Small Cell Lung Carcinoma: all 1,234 studies
Page 7 of 13. Open to participants first (350), then studies with results posted, then the rest; newest registration first within each.
- A Study to Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for SCLCCompletedNCT06478043Phase 2
- Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With ChemotherapyActive, not recruitingNCT06449209Phase 2
- An Investigational Scan (124I-hJAA-F11 PET/CT) for Diagnosing Lung CancerWithdrawnNCT06427369Phase 1
- A Study With NKT3447 for Adults With Advanced/Metastatic Solid TumorsTerminatedNCT06264921Phase 1
- A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage TumorsActive, not recruitingNCT06257264Phase 1
- PET-guided Radiotherapy for Patients With Small Cell Lung Cancer.CompletedNCT06247163
- Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and DurvalumabActive, not recruitingNCT06211036Phase 3
- Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung CancerTerminatedNCT06140407Phase 2
- Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)Active, not recruitingNCT06117774Phase 3
- DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung CancerActive, not recruitingNCT06077500Phase 1
- Tarlatamab (AMG 757) Expanded Access Protocol for Advanced Small Cell Lung CancerApproved for marketingNCT06064500
- ARTEMIS-007: HS-20093 in Patients With Extensive Stage Small Cell Lung CancerWithdrawnNCT06052423Phase 2
- Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)TerminatedNCT06022757Phase 1/2
- A Real-World Assessment of the Demographic, Clinical Characteristics and Outcomes of a Brazilian Cohort of Previously Untreated Extensive Stage-Small Cell Lung Cancer Receiving Durvalumab Combined With Platinum-Etoposide in (ES-SCLC) in BrazilActive, not recruitingNCT06008353
- DAREON™-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent ChemotherapyActive, not recruitingNCT05990738Phase 1
- Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After TreatmentActive, not recruitingNCT05957510Phase 2
- Molecular Subtyping of Extensive Stage Small Cell Lung Cancer and Relevent Clinical SignificanceCompletedNCT05933863
- A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Advanced Solid TumorsStatus unknownNCT05886075Early Phase 1
- A Study to Test How Well Different Doses of Obrixtamig (BI 764532) in Combination With Ezabenlimab Are Tolerated by People With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3Active, not recruitingNCT05879978Phase 1
- Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving TopotecanActive, not recruitingNCT05874401Phase 4
- Minimal Residual Disease Dynamic Monitoring in First-Line Serplulimab Plus Chemotherapy in Treatment of Extensive Small Cell Lung Cancer: An Observational StudyStatus unknownNCT05873790
- Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene AmplificationsTerminatedNCT05827614Phase 1
- Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based TherapyTerminatedNCT05815160Phase 1
- Chemotherapy and Immunotherapy in Extensive-Stage Small-Cell Lung Cancer With Thoracic RadiotherapyActive, not recruitingNCT05796089Phase 2
- Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor MalignanciesActive, not recruitingNCT05783622Phase 1
- Study of Low-Dose Radiotherapy Concurrent Chemotherapy With Serplulimab for Patients With ES-SCLCActive, not recruitingNCT05765825Phase 2
- Durvalumab in Combination With Standard Chemotherapy of Patients With Extensive Stage Small Cell Lung CancerActive, not recruitingNCT05761977
- HTMC0435 and Temozolomide in Treating Patients With Small Cell Lung CancerStatus unknownNCT05728619Phase 1/2
- Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving ImmunotherapyActive, not recruitingNCT05703269Not applicable
- A French Real-life Study: EvaluatioN of durvALumab Utilization and Effectiveness for First Line Extensive Stage Small Cell Lung Cancer.Active, not recruitingNCT05683977
- Development and Validation of Nomogram Predicting Survival in Chinese SCLC PatientsCompletedNCT05673798
- Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic CancerActive, not recruitingNCT05620134Phase 1/2
- A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of RO7616789 in Advanced Small Cell Lung Cancer and Other Neuroendocrine CarcinomasCompletedNCT05619744Phase 1
- Durvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease is Limited to the ThoraxActive, not recruitingNCT05617963Phase 2
- ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung CancersTerminatedNCT05616624Phase 1/2
- Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid TumorsActive, not recruitingNCT05599984Phase 1
- Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable CancersWithdrawnNCT05582031Phase 2
- Lurbinectedin Combined With Durvalumab in Pre-treated Patients With Extensive Stage Small-cell Lung CancerWithdrawnNCT05572476Phase 2
- A Phase 3, Controlled, Open-label, Global Randomized Study of RRx-001 With a Platinum Doublet or a Platinum Doublet in Small Cell Lung CancerActive, not recruitingNCT05566041Phase 3
- 89Zr-girentuximab for PET Imaging of CAIX Positive Solid TumorsTerminatedNCT05563272Phase 2
- Study of Oral MRT-2359 in Selected Cancer PatientsActive, not recruitingNCT05546268Phase 1/2
- Hypofraction Radiotherapy for Limited-Stage Small Cell Lung CancerCompletedNCT05523908Not applicable
- Surufatinib Plus Anti-PD-1/L1 as Maintenance Therapy in Extensive-Stage Small Cell Lung CancerCompletedNCT05509699Phase 2
- Study of DLL3-CAR-NK Cells in the Treatment of Extensive Stage Small Cell Lung CancerStatus unknownNCT05507593Phase 1
- A Study of AK104 in Combination With Chiauranib in Patients With Extensive Stage Small Cell Lung CancerCompletedNCT05505825Phase 1/2
- Immunological Variables Associated to ICI Toxicity in Cancer PatientsStatus unknownNCT05429866Phase 2
- Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NETTerminatedNCT05420636Phase 2
- EP0057 in Combination With Olaparib in Relapsed Advanced Gastric Cancer and Small Cell Lung CancerWithdrawnNCT05411679Phase 2
- Adaptive SBRT Plus Chemoimmunotherapy for ES-SCLCSuspendedNCT05403723Phase 1
- Mass Balance Study of [14C]ChiauranibCompletedNCT05371899Not applicable
- A Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy in Patients With Extensive Small Cell Lung CancerStatus unknownNCT05354700Phase 2
- Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung CancerActive, not recruitingNCT05353439Phase 1
- A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung CancerActive, not recruitingNCT05353257Phase 3
- A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare CancersSuspendedNCT05337735Phase 2
- A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in ChinaCompletedNCT05337163
- A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.CompletedNCT05329623Phase 1
- Pulmonary Rehabılıtatıon Wıth Non-Small Lung CancerStatus unknownNCT05320458Not applicable
- Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy in Extensive-Stage Small Cell Lung CancerCompletedNCT05309629Phase 2
- Testing a Cognitive Behavioral Model for Reducing Dyspnea in Patients With Lung CancerCompletedNCT05304793Not applicable
- Utidelone in Third-line and Above Treatment of Small Cell Lung CancerStatus unknownNCT05299255Phase 2
- RW Effectiveness of Lurbinectedin in Extensive Stage SCLCCompletedNCT05285033
- Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC)Active, not recruitingNCT05280470Phase 2
- DIAGNOSIS, TREATMENT AND OUTCOME OF LUNG CANCER PATIENTSActive, not recruitingNCT05254119
- To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid TumorsCompletedNCT05253053Phase 1/2
- An Open Label, Multicenter Phase 2 Study of Durvalumab (MEDI4736) + Olaparib as Maintenance Therapy in ChineseStatus unknownNCT05245994Phase 2
- A Study to Investigate the Efficacy and Safety of Tislelizumab Combined With Sitravatinib as Maintenance Therapy for ES-SCLCActive, not recruitingNCT05228496Phase 2
- Chemo-immunotherapy Plus Thoracic Radiotherapy in Extensive Stage Small-cell Lung CancerTerminatedNCT05223647Phase 3
- A Study of Oncolytic Virus Injection (RT-01) in Patients With Extensive-Stage Small Cell Lung CancerStatus unknownNCT05205421Phase 1
- A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid MalignanciesActive, not recruitingNCT05199272Phase 1/2
- Circulating EV Long RNA Profiles in SCLCStatus unknownNCT05191849Not applicable
- The Efficacy and Safety of Radiotherapy Plus Niraparib and Toripalimab in Patients With Recurrent Small Cell Lung CancerStatus unknownNCT05162196Phase 2
- Safety, Tolerability and Preliminary Efficacy of JK1201I in Patients With SCLCStatus unknownNCT05158491Phase 1/2
- Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)CompletedNCT05153239Phase 3
- Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLCActive, not recruitingNCT05092412Phase 2
- Evaluation of TRILACICLIB in Chinese Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC) for Chemotherapy-induced Myelosuppression, Antitumor Effects of Combination Regimens, and Safety in a Real-world StudyCompletedNCT05071703Phase 4
- A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC)Active, not recruitingNCT05060016Phase 2
- Tumor Microenvironment Surveillance on Simultaneous Liver Metastases Extensive Stage Small Cell Lung CancerCompletedNCT05055999
- Efficacy Biomarker Investigation on Extensive Stage Small Cell Lung CancerCompletedNCT05055947
- Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)TerminatedNCT05049863Phase 1
- Durvalumab With Chemotherapy Followed by Sequential Radiotherapy for Limited Stage Small Cell Lung CancerStatus unknownNCT05034133Phase 2
- KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung CancerTerminatedNCT05027867Phase 2
- Tislelizumab Combined With Anlotinib and 2-cycles Irinotecan as Second Line Treatment of SCLCStatus unknownNCT05027100Not applicable
- A Study of IBI110 in Combination With Sintilimab and Chemotherapy in Patients With Untreated Extensive-Stage Small Cell Lung CancerCompletedNCT05026593Phase 1
- Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, in Patients With Solid TumorsCompletedNCT05002868Phase 1
- Anlotinib Plus Penpulimab as Second-line Treatment for Patients With Small Cell Lung Cancer After Failure of Platinum-based ChemotherapyCompletedNCT05001971Phase 2
- Chemotherapy Combined With Camrelizumab and Apatinib in First-line Treatment of ES-SCLCStatus unknownNCT05001412Phase 1
- Surufatinib Combined With Chemotherapy Plus Toripalimab or Not in the Treatment of Small Cell Lung CancerStatus unknownNCT04996771Phase 1/2
- NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung CancerActive, not recruitingNCT04986670Not applicable
- To Evaluate the Efficacy of Durvalumab + Anlotinib in Terms of OS and PFS.Active, not recruitingNCT04985851Not applicable
- Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to DrugsWithdrawnNCT04985357
- Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st ChemotherapyStatus unknownNCT04985201Phase 2
- A Phase II Study of Sintilimab Combined With Anlotinib in Treatment of ED-SCLCStatus unknownNCT04967625Phase 2
- Prophylactic Cranial Irradiation in Extensive-stage Small Cell Lung CancerStatus unknownNCT04947774
- Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer SubjectsCompletedNCT04939662Phase 2
- Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)Active, not recruitingNCT04938817Phase 1/2
- Fluzopalil in Combination With Anlotinib for Extensive Small-cell Lung CancerStatus unknownNCT04933175Phase 2
- Atezolizumab Combined With Chemotherapy in Extensive Stage SCLCCompletedNCT04920981
- Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid TumorsCompletedNCT04902872Phase 1/2
- Camrelizumab Plus Apatinib as Maintenance Therapy in Extensive-stage Small-cell Lung CancerStatus unknownNCT04901754Phase 2
- To Assess the Effectiveness and Safety of Zepzelca in Adult Patients With Extensive Stage Small Cell Lung Cancer (SCLC)CompletedNCT04894591