Small Cell Lung Carcinoma: all 1,234 studies

Page 5 of 13. Open to participants first (350), then studies with results posted, then the rest; newest registration first within each.

• A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid TumorsCompletedNCT03708328Phase 1Results posted
• Study of Durvalumab + Tremelimumab, Durvalumab, and Placebo in Limited Stage Small-Cell Lung Cancer in Patients Who Have Not Progressed Following Concurrent Chemoradiation TherapyActive, not recruitingNCT03703297Phase 3Results posted
• Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung CancerTerminatedNCT03662074Phase 2Results posted
• Tumor-Treating Fields Therapy in Preventing Brain Tumors in Participants With Extensive-Stage Small Cell Lung CancerTerminatedNCT03607682Not applicableResults posted
• Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic TumorsCompletedNCT03583086Phase 1/2Results posted
• M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung CancersCompletedNCT03554473Phase 1/2Results posted
• Radiosurgery Plus NovoTTF-200A for Metastatic Small Cell Lung Cancer to the BrainTerminatedNCT03488472Not applicableResults posted
• SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard TherapyCompletedNCT03417895Phase 2Results posted
• Combination Immunotherapy-Ipilimumab-Nivolumab-Dendritic Cell p53 Vac - Patients With Small Cell Lung Cancer (SCLC)TerminatedNCT03406715Phase 2Results posted
• Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain MetastasesActive, not recruitingNCT03391362Not applicableResults posted
• Cisplatin/Carboplatin and Etoposide With or Without Nivolumab in Treating Patients With Extensive Stage Small Cell Lung CancerCompletedNCT03382561Phase 2Results posted
• Navitoclax and Vistusertib in Treating Patients With Relapsed Small Cell Lung Cancer and Other Solid TumorsTerminatedNCT03366103Phase 1/2Results posted
• PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic MalignanciesCompletedNCT03365791Phase 2Results posted
• Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.CompletedNCT03345485Phase 1/2Results posted
• Nivolumab and 177Lu-DOTA0-Tyr3-Octreotate for Patients With Extensive-Stage Small Cell Lung CancerCompletedNCT03325816Phase 1/2Results posted
• Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With CancerCompletedNCT03154190Not applicableResults posted
• Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic MalignanciesCompletedNCT03126110Phase 1/2Results posted
• Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung CancerCompletedNCT03098030Phase 2/3Results posted
• A Study of AK-01 (LY3295668) in Solid TumorsCompletedNCT03092934Phase 1/2Results posted
• Study of Irinotecan Liposome Injection (ONIVYDE®) in Patients With Small Cell Lung CancerCompletedNCT03088813Phase 3Results posted
• A Study of Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)CompletedNCT03066778Phase 3Results posted
• Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)CompletedNCT03061812Phase 3Results posted
• Durvalumab ± Tremelimumab in Combination With Platinum Based Chemotherapy in Untreated Extensive-Stage Small Cell Lung Cancer (CASPIAN)Active, not recruitingNCT03043872Phase 3Results posted
• Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung CancerCompletedNCT03043599Phase 1/2Results posted
• Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLCCompletedNCT03041311Phase 2Results posted
• A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)TerminatedNCT03033511Phase 3Results posted
• A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung CancerTerminatedNCT03026166Phase 1/2Results posted
• Pembrolizumab vs Topotecan in Patients With Small Cell Lung CancerTerminatedNCT02963090Phase 2Results posted
• A Phase II, Study to Determine the Preliminary Efficacy of Novel Combinations of Treatment in Patients With Platinum Refractory Extensive-Stage Small-Cell Lung CancerCompletedNCT02937818Phase 2Results posted
• PEN-221 in Somatostatin Receptor 2 Expressing Advanced Cancers Including Neuroendocrine and Small Cell Lung CancersCompletedNCT02936323Phase 1/2Results posted
• Study of Pembrolizumab and Chemotherapy With or Without Radiation in Small Cell Lung Cancer (SCLC)TerminatedNCT02934503Phase 2Results posted
• Olaparib, Cediranib Maleate, and Standard Chemotherapy in Treating Patients With Small Cell Lung CancerTerminatedNCT02899728Phase 2Results posted
• Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung CancerTerminatedNCT02769962Phase 1/2Results posted
• Nab-Paclitaxel With Gemcitabine for Relapsed Small Cell CancerCompletedNCT02769832Phase 2Results posted
• A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)CompletedNCT02763579Phase 3Results posted
• Carboplatin Plus Etoposide With or Without MPDL3280A in Untreated Extensive Stage Small Cell Lung CancerTerminatedNCT02748889Phase 1/2Results posted
• A Study of Prexasertib (LY2606368) in Participants With Extensive Stage Disease Small Cell Lung CancerCompletedNCT02735980Phase 2Results posted
• A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.Active, not recruitingNCT02734004Phase 1/2Results posted
• An Open-Label, Dose-Escalation/Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced MalignanciesTerminatedNCT02712905Phase 1/2Results posted
• Tremelimumab and Durvalumab With or Without Radiation Therapy in Patients With Relapsed Small Cell Lung CancerCompletedNCT02701400Phase 2Results posted
• Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung CancerCompletedNCT02674568Phase 2Results posted
• Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine TumorsActive, not recruitingNCT02589522Phase 1Results posted
• Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin Versus CAV or Topotecan as Treatment in Patients With Small-Cell Lung CancerCompletedNCT02566993Phase 3Results posted
• Pembrolizumab and Paclitaxel in Refractory Small Cell Lung CancerCompletedNCT02551432Phase 2Results posted
• An Investigational Immuno-therapy Study of Nivolumab, or Nivolumab in Combination With Ipilimumab, or Placebo in Patients With Extensive-Stage Disease Small Cell Lung Cancer (ED-SCLC) After Completion of Platinum-based ChemotherapyCompletedNCT02538666Phase 3Results posted
• Trilaciclib (G1T28) in Patients With Previously Treated Extensive Stage SCLC Receiving Topotecan ChemotherapyCompletedNCT02514447Phase 1/2Results posted
• Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Etoposide and Carboplatin in Extensive Stage Small Cell Lung Cancer (SCLC)CompletedNCT02499770Phase 1/2Results posted
• A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid TumorsActive, not recruitingNCT02498613Phase 2Results posted
• RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)CompletedNCT02489903Phase 2Results posted
• Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell CancersCompletedNCT02487095Phase 1/2Results posted
• Effectiveness Study of Nivolumab Compared to Chemotherapy in Patients With Relapsed Small-cell Lung CancerCompletedNCT02481830Phase 3Results posted
• Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung CancerCompletedNCT02394548Not applicableResults posted
• Alisertib (MLN8237) in Combination With Weekly Paclitaxel in East Asian Patients With Advanced Solid TumorsTerminatedNCT02367352Phase 1Results posted
• MK-3475 as Maintenance Therapy in Extensive Stage SCLCCompletedNCT02359019Phase 2Results posted
• A Global Study to Assess the Effects of MEDI4736 (Durvalumab), Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung CancerCompletedNCT02352948Phase 3Results posted
• Selinexor in Treating Patients With Relapsed Small Cell Lung CancerTerminatedNCT02351505Phase 2Results posted
• Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family CaregiversCompletedNCT02349412Phase 3Results posted
• Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast CancerCompletedNCT02312622Phase 2Results posted
• Dose Escalation and Double-blind Study of Veliparib in Combination With Carboplatin and Etoposide in Treatment-naive Extensive Stage Disease Small Cell Lung CancerCompletedNCT02289690Phase 1/2Results posted
• A Phase I/II Study of Ganetespib in Combination With DoxorubicinTerminatedNCT02261805Phase 1/2Results posted
• BMS-986012 in Relapsed/Refractory SCLCCompletedNCT02247349Phase 1/2Results posted
• Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects With Metastatic Small Cell Lung CancerCompletedNCT02200757Phase 2Results posted
• Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical CancerCompletedNCT02164461Phase 1Results posted
• Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without ChemotherapyTerminatedNCT02062632Phase 2Results posted
• Small Cell Lung Carcinoma Trial With Nivolumab and IpiliMUmab in LImited DiseaseCompletedNCT02046733Phase 2Results posted
• Phase 2 Study of Alisertib (MLN8237) in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel as Second Line Therapy for Small Cell Lung Cancer (SCLC)CompletedNCT02038647Phase 2Results posted
• Investigation of GSK2879552 in Subjects With Relapsed/Refractory Small Cell Lung CarcinomaTerminatedNCT02034123Phase 1Results posted
• Phase 1b/2 Study of Carfilzomib, Carboplatin, and Etoposide in Patients With Previously Untreated Extensive Stage Small-cell Lung CancerCompletedNCT01987232Phase 1/2Results posted
• Study Escalating Doses of PM01183 in Combination With Fixed Doxorubicin in Patients With Specific Advanced Unresectable Solid TumorsCompletedNCT01970540Phase 1Results posted
• Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer PatientsCompletedNCT01941316Phase 1/2Results posted
• Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive BiomarkersCompletedNCT01935336Phase 2Results posted
• Rovalpituzumab Tesirine (SC16LD6.5) in Recurrent Small Cell Lung CancerCompletedNCT01901653Phase 1/2Results posted
• Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung CancerCompletedNCT01880528Phase 2Results posted
• Pegylated Irinotecan NKTR 102 in Treating Patients With Relapsed Small Cell Lung CancerCompletedNCT01876446Phase 2Results posted
• A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Etoposide and Platinum TherapyTerminatedNCT01859741Phase 1/2Results posted
• Study of Pembrolizumab (MK-3475) Monotherapy in Advanced Solid Tumors and Pembrolizumab Combination Therapy in Advanced Non-small Cell Lung Cancer/ Extensive-disease Small Cell Lung Cancer (MK-3475-011/KEYNOTE-011)CompletedNCT01840579Phase 1Results posted
• Phase I Study of Lurbinectedin (PM01183) in Combination With Paclitaxel, With or Without Bevacizumab, in Selected Advanced Solid TumorsCompletedNCT01831089Phase 1Results posted
• Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung CancerTerminatedNCT01803269Phase 2Results posted
• Hippocampal Prophylactic Cranial Irradiation for Small Cell Lung CancerCompletedNCT01797159Not applicableResults posted
• Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung CancerCompletedNCT01737502Phase 1/2Results posted
• A Study of LY2940680 in Small Cell Lung CancerTerminatedNCT01722292Phase 1/2Results posted
• Phase 2a Desipramine in Small Cell Lung Cancer and Other High-Grade Neuroendocrine TumorsTerminatedNCT01719861Phase 2Results posted
• Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung CancerCompletedNCT01642251Phase 1/2Results posted
• Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung CancerActive, not recruitingNCT01638546Phase 2Results posted
• Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial CancerCompletedNCT01631552Phase 1/2Results posted
• Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the BrainCompletedNCT01553916Phase 1/2Results posted
• Effect of Chemotherapy With Paclitaxel/Cisplatin on Development Dysgeusia in Non Small Cell Lung CancerCompletedNCT01540045Results posted
• Linsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung CancerCompletedNCT01533181Phase 2Results posted
• Cabazitaxel With or Without Carboplatin in Treating Patients With Previously Treated Metastatic Castration-Resistant Prostate CancerCompletedNCT01505868Phase 1/2Results posted
• Cabazitaxel Compared to Topotecan for the Treatment of Small Cell Lung CancerCompletedNCT01500720Phase 2Results posted
• Bronchoscopic Intratumoral Chemotherapy for Small Cell Lung Cancer (SCLC)TerminatedNCT01487499Phase 3Results posted
• Study of Arsenic Trioxide in Small Cell Lung CancerCompletedNCT01470248Phase 2Results posted
• Trial in Extensive-Disease Small Cell Lung Cancer (ED-SCLC) Subjects Comparing Ipilimumab Plus Etoposide and Platinum Therapy to Etoposide and Platinum Therapy AloneCompletedNCT01450761Phase 3Results posted
• A Study of LY2510924 in Participants With Extensive-Stage Small Cell Lung CarcinomaCompletedNCT01439568Phase 2Results posted
• Early Palliative Care in Advanced Lung and Gastrointestinal MalignanciesCompletedNCT01401907Not applicableResults posted
• A Study to Evaluate Pazopanib in Comparison to Pemetrexed in Maintenance Setting in Non-progressing Subjects With Metastatic Stage IVA and IVB Non-squamous Non-small Cell Lung Cancer (NSCLC) PopulationTerminatedNCT01313663Phase 2Results posted
• Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic MalignanciesCompletedNCT01306045Phase 2Results posted
• Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid TumorsCompletedNCT01286987Phase 1Results posted
• To Determine Safe and Effective Dose of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Participants With Advanced Non-small Cell Lung CancerTerminatedNCT01284348Phase 2Results posted
• Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical CancerCompletedNCT01266447Phase 2Results posted

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