Insulinoma clinical trials
The registry lists 62 studies for Insulinoma across more than 10 countries. 12 are recruiting or about to start. 16 of them are mainly about Insulinoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-20.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Cancer Institute (NCI) (8) · Peking Union Medical College Hospital (5) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3) · British Columbia Cancer Agency (3) · Rezolute (2) · Vanderbilt-Ingram Cancer Center (2) · Eastern Cooperative Oncology Group (2) · ECOG-ACRIN Cancer Research Group (2)
What is being tested here
Drugs under test in Insulinoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Fluorodopa F 18 | 2 | 0 | 2 |
| Ersodetug | 1 | 1 | 1 |
| Temozolomide | 0 | 0 | 3 |
| Everolimus | 0 | 0 | 3 |
| Capecitabine | 0 | 0 | 3 |
| Vatalanib | 0 | 0 | 2 |
| Bevacizumab | 0 | 1 | 2 |
| Octreotide | 0 | 0 | 2 |
| Motesanib diphosphate | 0 | 0 | 1 |
| Regorafenib | 0 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 8 · Antimetabolites 5 · Alkylating agents 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- Sep 2027A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism · Phase 3 · Rezolute
- Aug 2027Comparison of [68Ga]Ga-HBED-CC-PEG6-Exendin-4 and [68Ga]Ga-HBED-CC-Exendin-4 PET/CT for Insulinoma Localization · Peking Union Medical College Hospital
- Nov 2027Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related Disease · Tianjin Medical University
Who these studies take
Of the 10 Insulinoma studies recruiting now, 3 (30%) set no upper age limit and 4 (40%) stop at 75 or younger. 4 (40%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (30%) | 3 (30%) |
| 18 | 10 (100%) | 10 (100%) |
| 30 | 9 (90%) | 9 (90%) |
| 40 | 9 (90%) | 9 (90%) |
| 50 | 9 (90%) | 9 (90%) |
| 65 | 9 (90%) | 9 (90%) |
| 75 | 7 (70%) | 7 (70%) |
| 85 | 4 (40%) | 4 (40%) |
Across all 62 studies, recruiting or not: 13% stop at 75 or younger and 3% at 65; 19% take children; 0% are for women only and 0% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 62. Browse all 62 → or search them.
- Diagnosing and Treating Low Blood Sugar LevelsRecruitingNCT000012761 country
- Intermediate-Size Cohort EAP for Ersodetug in Patients With Inadequately Controlled Hypoglycemia Related to a TumorAvailableNCT072629701 country
- A Phase 3 Study of Ersodetug in Patients With Tumor HyperinsulinismRecruitingNCT06881992Phase 35 countries
- Comparison of [68Ga]Ga-HBED-CC-PEG6-Exendin-4 and [68Ga]Ga-HBED-CC-Exendin-4 PET/CT for Insulinoma LocalizationRecruitingNCT07808879Not applicable1 country
- Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related DiseaseRecruitingNCT067256931 country
- Safety and Efficacy of EUS-RFA in Pancreatic InsulinomaRecruitingNCT075850321 country
- 18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic HypoglycemiaAvailableNCT019161481 country
- Utility of 18FDOPA PET/MRI for Focal HyperinsulinismRecruitingNCT05088798Phase 21 country
- Endoscopic Ultrasound-guided Radiofrequency Ablation for Upper Gastrointestinal Tract LesionsRecruitingNCT072721871 country
- Fluorodopa F 18 in Congenital Hyperinsulinism and InsulinomaRecruitingNCT02021604Phase 11 country
- A Multi-center Study to Evaluate the Efficacy and Safety of Pancreatic Duct Stents Placement Before the Enucleation of Insulinoma Located in the Head and Neck of the Pancreas Near the Main Pancreatic DuctRecruitingNCT05523778Not applicable1 country
- The Clinical Application of 68Ga-NOTA-exendin-4 PET/CT in Detecting InsulinomaRecruitingNCT04979611Phase 11 country
- Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine TumorsCompletedNCT01824875Phase 21 country
- DOTATOC PET/CT for Imaging NET PatientsActive, not recruitingNCT035835281 country
- Clinical Study of 18F-Exendin-4 in InsulinomaCompletedNCT073404371 country
- EUS-RFA Versus Surgery for Pancreatic Insulinoma (ERASIN-RCT)Active, not recruitingNCT05735912Not applicable1 country
- Everolimus and Vatalanib in Treating Patients With Advanced Solid TumorsCompletedNCT00655655Phase 11 country
- Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine TumorsCompletedNCT01525082Phase 21 country
- CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive HypoglycaemiaTerminatedNCT04452396Not applicable1 country
- AMG 706 and Octreotide in Treating Patients With Low-Grade Neuroendocrine TumorsCompletedNCT00427349Phase 21 country
- Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With SurgeryTerminatedNCT02031536Phase 21 country
- Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine TumorsTerminatedNCT00227617Phase 2/31 country
- 177Lu-DOTATOC for the Treatment of Patients With Somatostatin Receptor Positive NETsWithdrawnNCT04915144Phase 21 country
- 18F-FDOPA PET in Neuroendocrine TumoursNo longer availableNCT024317151 country
- [68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma PatientsStatus unknownNCT05034783Early Phase 11 country
- Laser Tissue Welding - Distal Pancreatectomy Sealing StudyCompletedNCT03147768Phase 11 country
- Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine TumorsCompletedNCT02259725Phase 21 country
- 68Ga-NODAGA-exendin-4 PET/CT for Diagnostic Imaging in AHHCompletedNCT03189953Phase 1/2
- Pasireotide in Hyperinsulinemic HypoglycemiaWithdrawnNCT03053284Phase 2
- Blinded Resection in Case of the Pancreatic InsulinomaCompletedNCT04741152
- Pazopanib Hydrochloride in Treating Patients With Advanced Neuroendocrine CancerCompletedNCT00454363Phase 21 country
- Clinical Evaluation of 68Ga-NOTA-MAL-Cys39-exendin-4 Positron Emission Tomography in the Detection of InsulinomaStatus unknownNCT04185350Early Phase 11 country
- Application of Raw Corn Starch on Patients With InsulinomaStatus unknownNCT03930368Not applicable1 country
- Panobinostat & Bortezomib in Pancreatic Cancer Progressing on Gemcitabine TherapyTerminatedNCT01056601Phase 21 country
- Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine TumorWithdrawnNCT02831179Phase 1
- Doxorubicin Beads in Treating Patients With Unresectable Liver Metastases From Neuroendocrine TumorsTerminatedNCT00730483Not applicable1 country
- Dovitinib Lactate in Treating Patients With Pancreatic Neuroendocrine TumorsWithdrawnNCT02108782Phase 2
- Cinacalcet to Treat Familial Primary HyperparathyroidismCompletedNCT00325104Phase 31 country
- Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney CancerTerminatedNCT02273752Phase 21 country
- Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine CarcinomaCompletedNCT01204476Phase 11 country
- Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid TumorsCompletedNCT00049023Phase 11 country
- Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By SurgeryCompletedNCT00416767Phase 2
- Vatalanib and Octreotide in Treating Patients With Progressive Neuroendocrine TumorsWithdrawnNCT00227773Phase 2
- 68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of NesidioblastosisStatus unknownNCT02560376Early Phase 11 country
- Whole Body 111In-exendin-4 Imaging Study in Insulinoma PatientsCompletedNCT009370791 country
- Sorafenib Tosylate in Treating Patients With Progressive Metastatic Neuroendocrine TumorsCompletedNCT00131911Phase 21 country
- Indium In 111 Pentetreotide in Treating Patients With Refractory CancerTerminatedNCT00002947Phase 11 country
- EUS-guided Ethanol Ablation of an InsulinomaStatus unknownNCT02121366Not applicable1 country
- Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainCompletedNCT00538850Phase 31 country
- Disease-Specific Questionnaire in Assessing Quality of Life in Patients With Gastrointestinal-Related Neuroendocrine TumorsStatus unknownNCT0045437610 countries