Retinitis Pigmentosa: all 273 studies

Page 1 of 3. Open to participants first (71), then studies with results posted, then the rest; newest registration first within each.

• Natural History Study of Advanced RCDRecruitingNCT07854899Not applicable
• Phase I/II Open-Label Trial of UGX202 for Advanced Retinitis PigmentosaNot yet recruitingNCT07847723Phase 1
• Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Gene Therapy (SPVN20) in Subjects With Rod-Cone DystrophyRecruitingNCT07807111Phase 1/2
• Study to Evaluate the Long-Term Safety of Ultevursen in Participants With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A GeneNot yet recruitingNCT07796646Phase 2
• Safety Evaluation Study of Pitavastatin PLGA Nano-particle for Retinitis PigmentosaRecruitingNCT07774975Phase 1
• A 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher SyndromeRecruitingNCT07710196Phase 3
• Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual PerformanceRecruitingNCT07548944
• 9-cis Beta-Carotene-Rich Extract of Dunaliella Alga in Retinitis Pigmentosa PatientsEnrolling by invitationNCT07509229Phase 1/2
• Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)RecruitingNCT07502664
• A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)RecruitingNCT07408232Phase 1/2
• Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision ImpairmentRecruitingNCT07341763Not applicable
• UGX202 Injection in Patients With Advanced Retinitis PigmentosaNot yet recruitingNCT07311863Early Phase 1
• Wide Field OCTA in Ocular DiseasesNot yet recruitingNCT07298174
• Implementation and Evaluation of a Post-Diagnostic Announcement Protocol at the CRMR RefeRet, Quinze-Vingts HospitalRecruitingNCT07292987Not applicable
• 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher SyndromeNot yet recruitingNCT07290530Phase 3
• Prospective, Randomized, Sham-controlled, Dose-finding I/II Trial of Safety and Efficacy of Modified Optogenetic Gene Therapy (ZM-02 Injection)Not yet recruitingNCT07282457Phase 1/2
• Restoration of Central Vision With PRIMA in Patients With Photoreceptor DegenerationRecruitingNCT07266584Not applicable
• Inherited Retinal Diseases: Natural History and Genotype-Phenotype CorrelationsNot yet recruitingNCT07265895
• Natural History Study of Patients With EYS-Associated RPRecruitingNCT07228793
• Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract PatientsRecruitingNCT07126470Not applicable
• Subthreshold Micropulse Laser Therapy (SML) in Retinitis PigmentosaEnrolling by invitationNCT07088705Not applicable
• A Multicenter, Randomized, Double-Blind, Controlled Clinical Study of Minocycline for the Treatment of Retinitis PigmentosaNot yet recruitingNCT07082855Phase 3
• Prospective Exploratory Cohort Study on Ganglion Cell Degeneration in Retinitis Pigmentosa PatientsEnrolling by invitationNCT07056738
• InsightRP2 RegistryRecruitingNCT06982417
• Safety and Efficacy of ZVS203e in the Treatment of Retinitis Pigmentosa Caused by RHO Gene MutationRecruitingNCT06952842Phase 1/2
• An Open-label, Dose-ascending Study of IGT001 for Retinitis PigmentosaRecruitingNCT06936787Phase 1
• Functional Assessments in Vision ImpairmentNot yet recruitingNCT06908161
• A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis PigmentosaRecruitingNCT06891885Phase 1/2
• Retinal Investigation Using Optos OCT DeviceNot yet recruitingNCT06846151Not applicable
• A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)RecruitingNCT06789445Phase 1/2
• Evaluating a New Peptide Therapy for Retinal Diseases: AMD, Diabetic Retinopathy, and DystrophiesRecruitingNCT06787482Phase 1/2
• A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis PigmentosaRecruitingNCT06628947Phase 2
• Study of Subretinally Injected AAVB-081 in Patients With Usher Syndrome Type IB (USH1B) Retinitis PigmentosaRecruitingNCT06591793Phase 1/2
• A New Diagnostic Paradigm for Retinitis Pigmentosa Secondary to USH2A Pathogenic VariantsNot yet recruitingNCT06545253
• Gene Therapy for RPGR Gene Mutation-associated X-linked Retinitis PigmentosaRecruitingNCT06492850Phase 1/2
• Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal DegenerationRecruitingNCT06375239
• The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal DegenerationRecruitingNCT06319872Phase 1
• Biomarkers in Retinitis PigmentosaRecruitingNCT06306690
• Safety and Efficacy Study of Novel Gene Therapy ZM-02 for Retinitis Pigmentosa PatientsRecruitingNCT06292650Early Phase 1
• Safety and Tolerability of Intravitreal Administration of VG901 in Patients With Retinitis Pigmentosa Due to Mutations in the CNGA1 GeneRecruitingNCT06291935Phase 1
• A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)Enrolling by invitationNCT06275620Phase 2
• Safety and Efficacy of Stem Cell Small Extracellular Vesicles in Patients With Retinitis PigmentosaRecruitingNCT06242379Phase 1/2
• Coloured-light in Retinitis Pigmentosa.Not yet recruitingNCT06224114Not applicable
• Evaluation of New Head-mounted Visual Aids Among Patients With Low VisionNot yet recruitingNCT06076720Not applicable
• A Long-Term Follow-Up Study in Subjects Who Received vMCO-I Administered Via Intravitreal InjectionEnrolling by invitationNCT05921162
• Non-invasive Ultrasound Retinal Stimulation for Vision RestorationNot yet recruitingNCT05914233Not applicable
• Role of UC-MSC and CM to Inhibit Vision Loss in Retinitis Pigmentosa Phase I/IINot yet recruitingNCT05909488Phase 2/3
• Gene Therapy for Subjects With RPGR Mutation-associated X-linked Retinitis PigmentosaRecruitingNCT05874310Early Phase 1
• Pilot Study of AuTNA IRecruitingNCT05853107Not applicable
• Study of BEST1 Vitelliform Macular DystrophyRecruitingNCT05809635
• Safety and Tolerability Study of Gene Editing Drug ZVS203e in Participants With Retinitis PigmentosaRecruitingNCT05805007Early Phase 1
• Long-term Safety of UC-MSC Transplantation in Patients With Retinitis PigmentosaNot yet recruitingNCT05786287
• Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic VariantsRecruitingNCT05589714
• Adaptive Optics Imaging of Outer Retinal DiseasesRecruitingNCT05355415
• Structural and Functional Characterization of Rare Ocular DiseasesRecruitingNCT05258032
• Longitudinal Study of a Bionic EyeEnrolling by invitationNCT05158049
• Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAIONRecruitingNCT05147701Phase 1
• BS01 in Patients With Retinitis PigmentosaRecruitingNCT04278131Phase 1/2
• High Resolution, High-speed Multimodal Ophthalmic ImagingRecruitingNCT04129021Not applicable
• Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.RecruitingNCT03990727
• Stem Cell Ophthalmology Treatment Study IIRecruitingNCT03011541Not applicable
• Clinical Implication of Retinitis Pigmentosa Molecular Diagnostic Using High Throughput Sequencing.RecruitingNCT02860520
• Rod and Cone Mediated Function in Retinal DiseaseRecruitingNCT02617966
• Clinical Trials of Continuous Oxygen Therapy Combined With Blue Light Deprivation in the Treatment of Retinitis PigmentosaNot yet recruitingNCT02465749Early Phase 1
• Inherited Retinal Degenerative Disease RegistryRecruitingNCT02435940
• The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions in Adolescent Patients With Retinitis PigmentosaNot yet recruitingNCT02018692Phase 1/2
• Evaluation of Objective Perimetry Using Chromatic Multifocal PupillometerRecruitingNCT02014389
• High Resolution Retinal ImagingRecruitingNCT01866371
• Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168
• Cell Collection to Study Eye DiseasesRecruitingNCT01432847
• Retinal Imaging in Patients With Inherited Retinal DegenerationsRecruitingNCT00254605
• A Study in Subjects With Retinitis PigmentosaCompletedNCT05392179Phase 2Results posted
• The Perceptual Experience of Argus II UsersCompletedNCT05285618Not applicableResults posted
• Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)TerminatedNCT05176717Phase 2/3Results posted
• Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)TerminatedNCT05158296Phase 2/3Results posted
• An Open-Label Extension Study to Evaluate Safety & Tolerability of QR-421a in Subjects With Retinitis PigmentosaTerminatedNCT05085964Phase 2Results posted
• Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis PigmentosaCompletedNCT04604899Phase 2Results posted
• Environmental Localization Mapping and Guidance for Visual Prosthesis UsersCompletedNCT04359108Not applicableResults posted
• Sildenafil for Treatment of Choroidal IschemiaCompletedNCT04356716Phase 2Results posted
• Object Finder for a Retinal ProsthesisCompletedNCT04319809Not applicableResults posted
• Advancing Understanding of Transportation OptionsCompletedNCT04141891Not applicableResults posted
• Computer-Assisted Rehabilitation Environment Training After Argus Retinal ProsthesisCompletedNCT03444961Not applicableResults posted
• Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP)CompletedNCT03322930Results posted
• Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) - Retinitis Pigmentosa GTPase Regulator (RPGR)CompletedNCT03252847Phase 1/2Results posted
• A Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using BIIB112CompletedNCT03116113Phase 1/2Results posted
• Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells in Adults With Retinitis PigmentosaCompletedNCT03073733Phase 2Results posted
• Collision Warning Device for Blind and Visually ImpairedCompletedNCT03057496Not applicableResults posted
• Visual Activity Evoked by Infrared in Humans After Dark AdaptationCompletedNCT02909985Not applicableResults posted
• Aflibercept for Macular Oedema With Underlying Retinitis Pigmentosa (AMOUR) StudyCompletedNCT02661711Phase 2Results posted
• AGN-151597 (Formerly RST-001) Phase I/II Trial for Advanced Retinitis PigmentosaCompletedNCT02556736Phase 1/2Results posted
• Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis PigmentosaCompletedNCT02320812Phase 1/2Results posted
• Cone Rescue in Retinitis Pigmentosa by the Treatment of Lycium BarbarumCompletedNCT02244996Not applicableResults posted
• Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis PigmentosaCompletedNCT02140164Phase 1/2Results posted
• A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP)CompletedNCT02110225Phase 1/2Results posted
• Transcorneal Electrostimulation for Therapy of Retinitis PigmentosaCompletedNCT01837901Not applicableResults posted
• Retinal Imaging in CNTF -Releasing Encapsulated Cell Implant Treated Patients for Early-stage Retinitis PigmentosaCompletedNCT01530659Phase 2Results posted
• Study of SAR421869 in Participants With Retinitis Pigmentosa Associated With Usher Syndrome Type 1BTerminatedNCT01505062Phase 1/2Results posted
• Trial of Subretinal Injection of (rAAV2-VMD2-hMERTK)CompletedNCT01482195Phase 1Results posted
• Evoked Retinal ResponseTerminatedNCT01415453Not applicableResults posted
• Trial of Oral Valproic Acid for Retinitis PigmentosaCompletedNCT01233609Phase 2Results posted

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