ClinicalTrials.gg
CompletedNCT05676268Updated Jan 22, 2026

Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension

An observational study in Dental Implant Failed, Prosthesis Failure and Peri-Implantitis, sponsored by University of Bern. Completed at 1 site in Switzerland. Open to participants aged 18 Years to 99 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-22.

Sponsored by University of Bern · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
35
Ages
18 Years to 99 Years
Sex
All
01

Study summary

To report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months.

Read the detailed description

Patients with full ceramic FDPCs in anterior and posterior areas will be clinically and radiographically re-evaluated. Mesial and distal radiographic marginal bone levels (mBLs) from baseline (i.e. delivery of FDPC) to the follow-up examination were calculated and compared between implant surfaces adjacent to and distant from the cantilever extension. Implant survival rate (%), pocket probing depth (PPD), presence/ absence of bleeding on probing (BoP) and presence/absence of mechanical/technical and biological complications were recorded.

02

Conditions studied

  • Dental Implant Failed
  • Prosthesis Failure
  • Peri-Implantitis
03

In context

Prosthesis Failure

119 studies on the registry are indexed under Prosthesis Failure; 35 are open to participants now.

This study's enrollment of 35 is below the median of 119 across 49 observational studies indexed under Prosthesis Failure.

Browse Prosthesis Failure studies →

Lead sponsor

University of Bern is the lead sponsor of 209 studies on the registry; 47 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 99 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients with missing teeth rehabilitated with dental implants supporting partial fixed dental prostheses with cantilever extensions

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients aged ≥18 years
  • Written
  • Patients with systemic health or controlled medical conditions
  • Patients with healthy or treated periodontal conditions
  • Patients enrolled in regular supportive periodontal therapy (SPT)
  • Patients without clinical signs of bruxism and/or oral parafunctions
  • 2 osseointegrated dental implants in the canine or posterior areas of maxilla and mandible following transmucosal placement and healing of 3-6 months
  • Tissue level solid-screw implants with a sand-blasted and acid- etched (SLA) surface with an endosseous diameter of 3.3, 4.1 or 4.8 mm, a length of 8, 10 or 12 mm, a shoulder diameter of 4.8 mm and a supracrestal machined neck with a height of 1.8 or 2.8 mm (Straumann® Dental Implant System, Institut Straumann AG, Basel, Switzerland)
  • Full-ceramic
  • Utilization of prefabricated titanium abutments
  • Cemented (3M™ ESPE Ketac™ Cem, Seefeld, Germany) or screw-retained fixed dental prostheses with a mesial or distal cantilever extension (FDPCs)
  • Cantilever extension corresponding to 1 premolar unit (i.e., 6-7 mm)
  • Absence of occlusal contacts or guidance on the cantilever extension at baseline
  • Opposing dentition consisting of natural teeth or fixed or removable prosthetic restorations
  • Availability of a periapical radiograph at baseline (i.e. FDPC delivery)
  • Availability of PPD measurements (mm) taken at baseline at 4 sites/implant with a graduated Michigan periodontal probe (Deppeler SA, Rolle, Switzerland)
  • Availability of BoP measurements (%) (Lang et al., 1986) taken at baseline at 4 sites/implant with a graduated Michigan periodontal probe (Deppeler SA, Rolle, Switzerland).

Exclusion criteria

Exclusion Criteria:

  • Untreated or active periodontal diseases
  • Immediate implant placement (i.e., Type I implant placement according to Hämmerle et al., 2004)
  • FDPCs in the aesthetic zone (i.e., replacement of maxillary or mandibular incisors)
  • FDPCs supported by hollow-screw and hollow-cylinder implants
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
35 participants (actual)
Patient registry
No

Groups and cohorts

  • Patients with oral implants supporting full ceramic fixed dental prostheses

    Procedure: Implant-supported fixed dental prostheses with cantilever extension

Interventions

  • ProcedureImplant-supported fixed dental prostheses with cantilever extension

    Healthy patients in need of replacement of missing teeth with dental implants supporting partial fixed dental prostheses with cantilever extensions

06

What researchers measure

Primary outcomes

  1. Implant survival rate

    Percentage of dental implants present at follow-up visit

    Time frame: 12 months

Secondary outcomes

  1. Peri-implant marginal bone level changes

    Time frame: 12 months

  2. Number of technical complications

    Time frame: 12 months

  3. Number of mechanical complications

    Time frame: 12 months

  4. Number of Biological complications

    Time frame: 12 months

07

Study locations

1 site
  • Department of Periodontology, University of Bern
    Bern, 3010, Switzerland
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jan 2023 to primary completion in Sep 2023, 8 months.

Of 28 observational studies under Prosthesis Failure, half reached primary completion within 181 months of starting (the median), counting those still running; a quarter within 57 and three quarters within 184. This study's 8 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 22, 2022
First posted
Jan 9, 2023
StartActual
Jan 2, 2023
Primary completionActual
Sep 30, 2023
CompletionActual
Dec 31, 2023
Last update
Jan 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jan 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05676268
Lead sponsor
University of Bern
Responsible party
Sponsor
First posted
Jan 9, 2023
Start date
Jan 2, 2023
Primary completion
Sep 30, 2023
Completion
Dec 31, 2023
Last update
Jan 22, 2026

Study contacts

Andrea Roccuzzo
principal investigator · University of Bern

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.

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