Meibomian Gland Dysfunction clinical trials
The registry lists 172 studies for Meibomian Gland Dysfunction across more than 10 countries. 23 are recruiting or about to start. 103 of them are mainly about Meibomian Gland Dysfunction (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
University of the Incarnate Word (5) · Lumenis Be Ltd. (5) · Chulalongkorn University (5) · Yonsei University (5) · Aston University (4) · Azura Ophthalmics (4) · Sight Sciences, Inc. (3) · Tear Film Innovations, Inc. (3)
What is being tested here
Drugs under test in Meibomian Gland Dysfunction studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction · Varol TUNALI
- Dec 2026A Multi Center Evaluation of TearCare on Surgical Measurements Before Cataract Surgery · Cleveland Eye Clinic
- Dec 2026Treating Meibomian Gland Disease in a Pediatric Population · Illinois College of Optometry
- Dec 2026Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment · University of California, Berkeley
- Dec 2026Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy · Singapore National Eye Centre
- Feb 2027Autologous Serum Obtained by a Closed-Circuit Collection Device · GIANCARLO FATOBENE
- Feb 2027Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction · University of Alabama at Birmingham
- Jul 2027The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial · Zhongshan Ophthalmic Center, Sun Yat-sen University
- Aug 2027TearCare in Young Adults · University of Alabama at Birmingham
- Sep 2027Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD · Candela Corporation
Who these studies take
Of the 13 Meibomian Gland Dysfunction studies recruiting now, 10 (77%) set no upper age limit and 1 (8%) stop at 75 or younger. 1 (8%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (8%) | 1 (8%) |
| 18 | 10 (77%) | 10 (77%) |
| 30 | 11 (85%) | 11 (85%) |
| 40 | 11 (85%) | 11 (85%) |
| 50 | 13 (100%) | 13 (100%) |
| 65 | 13 (100%) | 13 (100%) |
| 75 | 13 (100%) | 13 (100%) |
| 85 | 11 (85%) | 11 (85%) |
Across all 172 studies, recruiting or not: 16% stop at 75 or younger and 10% at 65; 6% take children; 3% are for women only and 0% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Meibomian Gland Dysfunction studies take
Of 74 interventional studies with no phase under Meibomian Gland Dysfunction, half reached primary completion within 11 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 11 mo5–19 · 74 studies | 9 mo2–15 · 22 studies | 11 mo5–27 · 52 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- A Multi Center Evaluation of TearCare on Surgical Measurements Before Cataract SurgeryNov 10, 2026NCT07928986
Studies
Recruiting first, then most recently updated. Showing 50 of 172. Browse all 172 → or search them.
- Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland DysfunctionEnrolling by invitationNCT07453212Not applicable1 country
- A Multi Center Evaluation of TearCare on Surgical Measurements Before Cataract SurgeryRecruitingNCT079289861 country
- Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGDRecruitingNCT06220474Not applicable1 country
- TearCare in Young AdultsNot yet recruitingNCT07579156Not applicable1 country
- Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic PatientsNot yet recruitingNCT07810569
- The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled TrialNot yet recruitingNCT07633938Not applicable1 country
- Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland DysfunctionRecruitingNCT07224529Phase 41 country
- Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye TreatmentRecruitingNCT07606625Phase 41 country
- Blink Reminders and Meibomian Gland Loss in Digital Screen UsersNot yet recruitingNCT07430137Not applicable
- Photobiomodulation With REd vs BluE Light (REBEL)RecruitingNCT06371300Not applicable2 countries
- Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light TherapyRecruitingNCT073297121 country
- Treating Meibomian Gland Disease in a Pediatric PopulationEnrolling by invitationNCT07229001Not applicable1 country
- Low Level Light Therapy & Skin PigmentationRecruitingNCT07173530Not applicable1 country
- The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative PeriodRecruitingNCT055497131 country
- Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry EyeNot yet recruitingNCT06686368Phase 4
- Efficacy of Adjunctive Low-Level Light Therapy to Intense Pulsed Light for Meibomian Gland DysfunctionRecruitingNCT06468930Not applicable1 country
- Single Lipiflow Treatment to Reduce Pharmacologic Burden in DEDEnrolling by invitationNCT06542276Not applicable1 country
- iTear Single-center, Open-label, Single-arm StudyNot yet recruitingNCT06525961Phase 41 country
- PET-CT Imaging Features of Meibomian GlandsRecruitingNCT063248901 country
- Efficacy and Safety of Topical Hydrocortisone on Signs and Symptoms of Dry Eye Associated to Meibomian Gland DysfunctionRecruitingNCT05159284Phase 41 country
- Function and Morphological Characteristics of Meibomian Gland in Patients With Renal AnemiaRecruitingNCT06287879Not applicable1 country
- BroadBand Light for the Treatment of Dry Eye DiseaseNot yet recruitingNCT06174064Not applicable
- To Evaluate the Efficacy of Diquafosol Sodium in the Treatment of MGD in Different Treatment PatternRecruitingNCT05383612Not applicable1 country
- Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGDActive, not recruitingNCT06064071Not applicable2 countries
- Autologous Serum Obtained by a Closed-Circuit Collection DeviceActive, not recruitingNCT07014059Phase 21 country
- Effect of a Dietary Supplement on Gut Microbiota and Ocular Surface Outcomes in Dry Eye DiseaseCompletedNCT07148271Not applicable1 country
- Effect of Oral Isotretinoin on Ocular Surface and Meibomian GlandsCompletedNCT07753811Not applicable1 country
- Efficacy and Safety of Thermic Devices in the Treatment of Meibomian Gland DysfunctionCompletedNCT03767530Not applicable1 country
- Effectiveness of Low Level Light Therapy and Intense Pulse Light on Mite Count as Adjuntive Therapies in Demodex Blepharitis Using Artificial Intelligent Program (Ai-Demodex)CompletedNCT07169461Not applicable1 country
- Intense Regulated Pulsed Light Vs Standard of Care for the Treatment of Meibomian Gland DysfunctionWithdrawnNCT04920396Not applicable1 country
- TearCare MGX™ System With and Without Warming HoldCompletedNCT07365735Not applicable1 country
- Meibomian Gland Changes in Ocular Prosthesis UsersCompletedNCT076219521 country
- Comparative Effects of USB-Powered Warm Compress and Self-Heating Eye Mask in the Management of Meibomian Gland DysfunctionCompletedNCT07618169Not applicable1 country
- Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland DysfunctionCompletedNCT06483750Not applicable1 country
- Vectored Thermal Pulsation, Intense Pulsed Light, and Eyelid Warm Compress Therapies for MGDCompletedNCT05577910Not applicable1 country
- Mechanisms of Light-based Therapies for Dry Eye DiseaseCompletedNCT06004895Not applicable1 country
- Effect of Micropulse Laser on Dry Eye Disease Due to Meibomian Gland DysfunctionCompletedNCT04425551Not applicable1 country
- Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Cataract SurgeryCompletedNCT07067294Not applicable1 country
- Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)CompletedNCT04795752Not applicable1 country
- Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGDCompletedNCT05454956Phase 21 country
- TearCare System to Treat Dry Eye DiseaseCompletedNCT03857919Not applicable1 country
- Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Femto-Lasik SurgeryCompletedNCT07181668Not applicable1 country
- Effect of Topical Azithromycin on Tear Film Thickness in Patients With Meibomian Gland DysfunctionCompletedNCT03162497Phase 41 country
- Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment StructuresCompletedNCT03461978Not applicable1 country
- The Efficacy of an Ocular Emulsion in Meibomian Gland DysfunctionCompletedNCT01207752Not applicable1 country
- The Effect of Gland Expression on the Regeneration of Meibomian GlandCompletedNCT06163105Not applicable1 country
- to Evaluate the Effectiveness and Safety of the Tixel® , VS LipiFlow® in the Treatment of Meibomian Gland DysfunctionCompletedNCT05162261Not applicable1 country
- Treatment Effect of Intense Pulsed Light and Thermal Pulsation Therapy on Meibomian Gland Dysfunction-associated Dry Eye Disease: a Randomized TrialCompletedNCT06745089Not applicable1 country
- Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland DisfunctionCompletedNCT04889950Not applicable1 country
- Comparison Between Continuous and Pulsed Oral Doxycycline Treatment Protocols for Refractory Meibomian Gland DysfunctionCompletedNCT065200071 country