Mouth Diseases clinical trials
The registry lists 99 studies for Mouth Diseases across more than 10 countries. 19 are recruiting or about to start. 41 of them are mainly about Mouth Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-16. Counting its 53 narrower conditions too, such as Periodontitis: 7,573 studies, 1,622 open.
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Who runs them
Al-Mustansiriyah University (4) · Cairo University (3) · University of Campinas, Brazil (3) · University of Copenhagen (2) · The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine (2) · CuraGen Corporation (2) · University of Baghdad (2) · National Institute of Dental and Craniofacial Research (NIDCR) (2)
What is being tested here
Drugs under test in Mouth Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Nov 2026Insomnia and Post-Dental Surgery Pain: A Prospective Study · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Nov 2026Effect of Apical Patency on Periapical Lesion Healing · Recep Tayyip Erdogan University
- Apr 2027SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography · University of Palermo
- Sep 2027Evaluation of Changes in Oral Health-related Quality of Life During the Treatment of Periodontitis. · University Hospital, Clermont-Ferrand
- Oct 2027Evaluation of Masticatory Performance in Patients With Periodontitis · University Hospital, Clermont-Ferrand
Who these studies take
Of the 12 Mouth Diseases studies recruiting now, 8 (67%) set no upper age limit and 2 (17%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 1 (8%) for men only; 4 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 8 (67%) | 9 (75%) |
| 30 | 8 (67%) | 9 (75%) |
| 40 | 8 (67%) | 9 (75%) |
| 50 | 8 (67%) | 9 (75%) |
| 65 | 9 (75%) | 10 (83%) |
| 75 | 9 (75%) | 10 (83%) |
| 85 | 9 (75%) | 9 (75%) |
Across all 99 studies, recruiting or not: 51% stop at 75 or younger and 39% at 65; 27% take children; 3% are for women only and 4% for men only; 43% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Mouth Diseases studies take
Of 21 interventional studies with no phase under Mouth Diseases, half reached primary completion within 9 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 9 mo7–27 · 21 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
- Evaluation of Masticatory Performance in Patients With PeriodontitisOct 16, 2026NCT07665489
Studies
Recruiting first, then most recently updated. Showing 50 of 99. Browse all 99 → or search them.
- Evaluation of Masticatory Performance in Patients With PeriodontitisRecruitingNCT076654891 country
- Evaluation of Changes in Oral Health-related Quality of Life During the Treatment of Periodontitis.Not yet recruitingNCT078680421 country
- Insomnia and Post-Dental Surgery Pain: A Prospective StudyRecruitingNCT077124321 country
- Discovery and Validation of Biomarkers for Periodontitis, Dental Caries and Oral Squamous Cell CarcinomaNot yet recruitingNCT077458031 country
- RetracTOR/ Retractor for Image Guided Trans-Oral SurgeryRecruitingNCT063815051 country
- Prevalence and Clinical Implications of HPV Infection in Male IBD PatientsRecruitingNCT059117501 country
- SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence TomographyRecruitingNCT063210031 country
- Role of Kefir Mouth Wash in Oral Health Status AmeliorationRecruitingNCT06900881Phase 2/31 country
- Oral Health in Adults: Social Gradients and Correlation With Cardiovascular HealthEnrolling by invitationNCT057584671 country
- Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.RecruitingNCT06882564Phase 31 country
- Effectiveness of MySmile App for Improving the Oral Health of Secondary School Children:Not yet recruitingNCT06381700Not applicable1 country
- Evaluation of the Galea-pericranium Flap in Reconstruction of Oral Cavity DefectsRecruitingNCT06714760Not applicable1 country
- Evaluation of Oral Potentially Malignant Disorders (OPMDs) with STRATICYTE™RecruitingNCT058537831 country
- Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway SurgeryRecruitingNCT06507202Phase 41 country
- Can a Low-threshold Check-up Motivate Older People to Schedule a Dental Visit?RecruitingNCT06341959Not applicable1 country
- Role of the Oral Microbiome & Mucosal Immunity in COVID-19 DiseaseRecruitingNCT052127661 country
- Assessment and Remediation of Oral DisordersNot yet recruitingNCT06046768Not applicable1 country
- Oral Health Related Quality of LifeNot yet recruitingNCT05923762
- Effectiveness and Retention of Pit and Fissure Sealants in Rural Setup: A School-based Clinical Trial in NepalEnrolling by invitationNCT058942001 country
- Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant DisordersActive, not recruitingNCT02790853Early Phase 11 country
- Effect of Apical Patency on Periapical Lesion HealingActive, not recruitingNCT07867314Not applicable1 country
- Identification of Oral Lesions Through an Autofluorescence SystemCompletedNCT05942794Not applicable1 country
- Individual Variability of Experimental Gingivitis ResponseCompletedNCT056564171 country
- Optical Sensor for Photodynamic Detection of Oral PathologyCompletedNCT00540774Not applicable1 country
- Chlorhexidine Plus Hyaluronic Acid Mouthwash in Surgical Wound Healing Following Third Molar SurgeryActive, not recruitingNCT05414253Not applicable1 country
- COMPARISON OF THE EFFICIENCY OF MANUAL SINGLE HEADED AND TRIPLE HEADED TOOTHBRUSHES IN REMOVING DENTAL PLAQUE AND USER EXPERIENCECompletedNCT07433374Not applicable1 country
- RCT on Effectiveness of Oral Health Preventive Programmes in School Children in UgandaSuspendedNCT06081868Not applicable1 country
- Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years OldCompletedNCT06888453Phase 11 country
- The Impact of Ginger Mouthwash on the Pregnant Women With Stress and GingivitisCompletedNCT06792812Phase 21 country
- Application of Salivary Biomarkers in Risk Assessment for Oral Diseases in Children With Type 1 DiabetesActive, not recruitingNCT069243721 country
- Covid-19 and Prevention of Malnutrition After Confinement by DentistsCompletedNCT043864601 country
- Evaluation of the Use of a Novel Oral Health Screening Instrument by Caregivers in Nursing HomesActive, not recruitingNCT06536322Not applicable1 country
- Turkish Version of Child-Friendly Oral Health QuestionnaireCompletedNCT065250901 country
- The Effect of Stress, Anxiety, and Depression Experienced by Pregnant Women on Sleep Bruxism and Oral HealthCompletedNCT06520241Not applicable1 country
- Levilactobacillus Brevis Oral HealthCompletedNCT06457724Not applicable1 country
- Oral Health in Patients Hospitalized Because of Ischemic StrokeCompletedNCT063328461 country
- An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria.CompletedNCT05540171Not applicable1 country
- Analysis of Root Coverage Stability.Active, not recruitingNCT054393821 country
- Oral Health-related Patterns of Food Selectivity in Dental PopulationsCompletedNCT061406541 country
- Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen PeroxideCompletedNCT05787600Phase 31 country
- Oral Endocannabinoids in People With Prediabetes and DiabetesStatus unknownNCT06040164
- Regular Antibacterial Photodynamic Therapy on Oral Hygiene in Elderly ResidentsCompletedNCT05853679Not applicable1 country
- Combination of Diclofenac Potassium and Propolis in the Therapy of Oral AphthosisCompletedNCT05413096Early Phase 11 country
- Clinical Efficiency of Xanthan Hydrogels Containing Local Anesthetics Encapsulated in Nanostructured Lipid CarriesCompletedNCT05912335Phase 11 country
- Effect of Different Cleaning Regimes on Biofilm Formation of Acrylic Based Removable Orthodontic ApplianceStatus unknownNCT05707221Not applicable1 country
- A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's SyndromeTerminatedNCT04035668Phase 212 countries
- Metagenome Resilience in Experimental GingivitisCompletedNCT053891241 country
- Oral Health and Vitamin D in Stroke PatientsCompletedNCT054183351 country
- The Efficacy and Safety of Chlorhexidine Gluconate Chip (PerioChip®) in Therapy of Peri-implantitisCompletedNCT02080403Phase 34 countries
- Effectiveness of an Optimal-Massive Intervention in Older Patients With DysphagiaStatus unknownNCT04581486Not applicable1 country