingNCT07599696Not applicable1 country
- Generalization With AI Navigation Using StaRtRecruitingNCT06884943Phase 21 country
- Clinical Feasibility & Validation of the Virtual Reality GlenxRose Speech-Language TherapiesRecruitingNCT05695131Not applicable1 country
- taVNS for Speech and Language Recovery in AphasiaEnrolling by invitationNCT07563387Not applicable1 country
- Listener Training for Improved Intelligibility of People With Parkinson's DiseaseRecruitingNCT06815263Not applicable1 country
- Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.RecruitingNCT05635929Not applicable1 country
- Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)RecruitingNCT07357428Not applicable1 country
- Promoting Early Intervention Timing and Attention to LanguageRecruitingNCT05853861Not applicable1 country
- Velopharyngeal Insufficiency After Maxillomandibular Advancement Osteotomy in Obstructive Sleep Apnea PatientsNot yet recruitingNCT073010211 country
- Research on Speech Development Trajectories and Predictive Models in Children With Autism Spectrum DisorderNot yet recruitingNCT07472829
- Chinese-Specific Speech Imagery Coding Using High-Density ECoGRecruitingNCT07460037Not applicable1 country
- Effectiveness of Ultrasound-Aided Articulation Therapy for Children With Speech Sound DisordersRecruitingNCT06831396Not applicable1 country
- Speech Motor Learning and Retention (Aim 2)RecruitingNCT06491823Not applicable1 country
- Speech Motor Learning and Retention (Aim 1)RecruitingNCT06467305Not applicable1 country
- The Signature of Alzheimer's Disease in Subjective Cognitive DeclineRecruitingNCT074021611 country
- Virtual Reality as a Tool for Training Public Speaking Skills in Higher Education StudentsRecruitingNCT07392554Not applicable1 country
- Adaptation of Pediatric Speech Audiometry Tests Into Other LanguagesRecruitingNCT071568251 country
- Longitudinal Assessment of Early Premature Infant Skills for Audiovisual Speech PerceptionNot yet recruitingNCT07245693Not applicable1 country
- Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation.Not yet recruitingNCT07219901Not applicable1 country
- Transient Ischemic Attack (TIA) and Spoken LanguageNot yet recruitingNCT072064331 country
- The Neural Coding of Speech Across Human LanguagesEnrolling by invitationNCT05014841Not applicable1 country
- Intelligibility and Acoustic Speech Performance of CAD/CAM Milled Titanium Partial DenturesRecruitingNCT06589570Not applicable1 country
- Talk With Me Baby to Enhance the Early Home Language EnvironmentRecruitingNCT06479278Not applicable1 country