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RecruitingNCT03001934Updated Sep 15, 2026

Super Chinese Nephrotic Syndrome Registration System (SUCCESS)

An observational study in Nephrotic Syndrome, sponsored by Sun Yat-sen University. Recruiting at 1 site in China. Open to participants aged 14 Years and older. Per ClinicalTrials.gov, last updated 2026-09-15.

Sponsored by Sun Yat-sen University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
5,000
Ages
14 Years and older
Sex
All
01

Study summary

The investigators are registering all nephrotic syndrome (NS) patients regardless of the primary causes and developing a NS database in China. Patients will be followed-up and both baseline and follow-up information will be recorded in the registration system. The treatment response, longitudinal changes of renal function, renal survival, patient survival, infection events and acute kidney injury etc, will be analyzed using the NS database.

Read the detailed description

The investigators are registering all NS patients regardless of the primary causes in China. Patients' demographic characteristics (including age, gender, height, weight, BMI, smoking, drinking, and education), clinical characteristics (including systolic blood pressure, diastolic blood pressure, primary cause of NS, and lab measurements of serum, urine), pathological characteristics, treatment and treatment response, complications and outcomes. Patients will be followed up, the demographic, clinical characteristics, treatment, lab tests of blood and urine and complications of patients will be collected and recorded at each visit. The investigators also record the outcome at each visit, such as treatment response, longitudinal changes of renal function, hospitalization, occurrence of infection or cardiovascular events etc. The outcomes will be analyzed using the NS database.

02

Conditions studied

  • Nephrotic Syndrome

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Keywords

  • Nephrotic syndrome
  • Treatment response
  • Renal function
03

Who can participate

Ages eligible
14 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Nephrotic syndrome patients

Inclusion criteria

  • Nephrotic syndrome patients regardless of the primary causes

Exclusion criteria

Exclusion Criteria:

  • No
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
5,000 participants (estimated)
Target follow-up
10 Years
Patient registry
Yes
Biospecimen retention
Samples with dna

Groups and cohorts

  • Nephrotic syndrome patients

    Patients diagnosis as nephrotic syndrome (NS)

    Other: No intervention

Interventions

  • OtherNo intervention

    Registration of all NS patients in the First Affiliated Hospital of Sun Yat-sen University and other hospitals which have signed the contract in China.

05

What researchers measure

Primary outcomes

  1. The patient survival in NS patients

    Time frame: 10 years

Secondary outcomes

  1. Renal survival in NS patients

    Renal survival including end stage renal disease, dialysis, renal transplantation

    Time frame: 10 years

  2. Longitudinal changes of renal function of NS patients

    Time frame: 10 years

  3. Treatment response of NS patients

    Time frame: 10 years

  4. Infection rate of NS patients

    Time frame: 10 years

06

Study locations

1 of 1 sites recruiting
  • The 1st Affiliated Hospital, Sun Yet-sen University
    Guangzhou, Guangdong 510080, China
    Recruiting
07

References and documents

Individual participant data

Plan to share: Yes

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03001934
Lead sponsor
Sun Yat-sen University
Responsible party
Xue Qing Yu (Professor, Sun Yat-sen University) — Principal investigator
First posted
Dec 23, 2016
Start date
Apr 2016
Primary completion
Dec 2029 (estimated)
Completion
Dec 2029 (estimated)
Last update
Sep 15, 2026

Study contacts

Xueqing Yu, M.D. & Ph.D
Contact
yuxq@mail.sysu.edu.cn
Naya Huang, M.D. & Ph.D
Contact
huangnaya@163.com

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

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