Pyelonephritis: all 79 studies

Page 1 of 1. Open to participants first (12), then studies with results posted, then the rest; newest registration first within each.

• Fosfomycin Trometamol Compared With an Alternative Active Antibiotic as Step-down Therapy for the Treatment of Acute Pyelonephritis Due to Escherichia Coli in Elderly Women : a Randomized, Multicenter, Non-inferiority TrialNot yet recruitingNCT07928063Phase 3
• This is a Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ertapenem-zidebactam Versus Ceftazidime-Avibactam in the Treatment of Hospitalized Adult Patients With Complicated Urinary Tract Infection or Acute PyelonephritisNot yet recruitingNCT07840105Phase 2
• Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL StudyRecruitingNCT07579312
• Population Pharmacokinetics of Temocillin in Acute Enterobacterial Pyelonephritis in ChildrenRecruitingNCT07070102
• Clinical Trial Comparing Oral Versus Intravenous Cefuroxime in Pregnant Women with PyelonephritisRecruitingNCT06527560Phase 4
• A Trial of Intravenous HRS-8427 in the Treatment of Adults With Complicate Urinary Tract Infection, Including Acute PyelonephritisNot yet recruitingNCT06144060Phase 2
• NRX-101 for Complicated Urinary Tract Infection (UTI) Including PyelonephritisNot yet recruitingNCT06128213Phase 2
• Efficacy of 7 Days Versus 14 Days of Antibiotic Therapy for Acute Pyelonephritis in Kidney Transplant Recipients, a Multicentre Randomized Non-inferiority Trial.RecruitingNCT05597540Phase 3
• 3-day IV Antibiotic Treatment Versus 3-day IV Followed by 7-day Oral Antibiotic Treatment for AP in ChildrenRecruitingNCT05544565Phase 4
• Evaluation of the Efficacy and Safety of Intravenous Imipenem/Cilastatin/XNW4107 in Comparison With Meropenem in Hospitalized Adults With cUTI Including AP (EudraCT no. 2022-000061-40)Not yet recruitingNCT05204368Phase 3
• The Validity of the Quick Renal MRI in Pediatric Kidney DiseaseRecruitingNCT03959163Not applicable
• Study of Cefepime-tazobactam (FEP-TAZ) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)Not yet recruitingNCT03630081Phase 3
• Patient-Directed Antimicrobial Duration in Acute Uncomplicated PyelonephritisCompletedNCT06127160Phase 4Results posted
• Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated PyelonephritisCompletedNCT05887908Phase 3Results posted
• Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)CompletedNCT04979806Phase 3Results posted
• Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)CompletedNCT03788967Phase 3Results posted
• IV or IV/PO Omadacycline vs. IV/PO Levofloxacin for the Treatment of Acute PyelonephritisCompletedNCT03757234Phase 2Results posted
• Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract InfectionsCompletedNCT03445195Phase 2Results posted
• Management of Sub-Clinical Bacteriuria in PregnancyCompletedNCT03275623Phase 4Results posted
• MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)CompletedNCT03230838Phase 2Results posted
• Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP InfectionsCompletedNCT02753946Phase 2/3Results posted
• Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014)CompletedNCT02728089Phase 3Results posted
• Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and APCompletedNCT02166476Phase 3Results posted
• Finafloxacin for the Treatment of cUTI and/or Acute PyelonephritisCompletedNCT01928433Phase 2Results posted
• Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)CompletedNCT01599806Phase 3Results posted
• Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)CompletedNCT01595438Phase 3Results posted
• Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003)CompletedNCT01505634Phase 2Results posted
• GSK2251052 in Complicated Urinary Tract InfectionTerminatedNCT01381549Phase 2Results posted
• Preventing Urinary Tract Infection Post-SurgeryCompletedNCT01346774Phase 2Results posted
• Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including PyelonephritisCompletedNCT01345929Phase 3Results posted
• A Safety and Tolerability Study of Doripenem Compared With Cefepime in Children Hospitalized With Complicated Urinary Tract InfectionsTerminatedNCT01110408Phase 3Results posted
• A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP)CompletedNCT01096849Phase 2Results posted
• Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract InfectionsCompletedNCT00921024Phase 2Results posted
• Plasma NGAL in APN PatientsCompletedNCT06802796
• A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Children With Complicated Urinary Tract Infection, Including Acute PyelonephritisActive, not recruitingNCT06672978Phase 2
• A Trial of HRS-8427 in the Treatment of Adults With Complicated Urinary Tract Infection, Including Acute PyelonephritisCompletedNCT06569056Phase 3
• Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)CompletedNCT06526884Not applicable
• Factors and Prognosis of Obstructive Pyelonephritis PatientsCompletedNCT06299215
• P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant EnterobacteralesCompletedNCT05905055Phase 3
• Bacterial Metallophores in the Diagnosis of Acute PyelonephritisStatus unknownNCT05674032
• Meropenem-FL058 Phase 2 Study in the Treatment of Complicated Urinary Tract InfectionsStatus unknownNCT05060419Phase 2
• Expanded Access Use of Sulopenem Etzadroxil/Probenecid for Complicated Urinary Tract InfectionNo longer availableNCT04682834
• Cefuroxime Resistance in PyelonephritisCompletedNCT04616352
• Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by UrolithiasisCompletedNCT04594161Not applicable
• A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)CompletedNCT04505683Phase 2/3
• Bedside Ultrasonography in Acute Patients With Suspected Kidney InvolvementCompletedNCT03873701
• CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative BacteriaCompletedNCT03477422Phase 3
• Treating Pyelonephritis an Urosepsis With PivmecillinamCompletedNCT03282006Phase 4
• 7-day Compared With 10-day Antibiotic Treatment for Febrile Urinary Tract Infections in ChildrenStatus unknownNCT03221504Not applicable
• Impact on the Intestinal Microbiota of Treatment With Ceftriaxone in Women's Acute Community PyelonephritisCompletedNCT03179384Phase 4
• Pharmacokinetics of Ciprofloxacin in Pediatric PatientsCompletedNCT02598362Phase 4
• Special Drug Use Investigation of Ciproxan Injection in PediatricsCompletedNCT02555059
• Proteinuria During Acute Pyelonephritis In PregnancyCompletedNCT02536638
• Prospective Comparative Study About Treatment of Asymptomatic Bacteriuria in Kidney Transplant Recipients.CompletedNCT02373085Not applicable
• Impact of Six Patient Information Leaflets (PIL) on Doctor Patient CommunicationCompletedNCT02246361Phase 4
• Oral Omega-3 for Reduction of Kidney Scar Due to Pyelonephritis in ChildrenStatus unknownNCT02192580Phase 3
• Effect of Acetylcysteine in Pediatric Acute Pyelonephritis.CompletedNCT02080182Phase 2
• Dexamethasone Administration in 1st Episode of Febrile Urinary Tract InfectionCompletedNCT02034851
• L-carnitine on the Prevention of Renal Scarring in Acute PyelonephritisStatus unknownNCT02007889Phase 3
• Cranberry-lingonberry Juice Started During Acute Infection in Prevention of Urinary Tract Infections in ChildrenCompletedNCT01861353Not applicable
• Efficacy and Pharmacokinetic/Pharmacodynamic Parameters of Cefoxitin in Women With Acute Pyelonephritis Without Severity Symptoms Due to Extended-spectrum β-lactamase Producing Escherichia ColiTerminatedNCT01820793Not applicable
• Antibiotic Treatment Versus no Therapy in Kidney Transplant Recipients With Asymptomatic BacteriuriaStatus unknownNCT01771432Not applicable
• Community-Associated Uropathogen Antimicrobial Resistance Among Emergency Department Patients With Acute PyelonephritisCompletedNCT01641029
• Prospective Study in the EmergencyTerminatedNCT01628900Phase 2
• Prognostic Indicators as Provided by the EPIC ClearViewCompletedNCT01476995
• Efficacy and Safety Study of Short-term Antibiotic for Pyelonephritis in WomenCompletedNCT01390623Phase 4
• Antibiotic Education for Children in an Emergency Care UnitCompletedNCT00948779Not applicable
• Kinetics of Biomarkers in Acute PyelonephritisCompletedNCT00805181
• Antibiotic Prophylaxis in Children With PyelonephritisWithdrawnNCT00752375Phase 3
• Short-term Antibiotic Therapy for Pyelonephritis in ChildhoodTerminatedNCT00724256Phase 3
• Risk Factors for Recurrent Urinary Tract Infection in ChildrenCompletedNCT00528476
• A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral RefluxCompletedNCT00382343Phase 4
• A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Complicated Urinary Tract InfectionsCompletedNCT00258089Phase 3
• Safety and Efficacy Study of the Treatment of Kidney Infections With Short Course LevofloxacinTerminatedNCT00239161Phase 4
• Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or PyelonephritisCompletedNCT00229021Phase 3
• Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or PyelonephritisCompletedNCT00210990Phase 3
• A Comparison of the Effectiveness and Safety of Levofloxacin to That of Ciprofloxacin in Treating Complicated Urinary Tract Infection and Acute Pyelonephritis.CompletedNCT00210886Phase 3
• Contrast-Enhanced US of Spleen, Liver and KidneyStatus unknownNCT00190281
• Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years OldCompletedNCT00136656Phase 4

← Pyelonephritis overview