Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: Pancreatic Neoplasms trials

The registry lists 48 Pancreatic Neoplasms studies with Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins as lead sponsor. 4 are open to participants now and 25 have results posted.

Early Phase 1 2Phase 1 12Phase 2 29No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic TumorsRecruitingNCT07360119Not applicable
• NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic CancerRecruitingNCT06941857Phase 2
• Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic CancerRecruitingNCT06782932Phase 1/2
• KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal CancerRecruitingNCT06411691Phase 1
• Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic CancerCompletedNCT05014776Phase 2Results posted
• Plerixafor and Cemiplimab in Metastatic Pancreatic CancerCompletedNCT04177810Phase 2Results posted
• Trial of Neoadjuvant and Adjuvant Nivolumab and BMS-813160 With or Without GVAX for Locally Advanced Pancreatic Ductal Adenocarcinomas.CompletedNCT03767582Phase 1/2Results posted
• A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic CancerCompletedNCT03535727Phase 1/2Results posted
• A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic AdenocarcinomaCompletedNCT03250273Phase 2Results posted
• Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic CancerCompletedNCT03190265Phase 2Results posted
• GVAX Pancreas Vaccine (With CY) in Combination With Nivolumab and SBRT for Patients With Borderline Resectable Pancreatic CancerCompletedNCT03161379Phase 2Results posted
• Epacadostat, Pembrolizumab, and CRS-207, With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas CancerCompletedNCT03006302Phase 2Results posted
• Study With CY, Pembrolizumab, GVAX Pancreas Vaccine, and SBRT in Patients With Locally Advanced Pancreatic CancerCompletedNCT02648282Phase 2Results posted
• FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic CancerCompletedNCT01896869Phase 2Results posted
• Trial to Improve Outcomes in Patients With Resected Pancreatic Cancer (Azacitidine)CompletedNCT01845805Phase 2Results posted
• Palliative Stereotactic Radiation for Pancreatic or Periampullary AdenocarcinomaCompletedNCT01781728Phase 2Results posted
• Pancreatic Tumor Cell Vaccine (GVAX), Cyclophosphamide, SBRT, and FOLFIRINOX in Patients With Resected Adenocarcinoma of the PancreasCompletedNCT01595321Phase 2Results posted
• Gemcitabine/Taxotere/Xeloda (GTX) With Cisplatin in Subjects With Metastatic Pancreatic CancerCompletedNCT01459614Phase 2Results posted
• Trial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic CancerCompletedNCT01296763Phase 1Results posted
• Boost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas CancerActive, not recruitingNCT01088789Phase 2Results posted
• Ipilimumab +/- Vaccine Therapy in Treating Patients With Locally Advanced, Unresectable or Metastatic Pancreatic CancerCompletedNCT00836407Phase 1Results posted
• Vaccine Therapy With or Without Cyclophosphamide in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Stage I or Stage II Pancreatic Cancer That Can Be Removed by SurgeryCompletedNCT00727441Phase 2Results posted
• Standard Pain Control or Intrathecal Therapy in Controlling Pain in Patients With Locally Advanced, Unresectable, or Metastatic Pancreatic CancerTerminatedNCT00660348Not applicableResults posted
• Sirolimus in Treating Patients With Advanced Pancreatic CancerCompletedNCT00499486Phase 2Results posted
• Adjuvant GVAX Vaccine Therapy in Patients With Pancreatic CancerCompletedNCT00389610Phase 2Results posted
• ChemoRT With Adjuvant Chemo in Pancreatic Cancer (TARCEVA)CompletedNCT00313560Phase 2Results posted
• Vaccine Therapy, Cyclophosphamide, and Cetuximab in Treating Patients With Metastatic or Locally Advanced Pancreatic CancerCompletedNCT00305760Phase 2Results posted
• Individualized Drug Treatment for Treating Patients With Pancreatic CancerTerminatedNCT00276744Phase 2Results posted
• Vaccine Therapy Combined With Adjuvant Chemoradiotherapy in Treating Patients With Resected Stage I or Stage II Adenocarcinoma (Cancer) of the PancreasCompletedNCT00084383Phase 2Results posted
• Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic AdenocarcinomaActive, not recruitingNCT05141513Phase 1
• Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic CancerActive, not recruitingNCT05013216Phase 1
• Breath-Hold Technique for Pancreatic Stereotactic Body Radiation Therapy (SBRT) PatientsTerminatedNCT04843306Not applicable
• Neoantigen-Targeted Vaccine Combined With Anti-PD-1 Antibody for Patients With Stage IV MMR-p Colon and Pancreatic Ductal CancerWithdrawnNCT04799431Phase 1
• Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.Active, not recruitingNCT04753879Phase 2
• Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic CancerActive, not recruitingNCT04117087Phase 1
• Selective Transvenous Chemoembolization of Primary Pancreatic TumorsWithdrawnNCT03865563Phase 1
• A Pilot Trial of Scrambler Therapy for Pain Associated With Pancreas CancerWithdrawnNCT03707444
• Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the PancreasActive, not recruitingNCT02451982Phase 2
• Integrating Palliative Care and Modern Palliative Care Tools Into the Care of Patients With Pancreas CancerWithdrawnNCT01784081
• Safety Study of Adjuvant Gemcitabine Started One Week After Laparoscopic Distal Pancreatectomy for AdenocarcinomaWithdrawnNCT01045941Phase 2
• Collecting and Storing Samples of Blood From Patients With Pancreatic Cancer and Healthy ParticipantsCompletedNCT00898482
• Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study)CompletedNCT00714701
• Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial CancerTerminatedNCT00499733Early Phase 1
• Making Decisions About Participating in a Cancer Clinical Trial for Patients With Stage II, Stage III, or Stage IV Pancreatic Cancer or Stage III or Stage IV Colon Cancer or Rectal CancerCompletedNCT00478010Not applicable
• Study of Mitomycin-C in Patients With Advanced or Recurrent Pancreatic Cancer With Mutated BRCA2 GeneWithdrawnNCT00386399Phase 2
• Safety Study to Determine the Appropriate Dose of Antibody Against Tumor Cells to Best Target Patients With Pancreatic Cancer.TerminatedNCT00364364Early Phase 1
• Capecitabine as Second-Line Therapy in Treating Patients With Stage IV Pancreatic Cancer Who Have the Thymidylate Synthase GeneCompletedNCT00303927Phase 2
• Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Cancer of the Pancreas That Cannot Be Removed by SurgeryCompletedNCT00003798Phase 1