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Muscular Atrophy, Spinal clinical trials

The registry lists 282 studies for Muscular Atrophy, Spinal across more than 10 countries. 73 are recruiting or about to start. 204 of them are mainly about Muscular Atrophy, Spinal (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 2 narrower conditions too, such as Spinal Muscular Atrophies of Childhood: 361 studies, 94 open.

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Status

Completed
130
Recruiting
58
Active, not recruiting
32
Status unknown
24
Terminated
12
Not yet recruiting
11

Phase

Phase 2
40
Phase 3
26
Phase 1
24
Phase 4
8
Early Phase 1
3

Where

United States
121
Italy
41
France
39
Germany
37
United Kingdom
34
Canada
29

Who runs them

Biogen (27) · Hoffmann-La Roche (16) · Novartis Pharmaceuticals (14) · Columbia University (9) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (9) · University of Utah (6) · Institut de Myologie, France (5) · National Taiwan University Hospital (5)

What is being tested here

Drugs under test in Muscular Atrophy, Spinal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Nusinersen3719
Salanersen333
Apitegromab124
Adimanebart101
Anti-MuSK Agonistic Monoclonal Antibody ARGX-119101
Risdiplam0013
Onasemnogene abeparvovec045
Valproic Acid015
Carnitine013
Phenylbutyric acid003

Coming up

9phase 3 studies under way
30studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 58 Muscular Atrophy, Spinal studies recruiting now, 28 (48%) set no upper age limit and 27 (47%) stop at 75 or younger. 46 (79%) take children under 18. 1 (2%) are for women only and 1 (2%) for men only; 11 (19%) take healthy volunteers.

Recruiting studies that take each age, of 58
AgeWomenMen
1029 (50%)29 (50%)
1839 (67%)39 (67%)
3037 (64%)37 (64%)
4037 (64%)37 (64%)
5037 (64%)37 (64%)
6534 (59%)34 (59%)
7532 (55%)32 (55%)
8530 (52%)30 (52%)

Across all 282 studies, recruiting or not: 57% stop at 75 or younger and 52% at 65; 79% take children; 1% are for women only and 1% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Muscular Atrophy, Spinal studies take

Of 18 phase 3 interventional studies under Muscular Atrophy, Spinal, half reached primary completion within 33 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 234 mo25–42 · 15 studies——
Phase 333 mo24–63 · 18 studies——
Interventional, no phase27 mo17–51 · 57 studies—28 mo19–52 · 48 studies
Observational88 mo36–… · 58 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting2

Results posted1

Stopped1

Newly registered5

Studies

Recruiting first, then most recently updated. Showing 50 of 282. Browse all 282 → or search them.