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Not yet recruitingNCT07215208Updated Oct 10, 2025

Abutment Analysis of Metallic Denture Frameworks in Mandibular Kenedy Class III Cases

An interventional study of CAD/CAM metallic partial denture frameworks and Conventional metallic partial denture frameworks in Occlusion and Prosthesis Durability, sponsored by Cairo University. Not yet recruiting. Per ClinicalTrials.gov, last updated 2025-10-10.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jan 2026, 10 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
22
Allocation
Randomized
Sex
All
01

Study summary

This study is aimed to compare CAD/CAM (digitally fabricated) metallic partial denture frameworks to conventionally fabricated metallic partial denture frameworks in mandibular Kennedy class-III arches in terms of abutment health and occlusal analysis

Read the detailed description

Traditional metallic partial dentures with cobalt-chromium frameworks and clasps considered a reliable choice because they're affordable, durable and have a resistance to distortion. However, the fabrication of traditional metallic partial dentures involves several manual steps, like pouring of the stone casts, surveying the hard tissue and soft tissue undercuts to choose the best path of insertion, and meticulously waxing each component (major and minor connectors, rests, clasps, and denture base retainers) directly onto the cast. This hands-on process can result in some fabrication errors, which by in turn can increase the stresses on the teeth supporting the denture (abutments) and even other non-abutment teeth.

CAD/CAM technology is increasingly being used for the fabrication of metallic partial denture frameworks; it has been highlighting in several investigations. The workflow starts with an intra oral digital scan of the oral cavity, to generate a 3D digital model, that allows for electronic surveying. The metallic partial denture frameworks are then designed virtually using specialized software, after which a wax pattern is created by milling or rapid prototyping. Then the wax pattern would be casted conventionally into metallic partial denture frameworks. The key advantages are simplifying the fabrication process, enhance the accuracy of fit, and reduce the stresses on abutment teeth, significant time savings, and reduction of the potential errors inherent in traditional multi-step lab procedures

02

Conditions studied

  • Occlusion
  • Prosthesis Durability

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03

In context

Prosthesis Failure

119 studies on the registry are indexed under Prosthesis Failure; 35 are open to participants now.

This study's planned enrollment of 22 is below the median of 36 across 69 interventional studies indexed under Prosthesis Failure.

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Lead sponsor

Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with unilateral bounded saddles in the mandible (Kennedy class III).
  • Opposing dentition is fully intact or restored.
  • Sufficient inter-arch space.
  • Angle's class I maxilla-mandibular relationship.

Exclusion criteria

Exclusion Criteria:

  • Periodontal affection of the abutment teeth.
  • Skeletal mal-relation.
  • Unmotivated patients to maintain adequate oral hygiene to follow up.
  • Patients with neuromuscular and Psychiatric disorders.
  • Systematic disease affecting bone and periodontal health.
  • Insufficient inter-arch space.
  • Patients with physical disabilities that could affect follow up.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
22 participants (estimated)

Study arms

  • Experimental
    CAD/CAM metallic partial denture frameworks

    The digital technology makes it much easier in fabricating the prosthesis, so by the aid of this technology we can make accurate occlusal scan and jaw relation without annoying of the patient with the impression material. The software makes it much easier in designing and planning for proper established removable metallic partial denture, with one tap we can print the designed wax pattern and continue in the conventional steps of manufacturing the metallic partial denture

    Other: CAD/CAM metallic partial denture frameworks

  • Active comparator
    Conventional metallic partial denture frameworks

    The conventional fabricated metallic partial dentures have been the standard method for fabricating the metallic frameworks. It is a reliable treatment option for the partially edentulous patients and the most commonly used for it is advantageous. The advantages of conventional metallic partial dentures are it considered to be more rigid even if in thin sections, has higher stiffness and strength, thanks to good thermal conductivity of metal it can conduct heat and cold, can be designed to minimize tissue coverage

    Other: Conventional metallic partial denture frameworks

Interventions

  • OtherCAD/CAM metallic partial denture frameworks

    The CAD/CAM workflow starts with scanning of the physical model (master cast) to create a 3D virtual representation. Dental professionals then digitally analyze this virtual model and design the metallic partial denture frameworks using specialized computer software. Once the design is finalized, a wax pattern of the framework is either milled or 3D printed. Then proceeding with this wax pattern to fabricate the final metal partial denture framework, either by conventional casting process, or milling of the metallic framework

  • OtherConventional metallic partial denture frameworks

    The metallic partial denture frameworks have proven to be affordable and convenient treatment option for partially dentate patients for it is rigidity and durability. It can be used in thin sections and provide high strength and stiffness. However, metallic partial denture frameworks also come with several drawbacks. A significant concern for some patients is the metallic display, which can lead to poor esthetics. Other disadvantages include increased prosthesis weight, a potential metallic taste, and a tendency for plaque accumulation. Additionally, they can induce stresses on the abutment teeth

06

What researchers measure

Primary outcomes

  1. Abutment health mobility

    Periotest, Periotest value (PTV) which ranges from -8 to +50

    Time frame: 3 months

Secondary outcomes

  1. Gingival bleeding index

    Löe and Silness Gingival Index (GI), GI scale (scores) 0 -3 (with 0 being normal and 3 being severe inflammation)

    Time frame: 3 months

Other outcomes

  1. Occlusal Analysis

    OccluSense Device, Force distribution per tooth

    Time frame: 3 months

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 10, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07215208
Lead sponsor
Cairo University
Responsible party
Samah Ahmed Abdallah Sharaka (PhD degree student, Prosthetic Dentistry Department, Cairo University) — Principal investigator
First posted
Oct 10, 2025
Start date
Oct 2025 (estimated)
Primary completion
Jan 2026 (estimated)
Completion
Jan 2026 (estimated)
Last update
Oct 10, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

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