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Schizophrenia Spectrum and Other Psychotic Disorders clinical trials

The registry lists 84 studies for Schizophrenia Spectrum and Other Psychotic Disorders across more than 10 countries. 14 are recruiting or about to start. 26 of them are mainly about Schizophrenia Spectrum and Other Psychotic Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 5 narrower conditions too, such as Schizophrenia: 4,163 studies, 636 open.

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Status

Completed
52
Recruiting
11
Status unknown
10
Terminated
4
Active, not recruiting
2
Not yet recruiting
2

Phase

Phase 2
16
Phase 4
5
Phase 1
5
Early Phase 1
3
Phase 3
2

Where

United States
32
Canada
9
Spain
9
Germany
6
Bulgaria
5
Hong Kong
4

Who runs them

Centre for Addiction and Mental Health (4) · University of Minnesota (4) · Fundación Marques de Valdecilla (3) · AbbVie (3) · Massachusetts General Hospital (2) · Karolinska Institutet (2) · National Institute on Drug Abuse (NIDA) (2) · Chinese University of Hong Kong (2)

Who develops what

Save this set

Every programme with a company-led study here in the last two years, whatever its size: 1 programme from 1 company, 0 with this as their studies’ main aim; 0 with a live phase 3 study; 0 primary completions in the next 12 months.

Comparator & background therapies

What other companies’ phase 2+ studies give as the comparator or the background here (its leading trial sponsor and partners left out): a sign of what new drugs are measured against, not by itself the standard of care, its prescriptions or its market.

None given by two companies or more yet.

Programmes

“Meets, by arms” reads each study’s arms: vs its arm against the therapy’s; + X vs a combination against it; added to it plus the therapy against the therapy; studied with given together only. The next primary completion is the next phase-3 study’s when there is one.

The 1 programme — sign in to see the whole list, free: filter by phase and aim, sort by late development, direct comparisons or the next primary completion.

Primary completion in the next 12 months (0)

Live phase 2 and 3 studies of these programmes. Primary completion is when the main measure’s data collection ends, as the registry states it (most are estimates); results come later, if they are announced.

None in the next 12 months.

Read from ClinicalTrials.gov, industry-led studies. Main aim: this is the study’s judged main condition; named, not the main aim: the sponsor names it, the study is about something else; registry mapping only: only the registry’s mapping put it here. Leading trial sponsor is the company leading the most industry studies of a drug, a measure of trial activity, not of rights. US and EU rights, and Approved: from the regulators’ records (FDA’s Drugs@FDA via openFDA; EMA’s medicines data) — the holder of a marketed or authorised original, generics and other companies’ versions; not rights elsewhere, nor approval for this condition. Phase 4 trial recorded, where neither lists it: a phase 4 study exists somewhere. Not read yet: labels by indication, exclusivity, licences, line of therapy, academic comparators, sales.

What is being tested here

Drugs under test in Schizophrenia Spectrum and Other Psychotic Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
ML-007C202
Tirzepatide101
Emraclidine003
Rituximab002
Risperidone002
Paliperidone002
Ziprasidone002
Cycloserine002
MK-8189001
Vitamin D001

Drug classes tested here Antipsychotics 5

Coming up

0phase 3 studies under way
6studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 6

Who these studies take

Of the 11 Schizophrenia Spectrum and Other Psychotic Disorders studies recruiting now, 7 (64%) set no upper age limit and 3 (27%) stop at 75 or younger. 1 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (18%) take healthy volunteers.

Recruiting studies that take each age, of 11
AgeWomenMen
101 (9%)1 (9%)
1810 (91%)10 (91%)
3010 (91%)10 (91%)
4010 (91%)10 (91%)
508 (73%)8 (73%)
659 (82%)9 (82%)
758 (73%)8 (73%)
858 (73%)8 (73%)

Across all 84 studies, recruiting or not: 70% stop at 75 or younger and 67% at 65; 23% take children; 0% are for women only and 1% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Schizophrenia Spectrum and Other Psychotic Disorders studies take

Of 27 interventional studies with no phase under Schizophrenia Spectrum and Other Psychotic Disorders, half reached primary completion within 41 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase41 mo26–59 · 27 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 84. Browse all 84 → or search them.