Prosthesis Failure clinical trials
The registry lists 119 studies for Prosthesis Failure across more than 10 countries. 35 are recruiting or about to start. 93 of them are mainly about Prosthesis Failure (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Who runs them
Mansoura University (18) · Istituto Ortopedico Rizzoli (7) · Malo Clinic (6) · Cairo University (5) · Groupe SEBBIN (3) · Aesculap AG (3) · University Hospital, Ghent (3) · University of Liege (2)
What is being tested here
Drugs under test in Prosthesis Failure studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026The ReTAVI Prospective Observational Registry · Institut für Pharmakologie und Präventive Medizin
- Dec 2026Survival of Implant-Supported All-Ceramic Prostheses · University of Florida
- Dec 2026Transcatheter Aortic Valve Implantation Versus Standard Surgical Aortic Valve Replacement · Centre Cardiologique du Nord
- Jan 2027Evaluation of the Clinical Outcomes of the Total Knee ps Prosthesis Implanted With the Use of Inertial Sensors · Istituto Ortopedico Rizzoli
- Jun 2027Clinical Performance of All-on-4 PEEK and Conventional Prostheses · University of Sharjah
- Sep 2027Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR · Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Who these studies take
Of the 25 Prosthesis Failure studies recruiting now, 16 (64%) set no upper age limit and 3 (12%) stop at 75 or younger. 5 (20%) take children under 18. 2 (8%) are for women only and 0 (0%) for men only; 6 (24%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (20%) | 5 (20%) |
| 18 | 19 (76%) | 17 (68%) |
| 30 | 22 (88%) | 20 (80%) |
| 40 | 22 (88%) | 20 (80%) |
| 50 | 24 (96%) | 22 (88%) |
| 65 | 23 (92%) | 21 (84%) |
| 75 | 22 (88%) | 20 (80%) |
| 85 | 20 (80%) | 18 (72%) |
Across all 119 studies, recruiting or not: 34% stop at 75 or younger and 11% at 65; 14% take children; 5% are for women only and 0% for men only; 41% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Prosthesis Failure studies take
Of 50 interventional studies with no phase under Prosthesis Failure, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 18 mo9–42 · 50 studies | — | 18 mo10–51 · 48 studies |
| Observational | 181 mo57–184 · 28 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 119. Browse all 119 → or search them.
- The ReTAVI Prospective Observational RegistryRecruitingNCT0560145311 countries
- Multicenter Mpact DM FranceRecruitingNCT058188911 country
- Exactech Vantage Total Ankle System Post Market Clinical Follow-Up - US OnlyRecruitingNCT056195881 country
- Vantage Mobile Bearing Total Ankle System Post Market Clinical Follow-up (Outside US)RecruitingNCT056918682 countries
- Evaluation of 5-year Survival and Clinical Outcomes in Patients Undergoing Total Knee Arthroplasty With a Polyethylene Tibial ComponentRecruitingNCT07544264Not applicable1 country
- Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Revision Hip Prosthesis SystemRecruitingNCT076532951 country
- Evaluation of the Clinical Outcomes of the Total Knee ps Prosthesis Implanted With the Use of Inertial SensorsRecruitingNCT063210421 country
- Poly vs Hybrid Glenoid in Stemless aTSARecruitingNCT07520721Not applicable1 country
- Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVRRecruitingNCT05459233Not applicable2 countries
- Radiographic Stability of Hip Prosthesis Prior to Revision SurgeryNot yet recruitingNCT069245673 countries
- Comparison of Effectiveness of Gingival Displacement Using Retraction Cord and Aluminum Chloride GelRecruitingNCT07255976Phase 41 country
- Abutment Analysis of Metallic Denture Frameworks in Mandibular Kenedy Class III CasesNot yet recruitingNCT07215208Not applicable
- Long-term Survival of THA After Pelvic and/or Femoral OsteotomyNot yet recruitingNCT06959498
- Medium-term Results of the LPS™ System for Segmental Resection of the Distal Femur, a Multicenter Retrospective Study (RESIF)Enrolling by invitationNCT069289481 country
- TAVR: The Impact of Prothesis Positioning on Valvular and Coronary HemodynamicsRecruitingNCT06896227Not applicable1 country
- New Stereophotogrammetry System to Capture Complete-arch ImpressionRecruitingNCT067452321 country
- Randomized Evaluation for Failed TAVRNot yet recruitingNCT06400342Not applicable
- SEBBIN Silicone Gel-filled Testicular ImplantsRecruitingNCT049684702 countries
- SEBBIN Round, Anatomical and Biconvex Gluteal ImplantsRecruitingNCT050627332 countries
- Sexual Functioning After Erection Prosthesis Placement in Post Phalloplasty Transgender PersonsRecruitingNCT066397761 country
- Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular ImplantsRecruitingNCT050978201 country
- Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.RecruitingNCT05883553Not applicable2 countries
- Clinical Performance of All-on-4 PEEK and Conventional ProsthesesEnrolling by invitationNCT06388395Not applicable1 country
- Nutrition Impact on Immunotherapy of CancerRecruitingNCT06500234Phase 31 country
- Clinical Success of Anterior and Posterior Crowns in a Group of Children Treated Under General AnesthesiaNot yet recruitingNCT06201481
- Four-unit Implant Supported Fixed Partial Dentures Fabricated From Different MaterialsRecruitingNCT064222601 country
- Evaluation of Locator Versus TITACH Attachment for Mandibular Overdentures.RecruitingNCT06228859Not applicable1 country
- Clinical and Functional Outcome of the MobileLink Acetabular Cup System in the Short-, Mid-, and Longterm Follow-upRecruitingNCT046885932 countries
- Accuracy of 3-dimensional Printed Implant Cast Versus Conventional Stone Cast for Edentulous Mandibular ArchEnrolling by invitationNCT06050187Not applicable1 country
- Evaluation of Single-unit Implant-supported Prostheses Survival Using CoCr Prosthetic Abutments: Prospective Observational StudyRecruitingNCT056490851 country
- Clinical and Radiographical Evaluation of CAD-CAM Crowns With and Without Deep Margin ElevationRecruitingNCT06114030Not applicable1 country
- Edentulous Maxilla Opposed by 2-implant Mandibular Overdenture?Enrolling by invitationNCT06050213Not applicable1 country
- Cup Revisions Through Anterior or Posterolateral Approach: an RCTEnrolling by invitationNCT05508958Not applicable1 country
- RCT: Titanium vs FCZ vs Zirconia FrameworkRecruitingNCT05296291Not applicable1 country
- Patient-reported Outcome Measures in Patient Underwent Total Hip and Knee ArthroplastyRecruitingNCT049600981 country
- Comparison of the Balloon-Expandable Edwards Valve and Self-Expandable CoreValve Evolut R or Evolut PRO System for the Treatment of Small, Severely Dysfunctional Surgical Aortic Bioprotheses. The 'LYTEN' TrialActive, not recruitingNCT03520101Not applicable1 country
- Clinical Performance of All-ceramic Posterior Crowns. A Randomized, Prospective Clinical.Active, not recruitingNCT04272112Not applicable1 country
- Survival of Implant-Supported All-Ceramic ProsthesesActive, not recruitingNCT017298581 country
- Clinical Evaluation of Implants Restored With Advanced Lithium Disilicate Screw-retained CrownsActive, not recruitingNCT057525391 country
- Investigation on Failure Time Analysis of a New TPE Material in the Iceform LinerCompletedNCT05040165Not applicable1 country
- Transcatheter Aortic Valve Implantation Versus Standard Surgical Aortic Valve ReplacementActive, not recruitingNCT052612041 country
- Plasmafit® Revision Structan® Hip Endoprosthesis CupActive, not recruitingNCT042559661 country
- Clinical Study of a 3D Shaded Zirconia for Chairside CAD/CAM RestorationsActive, not recruitingNCT067135771 country
- Risk of Revision Following Knee Arthroplasty in Bariatric Surgery PatientsCompletedNCT064337001 country
- Efficacy of Robot-assisted Technique vs Conventional Technique in Preventing Early Micromobilisation After UKAActive, not recruitingNCT05204797Not applicable1 country
- Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever ExtensionCompletedNCT056762681 country
- Impact of Retro-molar Pad Demarcation on Complete Denture Wearers' SatisfactionCompletedNCT07246343Not applicable1 country
- Limb Health and Socket Pressure in Response to Powered Ankle ProthesesCompletedNCT05112679Not applicable1 country
- Monocer AOANJRR Registry-nested StudyActive, not recruitingNCT058225051 country
- Single Tooth Implant-supported Fixed Prosthetic Rehabilitation Using PEEK.TerminatedNCT05589532Not applicable1 country