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Xerostomia clinical trials

The registry lists 286 studies for Xerostomia across more than 10 countries. 51 are recruiting or about to start. 153 of them are mainly about Xerostomia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02. Counting its narrower condition Sjogren's Syndrome too: 573 studies, 140 open.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
172
Status unknown
30
Recruiting
26
Not yet recruiting
23
Active, not recruiting
13
Terminated
11

Phase

Phase 2
52
Phase 1
25
Phase 3
16
Phase 4
13
Early Phase 1
5

Where

United States
88
Egypt
19
Spain
19
France
18
Brazil
13
Turkey
13

Who runs them

National Institute of Dental and Craniofacial Research (NIDCR) (12) · Ain Shams University (9) · Roxane Laboratories (6) · M.D. Anderson Cancer Center (5) · Rigshospitalet, Denmark (5) · University of Nove de Julho (5) · University of Wisconsin, Madison (4) · Hadassah Medical Organization (3)

What is being tested here

Drugs under test in Xerostomia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Pilocarpine1210
Tofacitinib102
Cisplatin102
Hydroxychloroquine101
Leflunomide101
Mycophenolic Acid101
Hibiscus sabdariffa101
Cevimeline004
Cetoquagene parvec002
Rebamipide002

Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open

Coming up

4phase 3 studies under way
20studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 26 Xerostomia studies recruiting now, 15 (58%) set no upper age limit and 7 (27%) stop at 75 or younger. 2 (8%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (19%) take healthy volunteers.

Recruiting studies that take each age, of 26
AgeWomenMen
101 (4%)1 (4%)
1820 (77%)20 (77%)
3024 (92%)24 (92%)
4024 (92%)24 (92%)
5024 (92%)24 (92%)
6526 (100%)26 (100%)
7522 (85%)22 (85%)
8518 (69%)18 (69%)

Across all 286 studies, recruiting or not: 23% stop at 75 or younger and 9% at 65; 12% take children; 4% are for women only and 0% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Xerostomia studies take

Of 101 interventional studies with no phase under Xerostomia, half reached primary completion within 13 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase13 mo4–33 · 101 studies—16 mo7–33 · 85 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 286. Browse all 286 → or search them.