Pneumoperitoneum clinical trials
The registry lists 134 studies for Pneumoperitoneum across more than 10 countries. 28 are recruiting or about to start. 87 of them are mainly about Pneumoperitoneum (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Who runs them
Fatih Sultan Mehmet Training and Research Hospital (4) · Radboud University Medical Center (4) · Ege University (4) · Yonsei University (4) · ASST Fatebenefratelli Sacco (4) · Engin Çetin (3) · Bursa Yuksek Ihtisas Training and Research Hospital (2) · Western Galilee Hospital-Nahariya (2)
What is being tested here
Drugs under test in Pneumoperitoneum studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexamethasone | 1 | 0 | 1 |
| Remimazolam | 1 | 0 | 1 |
| Bupivacaine | 1 | 0 | 1 |
| Oxycodone | 1 | 0 | 1 |
| Propofol | 0 | 0 | 3 |
| Dexmedetomidine | 0 | 0 | 3 |
| Remifentanil | 0 | 0 | 2 |
| Rocuronium | 0 | 0 | 2 |
| Magnesium | 0 | 0 | 1 |
| Lidocaine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026The Turbine-based CO2 Insufflator Pediatric Feasibility Study · Erasmus Medical Center
- Jan 2027High Versus Low Pneumoperitoneum PressUre for Parenchymal Transection in Minimally Invasive Major Liver Surgery · University Hospital Heidelberg
- Jan 2027Low Gas Pressure vs Standard Gas Pressure in Robotic Surgery · Weill Medical College of Cornell University
- Feb 2027Early Kidney Injury Biomarkers in Gynecologic Laparoscopic Surgery · Medipol University
- Apr 2027Short Title: Standard vs. Lower Pressure Pneumoperitoneum · Cedars-Sinai Medical Center
- Jun 2027Study of the Relationship Between Curarization and Pneumoperitoneum in Laparoscopic Surgery · Poitiers University Hospital
- Jun 2027VC-AF vs FCV in Obese Patients Undergoing Laparoscopic Surgery · Kocaeli University
- Jul 2027Preoperative Breathing Exercise Training and Postoperative Delirium After Robotic Radical Prostatectomy · ALİ DEMİRTAŞ
- Jul 2027HFNC for Postoperative Atelectasis After Laparoscopic Surgery · Bursa Yuksek Ihtisas Training and Research Hospital
- Jul 2027vNOTES vs Laparoscopy: Respiratory Mechanics and Hemodynamics · Bursa Yuksek Ihtisas Training and Research Hospital
Who these studies take
Of the 13 Pneumoperitoneum studies recruiting now, 8 (62%) set no upper age limit and 3 (23%) stop at 75 or younger. 1 (8%) take children under 18. 3 (23%) are for women only and 3 (23%) for men only; 1 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (8%) | 1 (8%) |
| 18 | 10 (77%) | 10 (77%) |
| 30 | 9 (69%) | 9 (69%) |
| 40 | 9 (69%) | 9 (69%) |
| 50 | 9 (69%) | 9 (69%) |
| 65 | 9 (69%) | 9 (69%) |
| 75 | 8 (62%) | 7 (54%) |
| 85 | 8 (62%) | 7 (54%) |
Across all 134 studies, recruiting or not: 37% stop at 75 or younger and 25% at 65; 13% take children; 13% are for women only and 11% for men only; 22% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pneumoperitoneum studies take
Of 40 interventional studies with no phase under Pneumoperitoneum, half reached primary completion within 8 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 8 mo4–14 · 40 studies | — | 8 mo4–14 · 40 studies |
| Observational | 11 mo5–17 · 26 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Newly registered3
- Effect of Prophylactic Dexamethasone vs Placebo on Airway Dimensions Assessed by Ultrasonography in Patients Undergoing Laparoscopic CholecystectomyNov 5, 2026NCT07918495
- Fluid Responsiveness in Laparoscopic Surgery: End-Expiratory Occlusion Test Versus Mini-Fluid ChallengeNov 2, 2026NCT07911059
- VC-AF vs FCV in Obese Patients Undergoing Laparoscopic SurgeryOct 15, 2026NCT07875530
Studies
Recruiting first, then most recently updated. Showing 50 of 134. Browse all 134 → or search them.
- Effect of Prophylactic Dexamethasone vs Placebo on Airway Dimensions Assessed by Ultrasonography in Patients Undergoing Laparoscopic CholecystectomyNot yet recruitingNCT07918495Phase 4
- Fluid Responsiveness in Laparoscopic Surgery: End-Expiratory Occlusion Test Versus Mini-Fluid ChallengeNot yet recruitingNCT07911059
- VC-AF vs FCV in Obese Patients Undergoing Laparoscopic SurgeryRecruitingNCT078755301 country
- The Turbine-based CO2 Insufflator Pediatric Feasibility StudyRecruitingNCT07715968Not applicable1 country
- Effect Of Trendelenburg Position And Pneumoperitoneum On Optic Nerve Sheath Diameter In Robot-Assisted ProstatectomyRecruitingNCT074911981 country
- Maneuvers to Reduce Laparoscopic PainNot yet recruitingNCT07583433Not applicable1 country
- Individualized vs Standard PEEP and Oxygen Reserve Index in Laparoscopic Hernia SurgeryNot yet recruitingNCT077755731 country
- Low Gas Pressure vs Standard Gas Pressure in Robotic SurgeryRecruitingNCT07710352Not applicable1 country
- Preoperative Breathing Exercise Training and Postoperative Delirium After Robotic Radical ProstatectomyNot yet recruitingNCT07766603Not applicable1 country
- Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES HysterectomyRecruitingNCT07730970Not applicable1 country
- Low-Residue Diet Versus Rectal Enema Before Laparoscopic Surgery for Endometrial CancerRecruitingNCT07702799Not applicable1 country
- Early Kidney Injury Biomarkers in Gynecologic Laparoscopic SurgeryNot yet recruitingNCT077042421 country
- HFNC for Postoperative Atelectasis After Laparoscopic SurgeryNot yet recruitingNCT07676760
- vNOTES vs Laparoscopy: Respiratory Mechanics and HemodynamicsNot yet recruitingNCT076679071 country
- Timing of Recruitment Maneuver in Robotic Prostate SurgeryRecruitingNCT07662642Not applicable1 country
- Does Trendelenburg Positioning During Pulmonary Recruitment Breaths Affect Post-laparoscopy Shoulder PainNot yet recruitingNCT07631728Not applicable
- Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic SurgeryNot yet recruitingNCT07251101Not applicable1 country
- Pneumoperitoneum Duration and Bicarbonate Changes in Laparoscopic Hernia SurgeryRecruitingNCT074735831 country
- Study of the Relationship Between Curarization and Pneumoperitoneum in Laparoscopic SurgeryNot yet recruitingNCT07005518
- Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic SurgeriesNot yet recruitingNCT06929078Not applicable1 country
- Predictors of Postoperative Complications in Surgery With Pneumoperitoneum in the Trendelenburg PositionRecruitingNCT066851591 country
- Impact of Using the Airseal System with Ultra-low Pneumoperitoneum in Patients Undergoing Robot-assisted Radical Prostatectomy: a Prospective, Comparative, Randomized Clinical Study.RecruitingNCT06784986Phase 41 country
- High Versus Low Pneumoperitoneum PressUre for Parenchymal Transection in Minimally Invasive Major Liver SurgeryNot yet recruitingNCT06770803Not applicable
- Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia RepairNot yet recruitingNCT06737068Not applicable1 country
- Short Title: Standard vs. Lower Pressure PneumoperitoneumRecruitingNCT06338865Not applicable1 country
- Comparison of the Effects of Different PEEP Values With USG on Optic Nerve Sheath DiameterNot yet recruitingNCT06224868Not applicable
- Recruitment-to-inflation Ratio to Set Positive End-expiratory Pressure for Laparoscopic/Robotic Surgery: a Multicenter StudyRecruitingNCT057025541 country
- Respiratory and Hemodynamic Implications of Endoscopic Myotomy of the Esophagus and StomachRecruitingNCT056022721 country
- Ultrasonography Guided Pneumoperitoneum for Laparoscopic Surgery in Morbidly Obese PatientsCompletedNCT06413264Not applicable1 country
- Hemodynamic Effects of Trendelenburg Position and Pneumoperitoneum in Urologic Robotic SurgeryCompletedNCT078485811 country
- Pneumoperitoneum Pressure and Lung Ultrasound AtelectasisCompletedNCT07609615Not applicable1 country
- Perioperative QT and QTc Changes in Laparoscopic and Open HysterectomyCompletedNCT078340601 country
- Optic Nerve Sheath Diameter Changes During Bariatric SurgeryCompletedNCT076625381 country
- Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy PatientsCompletedNCT07079514Phase 1/21 country
- VIMA vs TIVA and ONSD in Laparoscopic CholecystectomyCompletedNCT07786740Phase 41 country
- Paired Comparison of SVV and PVI AccuracyCompletedNCT072608901 country
- Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) TrialWithdrawnNCT04858438Not applicable1 country
- Effect of Recruitment Maneuver on Postoperative Atelectasis Assessed by Lung Ultrasound in Laparoscopic CholecystectomyCompletedNCT07324122Not applicable1 country
- Low vs Medium Pressure PneumoperitoneumCompletedNCT04949659Not applicable1 country
- "Comparison of of Volume-Controlled Ventilation and Pressure-Controlled Ventilation Modes in Laparoscopic Cholecystectomy"Active, not recruitingNCT07709039Not applicable1 country
- Effects of Standard and Modified Z-Trendelenburg Positions on Cerebral Oxygenation and Optic Nerve Sheath DiameterCompletedNCT076322871 country
- Transumbilical Versus Infraumbilical Pneumoperitoneum in Laparoscopic CholecystectomyCompletedNCT07601035Not applicable1 country
- Prospective Randomized Trial of Moderate vs Deep Neuromuscular Blockade During Laparoscopic Ventral Hernia RepairWithdrawnNCT03201744Not applicable1 country
- Electrocardiographic Changes in Cholecystectomy SurgeryCompletedNCT066514501 country
- The Validation of the Identification System of Fiber-optic Probe Optical Coherent Tomography Assisted Pneumoperitoneum CreationCompletedNCT074381321 country
- Optic Nerve Sheath Diameter Changes in Laparoscopic CholecystectomyCompletedNCT07162922Not applicable1 country
- Efficacy of Nebulized Dexmedetomidine on Blunting Hemodynamic Changes During Intubation and Pneumoperitoneum in Morbid Obese Patients During Laparoscopic Bariatric SurgeryCompletedNCT07054138Not applicable1 country
- Effect of Changes in Endotracheal Tube Cuff Pressure on Postoperative Pharyngolaryngeal Complications in Robotic SurgeryCompletedNCT072421441 country
- AI Assisted Detection of Chest X-RaysCompletedNCT060758361 country
- Ultrasound Assessment of Airway Edema During Laparoscopic CholecystectomyCompletedNCT07021482Not applicable1 country