Affective Disorders, Psychotic clinical trials
The registry lists 26 studies for Affective Disorders, Psychotic across more than 10 countries. 3 are recruiting or about to start. 5 of them are mainly about Affective Disorders, Psychotic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Who runs them
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (5) · VA Office of Research and Development (3) · Centre for Addiction and Mental Health (2) · University of Minnesota (2) · Søren Dinesen Østergaard (1) · University Hospital, Akershus (1) · Universita di Verona (1) · US Department of Veterans Affairs (1)
What is being tested here
Drugs under test in Affective Disorders, Psychotic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Paliperidone | 0 | 3 | 3 |
| Topiramate | 0 | 2 | 2 |
| Ziprasidone | 0 | 0 | 1 |
| Mifepristone | 0 | 1 | 1 |
| Brexpiprazole | 0 | 1 | 1 |
Drug classes tested here Antipsychotics 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Apr 2027MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMI · VA Office of Research and Development
- Sep 2027SloMo2: Implementation, Effectiveness, and Cost-effectiveness Study · King's College London
Who these studies take
Of the 3 Affective Disorders, Psychotic studies recruiting now, 2 (67%) set no upper age limit and 1 (33%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 3 (100%) | 3 (100%) |
| 30 | 3 (100%) | 3 (100%) |
| 40 | 3 (100%) | 3 (100%) |
| 50 | 3 (100%) | 3 (100%) |
| 65 | 3 (100%) | 3 (100%) |
| 75 | 2 (67%) | 2 (67%) |
| 85 | 2 (67%) | 2 (67%) |
Across all 26 studies, recruiting or not: 62% stop at 75 or younger and 58% at 65; 23% take children; 0% are for women only and 0% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Results posted1
- Assessment and Treatment for Chronic Pain in Veterans With Serious Mental IllnessOct 29, 2026NCT04118283
Studies
Recruiting first, then most recently updated. Showing 26 of 26. search them.
- MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMIRecruitingNCT06138054Not applicable1 country
- SloMo2: Implementation, Effectiveness, and Cost-effectiveness StudyRecruitingNCT06568081Not applicable1 country
- CBT-CP for Veterans With SMIRecruitingNCT06758414Not applicable1 country
- Assessment and Treatment for Chronic Pain in Veterans With Serious Mental IllnessCompletedNCT04118283Not applicable1 country
- Early Psychosis Intervention - Spreading Evidence-based TreatmentCompletedNCT03919760Not applicable1 country
- ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis InterventionCompletedNCT04298450Not applicable1 country
- Arts-based Social Prescribing for Mental HealthCompletedNCT07137572Not applicable1 country
- Remote State Representation in Early PsychosisCompletedNCT05538832Early Phase 11 country
- Context-Aware Mobile Intervention for Social Recovery in Serious Mental IllnessCompletedNCT05660070Not applicable1 country
- Cognitive Training Delivered Remotely to Individuals With Psychosis (ROAM)CompletedNCT02782442Not applicable1 country
- Self-Management and Recovery Technology Psychosocial Intervention TrialCompletedNCT02474524Not applicable1 country
- Anomalous Self-Experience in First Episode Psychosis - A Six-Year Follow-Up StudyCompletedNCT023219431 country
- Treatment of Psychotic Major Depression With MifepristoneTerminatedNCT00867360Phase 31 country
- Brexpiprazole (OPC 34712) Trial in the Treatment of Adults With Major Depressive Disorder and IrritabilityWithdrawnNCT02212613Phase 31 country
- Implementation of Illness Management and Recovery in Mental Health ServicesCompletedNCT02077829Not applicable1 country
- Clinical Validation of the Rating Scale for Psychotic Depression (RAS-PD)CompletedNCT015180491 country
- Smoking Cessation for Veterans With Severe and Persistent Mental IllnessCompletedNCT00960375Phase 2/31 country
- Web-Based Weight Management for Individuals With Mental IllnessCompletedNCT01324973Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I DisorderCompletedNCT00309699Phase 38 countries
- A Large Pragmatic Cluster Randomized Controlled Trial of a Multi-element Psychosocial Intervention for Early PsychosisCompletedNCT01436331Not applicable1 country
- A Study to Evaluate the Safety and Effectiveness of Topiramate Compared to Placebo in the Treatment of Patients With Bipolar I DisorderCompletedNCT00035802Phase 3
- A Study to Evaluate the Efficacy and Safety of Three Fixed Doses of Extended-release Paliperidone in Subjects With Bipolar I DisorderCompletedNCT00299715Phase 3
- A Study of the Effectiveness and Safety of Topiramate in the Treatment of Patients With Bipolar DisorderCompletedNCT00240721Phase 3
- A Study to Evaluate the Efficacy and Safety of Adjustable Doses of Extended-release (ER) Paliperidone Compared With Placebo, in Combination With Lithium or Valproate, to Treat Manic and Mixed Episodes in Patients With Bipolar I DisorderCompletedNCT00309686Phase 3
- Safety And Efficacy Study Of Ziprasidone In Pediatric Psychotic IllnessCompletedNCT00199940Phase 4
- Routine Plasma Level Determination to Compare Actual vs Expected Plasma Levels at Psychiatric Inpatient AdmissionCompletedNCT006275101 country