Sickle Cell Trait clinical trials
The registry lists 41 studies for Sickle Cell Trait across more than 10 countries. 11 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-17.
Status
- Completed
- 20
- Recruiting
- 8
- Active, not recruiting
- 4
- Terminated
- 3
- Not yet recruiting
- 3
- Status unknown
- 2
Phase
- Phase 2
- 6
- Phase 3
- 5
- Phase 1
- 4
Where
- United States
- 30
- France
- 7
- Canada
- 6
- Lebanon
- 6
- Egypt
- 5
- Colombia
- 3
Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (3) · Forma Therapeutics, Inc. (2) · UConn Health (2) · Pfizer (2) · Columbia University (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Novartis Pharmaceuticals (2) · HemaQuest Pharmaceuticals Inc. (2)
Studies
Recruiting first, then most recently updated. Showing 41 of 41 — search for more.
- Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell DiseaseRecruitingNCT05904093Phase 11 country
- Blood Sampling for Research Related to Sickle Cell DiseaseRecruitingNCT005422301 country
- A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)RecruitingNCT06439082Phase 35 countries
- 131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)RecruitingNCT07015684Phase 11 country
- Sickle Cell Kidney BiorepositoryRecruitingNCT070641741 country
- The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in MartiniqueNot yet recruitingNCT07351435
- Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)RecruitingNCT060713771 country
- Transfusion Exchanges and Cognition in Sickle Cell DiseaseNot yet recruitingNCT071684471 country
- Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell TraitRecruitingNCT070835311 country
- A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCDRecruitingNCT04201210Phase 22 countries
- Study of a Deformability Parameter of Red Blood CellNot yet recruitingNCT05850156
- Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease PatientsActive, not recruitingNCT03814746Phase 321 countries
- Developing the Family Map: Looking at Communal CopingCompletedNCT016330211 country
- Sickle Cell Hemoglobinopathies and Bone HealthActive, not recruitingNCT023069931 country
- ERYthrocyte Morphology Using Flow Imaging on ImageSTREAM CytometerCompletedNCT052828881 country
- Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell TraitCompletedNCT043491891 country
- Siplizumab for Sickle Cell Disease TransplantTerminatedNCT06078696Phase 1/21 country
- A Study to Learn About Sickle Cell Disease In Adult PatientsCompletedNCT054078051 country
- A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)Active, not recruitingNCT04624659Phase 317 countries
- The Sequestration of Holistic Stress Management Techniques for AdultsWithdrawnNCT06098755Not applicable1 country
- CHOICES3: Sickle Cell Disease Parenting CHOICESActive, not recruitingNCT05292781Not applicable1 country
- Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell DiseaseCompletedNCT000125451 country
- Increasing Documentation and Disclosure of Sickle Cell Trait Status: An Implementation Science ApproachCompletedNCT05387564Not applicable1 country
- A Study of Etavopivat in Patients With Thalassemia or Sickle Cell DiseaseCompletedNCT04987489Phase 26 countries
- A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive CrisesCompletedNCT04935879Phase 312 countries
- Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease.CompletedNCT042442401 country
- Effect of Exercise on Biomarkers in SCTCompletedNCT04273022Not applicable1 country
- Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and CanadaCompletedNCT05506358Not applicable2 countries
- At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic ConditionsCompletedNCT019316441 country
- A Program to Increase Sickle Cell Trait Knowledge Among Parent of Young Children Identified in Newborn ScreeningCompletedNCT03984500Not applicable1 country
- Evaluation of a Training Program for Homozygous Sickle Cell Disease PatientsCompletedNCT02571088Not applicable1 country
- Transfusion in Sickle Cell Disease: Screening of Sickle Cell Disease Trait in Blood DonorsCompletedNCT03405688Not applicable1 country
- Sickle Cell Trait and the Risk of Venous ThromboembolismTerminatedNCT011489401 country
- Sickle Cell Trait and Exercise, Effect of Hot EnvironmentCompletedNCT04028791Not applicable1 country
- Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ ChallengeCompletedNCT02237586Phase 11 country
- Effects of HQK-1001 in Patients With Sickle Cell DiseaseTerminatedNCT01601340Phase 25 countries
- Sickle Cell Trait in Football PlayersStatus unknownNCT018918771 country
- A Study of HQK-1001 in Patients With Sickle Cell DiseaseCompletedNCT01322269Phase 25 countries
- A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD)Status unknownNCT01202812Phase 21 country
- Diabetic Retinopathy and Sickle TraitCompletedNCT007203171 country
- Mobilization and Handling of Stem Cells for Transplant From Healthy Volunteers With Sickle Cell TraitCompletedNCT00005782Phase 31 country