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RecruitingNCT02435940MRTRUpdated May 19, 2026

Inherited Retinal Degenerative Disease Registry

An observational study in Eye Diseases Hereditary, Retinal Disease and Achromatopsia, sponsored by Foundation Fighting Blindness. Recruiting at 1 site in United States. Per ClinicalTrials.gov, last updated 2026-05-19.

Sponsored by Foundation Fighting Blindness · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
20,000
Sex
All
01

Study summary

The My Retina Tracker® Registry is sponsored by the Foundation Fighting Blindness and is for people affected by one of the rare inherited retinal degenerative diseases studied by the Foundation. It is a patient-initiated registry accessible via a secure on-line portal at www.MyRetinaTracker.org. Affected individuals who register are guided to create a profile that captures their perspective on their retinal disease and its progress; family history; genetic testing results; preventive measures; general health and interest in participation in research studies. The participants may also choose to ask their clinician to add clinical measurements and results at each clinical visit. Participants are urged to update the information regularly to create longitudinal records of their disease, from their own perspective, and their clinical progress. The overall goals of the Registry are: to better understand the diversity within the inherited retinal degenerative diseases; to understand the prevalence of the different diseases and gene variants; to assist in the establishment of genotype-phenotype relationships; to help understand the natural history of the diseases; to help accelerate research and development of clinical trials for treatments; and to provide a tool to investigators that can assist with recruitment for research studies and clinical trials.

Read the detailed description

My Retina Tracker Registry provides two portals for data entry and review. Initial registration in the My Retina Tracker Registry is initiated by a participant, not a clinician. Using the participant portal, the participant establishes a username and password, is guided through on-line informed consent, and can then use an interactive guide to record their ophthalmic and family history, genotype and other subjective diagnosis-related and general health information. Drop-down menus and standardized vocabulary are used for database consistency. They may also attach documents, such as medical records, to maintain their personal medical files on their disease. Participants are encouraged to update their profiles regularly to create a longitudinal history of their disease. Participants can see aggregated data for all other participants in the registry and compare their own disease and status to others.

After a profile has been established, Registry members may ask their clinician or genetic counselor to add specific ophthalmic exam and measurement results to the profile. This is done through the clinical portal which also uses a series of drop-down menus to expedite entry and standardize data. Clinicians cannot see the participant data when adding the clinical exam data. Participants are encouraged to collect this data at each medical exam, to create a longitudinal clinical data set.

Access to de-identified data or study recruitment assistance is available to qualified investigators who may inquire by contacting Coordinator@MyRetinaTracker.org. A process that maintains patient anonymity and privacy protection, exists for researchers with Institutional Review Board-approved projects who wish to contact registry participants of interest.

02

Conditions studied

  • Eye Diseases Hereditary
  • Retinal Disease
  • Achromatopsia
  • Bardet-Biedl Syndrome
  • Bassen-Kornzweig Syndrome
  • Batten Disease
  • Best Disease
  • Choroidal Dystrophy
  • Choroideremia
  • Cone Dystrophy
  • Cone-Rod Dystrophy
  • Congenital Stationary Night Blindness
  • Enhanced S-Cone Syndrome
  • Fundus Albipunctatus
  • Goldmann-Favre Syndrome
  • Gyrate Atrophy
  • Juvenile Macular Degeneration
  • Kearns-Sayre Syndrome
  • Leber Congenital Amaurosis
  • Refsum Syndrome
  • Retinitis Pigmentosa
  • Retinitis Punctata Albescens
  • Retinoschisis
  • Rod-Cone Dystrophy
  • Rod Dystrophy
  • Rod Monochromacy
  • Stargardt Disease
  • Usher Syndrome

Keywords

  • inherited retinal degenerative disease
  • retinitis pigmentosa
  • Usher
  • Leber
  • Bardet-Biedl
  • Batten
  • Best
  • cone dystrophy
  • cone-rod dystrophy
  • choroideremia
  • congenital night blindness
  • enhanced s-cone
  • cone monochromacy
  • Goldmann-Favre
  • Kearns-Sayre
  • Refsum
  • retinoschisis
  • rod-cone dystrophy
  • rod dystrophy
  • rod monochromacy
  • Sorsby pseudoinflammatory dystrophy
  • stargardt
  • achromatopsia
  • juvenile inherited macular degeneration
  • cone dichromacy
  • cone trichromacy
  • Charcot-Marie-Tooth
  • albipunctate dystrophy
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Affected individuals, all ages including minors registered by their parent or guardian.

Inclusion criteria

  • Diagnosed with an inherited retinal degenerative disease OR

Exclusion criteria

Exclusion Criteria:

  • Glaucoma only
  • Diabetic retinopathy only
  • Non-retinal disease
  • Not heritable retinal disease
04

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
20,000 participants (estimated)
Target follow-up
20 Years
Patient registry
Yes
05

What researchers measure

Primary outcomes

  1. Number of Participants with Rare Diagnoses Within the Inherited Retinal Degenerative Disease Category as Defined by Clinical Evaluation

    Participant profiles broken out by disease category and genetic diagnosis

    Time frame: Data collection is ongoing, up to 20 years.

06

Study locations

1 of 1 sites recruiting
  • Foundation Fighting Blindness
    Columbia, Maryland 21045, United States
    Recruiting
07

References and documents

08

Registry details

Key details

Study ID
NCT02435940
Lead sponsor
Foundation Fighting Blindness
Responsible party
Sponsor
First posted
May 6, 2015
Start date
Jun 2014
Primary completion
Jun 2037 (estimated)
Completion
Jun 2037 (estimated)
Last update
May 19, 2026

Study contacts

Registry Coordinator
Contact
Coordinator@MyRetinaTracker.org
800-683-5555 ext. 1594
Todd Durham, PhD
principal investigator · Senior Vice President, Clinical and Outcomes Research

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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