Schizophrenia, Treatment-Resistant: all 53 studies

Page 1 of 1. Open to participants first (22), then studies with results posted, then the rest; newest registration first within each.

• Sequential Treatment Approaches for Treatment-Resistant SchizophreniaRecruitingNCT07918222Phase 3
• Effects of Nitraria Retusa Infusion on Clozapine-induced Metabolic Side EffectsRecruitingNCT07817069Not applicable
• Efficacy and Safety of Temporal Interference Stimulation in Treatment-Resistant Schizophrenia: An Exploratory Study.Not yet recruitingNCT07773831Not applicable
• Effectiveness of Exercise Alone and tDCS+Exercise on Cognitive Function Improvement in Patients With Treatment Resistant SchizophreniaNot yet recruitingNCT07404319Not applicable
• Deep Brain Stimulation of the Nucleus Accumbens and Anterior Limb of the Internal Capsule in the Treatment of Refractory SchizophreniaNot yet recruitingNCT07369401Not applicable
• Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant SchizophreniaRecruitingNCT07184619Phase 3
• Cognitive Behavioral Therapy for Sleep and Circadian Disturbances (CBT-I) in Treatment-Resistant SchizophreniaRecruitingNCT06749444Not applicable
• Magnetic Seizure Therapy for Schizophrenia - TrialRecruitingNCT06672588Not applicable
• Effect of Atenolol Versus Ivabradine on HRV in TRS Patients on Clozapine With Tachycardia: A Randomised Control Trial.RecruitingNCT06505668Not applicable
• Maintenance ElectroConvulsive Therapy in Clozapine RESISTant Schizophrenia - the MECT-RESIST TrialRecruitingNCT06456983Not applicable
• Reduction of Auditory-Verbal Hallucinations in Schizophrenia Through Cortical NeuromodulationRecruitingNCT06361160Not applicable
• Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium BenzoateRecruitingNCT06340789Phase 2
• The Role of Glutamatergic Function in the Pathophysiology of Treatment-resistant SchizophreniaRecruitingNCT06270108Early Phase 1
• Deep Brain Stimulation for PsychosisRecruitingNCT06257056Not applicable
• The Characteristics of Treatment Resistant Schizophrenia From the Illness OnsetNot yet recruitingNCT06128408
• Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology AnalysisNot yet recruitingNCT06060886Phase 4
• Add-on Aripiprazole on Cardiometabolic Profile in Treatment Resistant Schizophrenia: RCTNot yet recruitingNCT05766540Phase 4
• Hippocampus DBS in Treatment-resistant SchizophreniaRecruitingNCT05694000Not applicable
• Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory HallucinationsRecruitingNCT05299749Not applicable
• Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study.RecruitingNCT05074732
• Comparaison of Avatar Therapy to Cognitive Behavioral Therapy in Schizophrenia With Treatment Refractory HallucinationsRecruitingNCT04054778Not applicable
• An Adaptive Phase II/III, Two-Part, Double-Blind, Randomized, Placebo-controlled, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen®, as an Add-on Therapy With Clozapine, for Residual Symptoms of Refractory Schizophrenia in AdultsRecruitingNCT03094429Phase 2/3
• The Effectiveness and Efficacy of the Combination of the Integrated Psychological Therapy and Metacognitive Training.CompletedNCT05623228Phase 2Results posted
• Rituximab for Schizophrenia Spectrum Disorder (RITS-PS-2019)CompletedNCT03983018Phase 2Results posted
• Telmisartan Pilot Study on Treatment Resistant SchizophreniaTerminatedNCT03868839Phase 2Results posted
• Efficacy of Lu AF35700 in Patients With Early-in-disease or Late-in-disease Treatment-resistant SchizophreniaTerminatedNCT03230864Phase 3Results posted
• Time Course of Clozapine-associated Agranulocytosis Over 19 YearsCompletedNCT07913529
• Τhe Combination of Pharmacotherapy With RECOVERYTRSGR and RECOVERYTRSBDGR.Active, not recruitingNCT07047651Phase 4
• An Open-Label, Single-Arm Clinical Trial Evaluating the Safety and Efficacy of Amisulpride in Treating Patients With Schizophrenia and Schizoaffective Disorder Who Have Treatment-Resistant Positive SymptomsWithdrawnNCT05956600Not applicable
• Dextromethorphan as an Augmentation Agent in Treatment-resistant SchizophreniaCompletedNCT05944510Phase 4
• An Exploratory Analysis of Immune and Inflammatory Response Associated With ClozapineTerminatedNCT05741502Phase 4
• Deep Brain Stimulation Recovery in Treatment-Resistant SchizophreniaActive, not recruitingNCT05337904Not applicable
• Low-Intensity Focused Ultrasound Neuromodulation of the Mediodorsal Thalamus for Treatment-Resistant SchizophreniaSuspendedNCT05259306Not applicable
• Exploration of the Deep Transcranial Magnetic Stimulation for Treatment Resistant SchizophreniaStatus unknownNCT05167942Not applicable
• SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant SchizophreniaStatus unknownNCT04528095Phase 3
• Efficacy of tDCS in the Treatment of Resistant Auditory Hallucinations in SchizophreniaCompletedNCT04352569Not applicable
• The Synergistic Effect of Hypoglycemic Index Diet on Refractory SchizophreniaStatus unknownNCT04302636Not applicable
• Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant SchizophreniaCompletedNCT03807882Phase 4
• Avatar Therapy in Comparison to Cognitive Behavioral Therapy for Treatment-resistant SchizophreniaCompletedNCT03585127Not applicable
• Virtual Reality Therapy for Treatment-resistant Auditory Hallucinations in SchizophreniaCompletedNCT03148639Not applicable
• Neural Biomarkers of Clozapine ResponseCompletedNCT03076346
• Clozapine-induced Hypersalivation - Feasibility TrialCompletedNCT02613494Phase 1/2
• Deep Brain Stimulation in Treatment Resistant SchizophreniaCompletedNCT02377505Not applicable
• Deep Brain Stimulation in Treatment Resistant SchizophreniaTerminatedNCT02361554Not applicable
• Electroconvulsive Therapy (ECT) in Patients With Super Refractory SchizophreniaStatus unknownNCT02049021Phase 4
• Electroconvulsive Therapy for Treatment Refractory Schizophrenia - A Randomized, Double-blinded, Sham-controlled StudyTerminatedNCT01948999Not applicable
• Occupational Therapy in the Rehabilitation of Executive Functions in Patients With SchizophreniaStatus unknownNCT01879956Not applicable
• Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive DisorderCompletedNCT01596608Not applicable
• Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of CareCompletedNCT01431326
• Repetitive Transcranial Magnetic Stimulation for Refractory Auditory Hallucinations in SchizophreniaCompletedNCT01386918Not applicable
• Amisulpride Augmentation Therapy for Clozapine-resistant Schizophrenic PatientsCompletedNCT01105481Phase 4
• A Pilot Double-blind Sham-controlled Trial of Repetitive Transcranial Magnetic Stimulation for Patients With Refractory Schizophrenia Treated With ClozapineCompletedNCT01015001Phase 3
• FazaClo Outcomes in the Control of Schizophrenia (FOCUS) Study SurveyCompletedNCT00683891

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