Peripheral Nerve Injuries clinical trials
The registry lists 90 studies for Peripheral Nerve Injuries across more than 10 countries. 24 are recruiting or about to start. 68 of them are mainly about Peripheral Nerve Injuries (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Who runs them
Axogen Corporation (7) · Ruhr University of Bochum (3) · W. Dalton Dietrich (3) · Ukrainian Society of Regional Anesthesia and Pain Therapy (3) · University of Alberta (3) · University of Utah (2) · University of Sao Paulo (2) · Neuraptive Therapeutics Inc. (2)
What is being tested here
Drugs under test in Peripheral Nerve Injuries studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Mar 2027This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations. · Phase 3 · Neuraptive Therapeutics Inc.
- Dec 2026Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends · Axogen Corporation
- Dec 2026Effect of Ultrasound Guided PRP Injection on Post Trumatic Peripheral Nerve Regeneration. · Seham A. Elazab
- Dec 2026A Study to Expand the Use of Symani® Surgical System for Peripheral Nerve Repair · MMI (Medical Microinstruments, Inc.)
- Dec 2026Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System · Hacettepe University
- May 2027Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation · Ukrainian Society of Regional Anesthesia and Pain Therapy
- Jun 2027High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury · Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
- Jun 2027Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) · VM Therapeutics LLC
- Aug 2027Non-invasive Therapy to Drive Nerve Regeneration · University of Alberta
- Sep 2027Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI) · W. Dalton Dietrich
Who these studies take
Of the 18 Peripheral Nerve Injuries studies recruiting now, 7 (39%) set no upper age limit and 7 (39%) stop at 75 or younger. 2 (11%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (6%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (11%) | 2 (11%) |
| 18 | 18 (100%) | 18 (100%) |
| 30 | 17 (94%) | 17 (94%) |
| 40 | 17 (94%) | 17 (94%) |
| 50 | 16 (89%) | 16 (89%) |
| 65 | 15 (83%) | 15 (83%) |
| 75 | 11 (61%) | 11 (61%) |
| 85 | 8 (44%) | 8 (44%) |
Across all 90 studies, recruiting or not: 47% stop at 75 or younger and 36% at 65; 17% take children; 1% are for women only and 2% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Peripheral Nerve Injuries studies take
Of 26 interventional studies with no phase under Peripheral Nerve Injuries, half reached primary completion within 35 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 35 mo20–57 · 26 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
- Safety and Efficacy of NTX-001 Compared to SOC in Acute Single Peripheral Nerve InjuriesOct 15, 2026NCT04572906
Newly registered1
- Blast-related Regional Anaesthesia and Peripheral nerVe Injury EvaluationOct 19, 2026NCT07879508
Studies
Recruiting first, then most recently updated. Showing 50 of 90. Browse all 90 → or search them.
- Tesamorelin to Improve Functional Outcomes After Peripheral Nerve InjuryRecruitingNCT03150511Phase 21 country
- Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)RecruitingNCT07072468Phase 21 country
- Blast-related Regional Anaesthesia and Peripheral nerVe Injury EvaluationNot yet recruitingNCT07879508Not applicable
- Effect of Ultrasound Guided PRP Injection on Post Trumatic Peripheral Nerve Regeneration.RecruitingNCT07879092Not applicable1 country
- Nerve Blocks or Combat Trauma: What Drives Peripheral Nerve Injury?Not yet recruitingNCT07868133
- Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve ReconstructionRecruitingNCT07657182Phase 41 country
- This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.RecruitingNCT06616025Phase 31 country
- Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI)RecruitingNCT05541250Phase 11 country
- High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve InjuryRecruitingNCT07705490Not applicable1 country
- Continuous Observational Monitoring Program for Allay™ Hydrogel Cap Safety and Success StudyRecruitingNCT072469801 country
- A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve RepairRecruitingNCT06529835Not applicable1 country
- Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy AdultsRecruitingNCT07363395Phase 11 country
- Upper Extremity Functional Electrical Stimulation (FES) for Restoration of Upper Extremity Function After Spinal Cord Injury (SCI)RecruitingNCT06672458Not applicable1 country
- EMG-Triggered Electrical Stimulation After Median/Ulnar Nerve RepairsNot yet recruitingNCT07532499Not applicable
- Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring SystemNot yet recruitingNCT075220601 country
- Non-invasive Therapy to Drive Nerve RegenerationEnrolling by invitationNCT05848778Not applicable1 country
- A Study to Expand the Use of Symani® Surgical System for Peripheral Nerve RepairRecruitingNCT07084207Not applicable1 country
- 4-AP Peripheral Nerve Crossover TrialRecruitingNCT06003166Phase 21 country
- Effect of Nerve Stimulation on Sciatic Nerve Injury Pediatric PatientsRecruitingNCT06781060Not applicable1 country
- Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional StudyNot yet recruitingNCT06638008Not applicable
- Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve RepairRecruitingNCT03610763Not applicable1 country
- Experience and Feasibility of Methods for Early Sensory TrainingRecruitingNCT05611983Not applicable1 country
- Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral NeuropathyRecruitingNCT06071936Phase 31 country
- Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral NeuropathyRecruitingNCT06071988Phase 31 country
- Proximal Nerve Cryoablation Versus Perineuroma Cryoablation for Chronic Neuroma Pain After Combat-Related AmputationCompletedNCT07618689Not applicable1 country
- Safety and Efficacy of NTX-001 Compared to SOC in Acute Single Peripheral Nerve InjuriesCompletedNCT04572906Phase 21 country
- Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)Active, not recruitingNCT04789044Phase 21 country
- Promoting Healing of Injured Nerves With Electrical Stimulation TherapyCompletedNCT05884125Not applicable1 country
- Interhemispheric Connectivity and CompensationCompletedNCT05207878Not applicable1 country
- Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of FunctionCompletedNCT02359825Phase 11 country
- Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve EndsActive, not recruitingNCT04865679Not applicable1 country
- Electrical Stimulation to Enhance Peripheral Nerve RegenerationCompletedNCT02403661Not applicable1 country
- A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve InjuryCompletedNCT06091020Phase 26 countries
- High-Purity Type I Collagen Nerve Wrapping in Peripheral Nerve Procedures: A Prospective RegistryCompletedNCT07360730Not applicable1 country
- Mirror Therapy Integrated With Electrical Stimulation for Cortical ModulationsActive, not recruitingNCT06209801Not applicable1 country
- Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve ReconstructionActive, not recruitingNCT015266814 countries
- Mirror Therapy Combined With Contralaterally Controlled Functional Electrical Stimulation for Peripheral Nerve InjuryCompletedNCT06209632Not applicable1 country
- Autologous Human Schwann Cells in Peripheral Nerve RepairCompletedNCT03999424Phase 11 country
- Registry of Avive® Soft Tissue Membrane Utilization in Selected Applications of Acute Trauma of the Upper ExtremityTerminatedNCT039431341 country
- StimRouter Registry Clinical ProtocolCompletedNCT039136891 country
- Study of Nerve Repair and Reconstruction Associated With Major Extremity TraumaCompletedNCT027187681 country
- Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma PainCompletedNCT03940963Not applicable1 country
- TISSIUM's Nerve Coaptation Device First-in-Human Clinical TrialCompletedNCT04327154Not applicable1 country
- The Effect of Pre-operative Electrical Stimulation on Peripheral Nerve Regeneration.CompletedNCT03205124Phase 2/31 country
- Study of Nerve Reconstruction Using AVANCE in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate CancerCompletedNCT00953277Phase 41 country
- The Role of Ultrasonography in the Diagnosis of Double Crush SyndromeActive, not recruitingNCT065398711 country
- REINVENT Registry (Registry of the Nerve Gap Repair From Integra)TerminatedNCT053395941 country
- Surgical Treatment of Chronic Neuropathic PainTerminatedNCT042870751 country
- Virtual Reality in Hand Peripheral Nerve Injuries Effectiveness of Based Movement TherapyCompletedNCT05898568Not applicable1 country
- Polyethylene Glycol to Improve Sensation Following Digital Nerve LacerationWithdrawnNCT04270019Phase 1/2