Small Cell Lung Carcinoma: all 1,234 studies

Page 4 of 13. Open to participants first (350), then studies with results posted, then the rest; newest registration first within each.

• Quantifying Systemic Immunosuppression to Personalize Cancer TherapyRecruitingNCT05621837
• Autologous CAR T-Cells Targeting the GD2 Antigen for Lung CancerRecruitingNCT05620342Early Phase 1
• Surufatinib Combined With Irinotecan as a Second-line Treatment for Small Cell Lung CancerNot yet recruitingNCT05595889Phase 2
• A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid TumorsRecruitingNCT05592626Phase 1/2
• Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver MetastasesRecruitingNCT05588388Phase 2
• Study of Trilaciclib and LurbinectidinRecruitingNCT05578326Phase 2
• A Safety Study of 212Pb-Pentixather Radioligand TherapyNot yet recruitingNCT05557708Early Phase 1
• Phase II Trial of Consolidative Thoracic Radiotherapy for ES-SCLC After Standard Care of Chemo-immunotherapyRecruitingNCT05552846Not applicable
• Study of Surufatinib Combined With Sintilimab and SCRT in Advanced Solid TumorsNot yet recruitingNCT05527821Phase 2
• The Efficiency of Surgery and Radiotherapy After SHR-1316 (Adebrelimab) and Platinum-containing Doublet Induction Therapy for Limited-stage Small Cell Lung CancerNot yet recruitingNCT05496166Phase 3
• JAB-2485 Activity in Adult Patients With Advanced Solid TumorsRecruitingNCT05490472Phase 1/2
• Durvalumab Combined With Consolidation Radiotherapy After First-line Treatment in Extensive Stage Small Cell Lung Cancer With OligometastasesNot yet recruitingNCT05484583Phase 2
• Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung CancerRecruitingNCT05450965Phase 2
• Consolidation Serplulimab Following Concurrent Chemoradiotherapy for LS-SCLC PatientsRecruitingNCT05443646Phase 2
• A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the BrainRecruitingNCT05419076Phase 2
• Phase 2 Study for the Patient, Who Has Diagnosed With Small Cell Lung Cancer (SCLC) or Non Small Cell Lung Cancer (NSCLC) or Renal Cell Carcinoma (RCC) and Finished the First Line Stand Treatment , Need More TreatmentRecruitingNCT05363280Phase 2
• Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With CancerRecruitingNCT05297734Not applicable
• Efficacy and Biomarker Explanation of IBI-322 Plus Lenvatinib on Extensive Stage Small Cell Lung CancerRecruitingNCT05296603Phase 2
• Chiauranib for Advanced Solid Malignant Tumors and Relapsed/Refractory SCLC.RecruitingNCT05271292Phase 1/2
• Biology of Young Lung Cancer Study: The YOUNG LUNG StudyRecruitingNCT05265429
• Tempus Small Cell Lung Cancer Observational Study (Sculptor)RecruitingNCT05257551
• A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Solid TumorRecruitingNCT05194982Phase 1
• Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)RecruitingNCT05068232Phase 2
• Application of ctDNA in the Evaluation of Curative Effect and Prognosis of SCLC PatientsNot yet recruitingNCT05066945
• Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung CancerRecruitingNCT04952480Phase 2
• JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung CancerRecruitingNCT04951947Phase 2
• Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung CancerRecruitingNCT04919382Phase 2
• Efficacy and Safety of Prophylactic Cranial Irradiation Versus MRI Surveillance in Patients With Limited-stage Small Cell Lung Cancer Who Achieved Remission After First-line ChemoradiotherapyRecruitingNCT04829708Phase 3
• PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)RecruitingNCT04790253Not applicable
• The Study is Being Conducted to Evaluate the Efficacy and Safety of SHR-1316 in Combination With Chemo-radiotherapy in Patients With LS-SCLC.Enrolling by invitationNCT04691063Phase 3
• The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)RecruitingNCT04585750Phase 1/2
• A Prospective Study Comparing Two Radiotherapy Dose/Fraction and Omitting CTVs of the Primary Tumor in Limited SCLCRecruitingNCT04543890Phase 2
• Pilot Study of PD-1inhibitor (Tislelizumab) Plus Chemotherapy as Neoadjuvant Therapy for Limited-Stage Small-Cell Lung CancerRecruitingNCT04542369Phase 2
• PD-L1 Antibody (TQB2450) Plus Chemotherapy for Previously Untreated Limited- Stage Small-cell Lung CancerRecruitingNCT04539977Phase 2
• A Multicenter Cancer Biospecimen Collection StudyRecruitingNCT04510129
• Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung CancerRecruitingNCT04342429Not applicable
• Study to Assess Safety,Tolerability,Efficacy of PM01183 and Atezolizumab in Patients w/ Advanced Small Cell Lung Cancer.RecruitingNCT04253145Phase 1/2
• PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56RecruitingNCT04199741Phase 1/2
• Talazoparib and Thoracic RT for ES-SCLCRecruitingNCT04170946Phase 1
• VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or LymphomaRecruitingNCT03556228Phase 1/2
• Clinical Study of Combined Radical Operation With Postoperative Adjuvant Chemotherapy and Prophylactic Cranial Irradiation in pT1-2N0M0 Stage of Small Cell Lung CancerRecruitingNCT03514849Not applicable
• Phase I Trial of CArbonic Anhydrase Inhibition in Combination With Radiochemotherapy or Radioimmunotherapy in Small Cell Lung CarcinomaRecruitingNCT03467360Phase 1
• A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular LymphomaRecruitingNCT03460977Phase 1
• Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid TumorRecruitingNCT03093688Phase 1/2
• Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma PatientsRecruitingNCT02622581
• Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial TumorsRecruitingNCT02146170
• Oral Green Tea Extract for Small Cell Lung CancerAvailableNCT01317953
• Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal VolunteersRecruitingNCT00900419
• DNA Analysis of Blood and Tissue From Patients With Lung CancerRecruitingNCT00471978
• Lung Cancer Biomarkers and ScreeningRecruitingNCT00301119
• MGC018 in Patients With Relapsed or Refractory Extensive-Stage Small-Cell Lung CancerActive, not recruitingNCT06227546Phase 2Results posted
• Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung CancerActive, not recruitingNCT05740566Phase 3Results posted
• A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid TumorsTerminatedNCT05551117Phase 2Results posted
• Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)Active, not recruitingNCT05224141Phase 3Results posted
• A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung CancerActive, not recruitingNCT05091567Phase 3Results posted
• Novel Optical Surface Image Guidance System for Beam-Gated Online Adaptive SBRT Delivery in Mobile Lower Lung and Upper Abdominal MalignanciesCompletedNCT05030454Not applicableResults posted
• Study of Ociperlimab Plus Tislelizumab Plus Chemoradiotherapy in Participants With Untreated Limited-Stage Small Cell Lung CancerCompletedNCT04952597Phase 2Results posted
• A Trial With Chemotherapy, Immunotherapy, and Radiotherapy for Patients With Newly Diagnosed Stage IV Small Cell Lung CancerTerminatedNCT04951115Phase 2Results posted
• Apalutamide Plus Cetrelimab in Patients With Treatment-Emergent Small Cell Neuroendocrine Prostate CancerTerminatedNCT04926181Phase 2Results posted
• Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99)CompletedNCT04924101Phase 2Results posted
• Liver Directed RT + Chemo-immunotherapy for ES-SCLCTerminatedNCT04923776Phase 2Results posted
• Phase 3 Study Evaluating Efficacy, Safety and Pharmacokinetics of Trilaciclib In Small Cell Lung Cancer PatientsCompletedNCT04902885Phase 3Results posted
• AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)CompletedNCT04885998Phase 1Results posted
• Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung CancerCompletedNCT04774380Phase 3Results posted
• Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)CompletedNCT04768296Phase 2Results posted
• Safety and Clinical Activity of Nivatrotamab in Relapsed/Recurrent Metastatic Small-cell Lung CancerTerminatedNCT04750239Phase 1/2Results posted
• Study of AZD2811 + Durvalumab in ES-SCLCActive, not recruitingNCT04745689Phase 2Results posted
• Durvalumab Plus Chemotherapy in Untreated Patients With Extensive-Stage Small Cell Lung CancerCompletedNCT04712903Phase 3Results posted
• A Study of BMS-986012 in Combination With Carboplatin, Etoposide, and Nivolumab as First-line Therapy in Extensive-stage Small Cell Lung CancerCompletedNCT04702880Phase 2Results posted
• Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung CancerCompletedNCT04665856Phase 3Results posted
• Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain MetastasesTerminatedNCT04610684Phase 2Results posted
• Safety and Efficacy of XmAb18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung CancerTerminatedNCT04590781Phase 1/2Results posted
• Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic RadiosurgeryTerminatedNCT04588246Phase 3Results posted
• Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid TumorsTerminatedNCT04579757Phase 1/2Results posted
• Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic CancerActive, not recruitingNCT04514497Phase 1Results posted
• Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIVActive, not recruitingNCT04514484Phase 1Results posted
• Durvalumab Plus Chemotherapy in ES-SCLC (Oriental)CompletedNCT04449861Phase 3Results posted
• A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).TerminatedNCT04422210Phase 1Results posted
• Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung CancerTerminatedNCT04373369Phase 2Results posted
• NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid TumorsCompletedNCT04332653Phase 1/2Results posted
• Trial of NanoPac Intratumoral Injection in Lung CancerCompletedNCT04314895Phase 2Results posted
• A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung CancerCompletedNCT04256421Phase 3Results posted
• Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid TumorsTerminatedNCT04234113Phase 1Results posted
• Resiliency Among Older Adults Receiving Lung Cancer TreatmentCompletedNCT04229381Not applicableResults posted
• PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell CancersCompletedNCT04209595Phase 1/2Results posted
• Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411TerminatedNCT04101357Phase 1/2Results posted
• Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine TumorsActive, not recruitingNCT04079712Phase 2Results posted
• A Phase III Study to Investigate Efficacy and Safety of HLX10 + Chemotherapy in Patients With ES-SCLCCompletedNCT04063163Phase 3Results posted
• A Study of Ladiratuzumab Vedotin in Advanced Solid TumorsTerminatedNCT04032704Phase 2Results posted
• Study of Platinum Plus Etoposide With or Without Tislelizumab in Participants With Untreated Extensive-Stage Small Cell Lung CancerCompletedNCT04005716Phase 3Results posted
• Tumor Treating Fields (TTFields) Therapy to Manage Brain Metastases in Small Cell Lung CancerTerminatedNCT03995667Phase 2Results posted
• Combination Rucaparib With Nivolumab in Small Cell Lung CarcinomaCompletedNCT03958045Phase 2Results posted
• Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung CancerCompletedNCT03913455Phase 2Results posted
• Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the LungsActive, not recruitingNCT03896503Phase 2Results posted
• Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced MalignanciesTerminatedNCT03881488Phase 1Results posted
• DS-3201b and Irinotecan for Patients With Recurrent Small Cell Lung CancerTerminatedNCT03879798Phase 1/2Results posted
• Evaluate the Safety, Tolerability, Biodistribution and Anti Tumour Activity of 177LU-OPS201 With Companion Imaging 68Ga-OPS202 PET/CT in Previously Treated Subjects With Locally Advanced or Metastatic Cancers Expressing Somatostatin Receptor 2 (SSTR2)TerminatedNCT03773133Phase 1/2Results posted
• Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced CancersCompletedNCT03761914Phase 1/2Results posted
• Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung CancerCompletedNCT03735095Phase 1/2Results posted
• [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)TerminatedNCT03724253Phase 2Results posted

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