Mandibular Fractures clinical trials
The registry lists 91 studies for Mandibular Fractures across more than 10 countries. 24 are recruiting or about to start. 85 of them are mainly about Mandibular Fractures (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
Cairo University (20) · Alexandria University (7) · Suez Canal University (6) · Mansoura University (4) · Hams Hamed Abdelrahman (4) · Stryker Craniomaxillofacial (3) · Fayoum University (3) · Tanta University (3)
What is being tested here
Drugs under test in Mandibular Fractures studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Platelet rich plasma | 1 | 0 | 1 |
| Dexamethasone | 1 | 0 | 1 |
| Methylprednisolone | 1 | 0 | 1 |
| Bupivacaine | 1 | 0 | 1 |
| Ascorbic Acid | 0 | 0 | 1 |
| Amoxicillin | 0 | 0 | 1 |
| Clavulanic Acid | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jun 2027The MANTRA Trial (MANdibular TRauma and Antibiotic Use) · Phase 3 · East Lancashire Hospitals NHS Trust
- Nov 2026Safety-zone Approach and Facial Nerve Preservation in Transbuccal-accessed Fixation of Mandibular Fractures · Delta University for Science and Technology
- Nov 2026Platelet-Rich Plasma for Bone Healing in Maxillary and Mandibular Fractures · CMH Lahore Medical College and Institute of Dentistry
- Nov 2026Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures · Nishtar Medical University
- Dec 20263D Printed Models for Mandibular Fracture Repair · University of Cincinnati
- Dec 2026Inter Flex Three Dimensional Plate in Management of Mandibular Fracture RCT · Suez Canal University
- Feb 2027Effect of Adipose Tissue Derived Autologous Mesenchymal Stem Cell Concentrate on Bone Quality in Mandibular Fracture Healing. · Cairo University
- Feb 2027Erich Arch Bars, IMF Screws and Hybrid Arch Bars in the Management of Mandibular Fractures · Mansoura University
- Feb 2027Comparing Bone Healing in Jaw Fractures Fixed With Herbert Screws Versus 3D Miniplates · Cairo University
- Feb 2027Evaluation of Condylar Position After Anterior Mandibular Fracture Fixation Using Plates Versus Headless Compression Screws · Cairo University
Who these studies take
Of the 11 Mandibular Fractures studies recruiting now, 2 (18%) set no upper age limit and 9 (82%) stop at 75 or younger. 1 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (18%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (9%) | 1 (9%) |
| 18 | 8 (73%) | 8 (73%) |
| 30 | 10 (91%) | 10 (91%) |
| 40 | 10 (91%) | 10 (91%) |
| 50 | 8 (73%) | 8 (73%) |
| 65 | 2 (18%) | 2 (18%) |
| 75 | 2 (18%) | 2 (18%) |
| 85 | 2 (18%) | 2 (18%) |
Across all 91 studies, recruiting or not: 56% stop at 75 or younger and 49% at 65; 31% take children; 0% are for women only and 1% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Mandibular Fractures studies take
Of 38 interventional studies with no phase under Mandibular Fractures, half reached primary completion within 13 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 13 mo9–24 · 38 studies | — | 13 mo9–24 · 38 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered3
- Platelet-Rich Plasma for Bone Healing in Maxillary and Mandibular FracturesNov 10, 2026NCT07930026
- Optimized Osteosynthesis: Bone Mineral Density Recovery in Mandibular Body Fractures Using Patient-Specific Versus Conventional PlatesOct 29, 2026NCT07904897
- Z-Shaped Versus Conventional Miniplates for Mandibular FracturesOct 28, 2026NCT07901686
Studies
Recruiting first, then most recently updated. Showing 50 of 91. Browse all 91 → or search them.
- Platelet-Rich Plasma for Bone Healing in Maxillary and Mandibular FracturesRecruitingNCT07930026Not applicable1 country
- Optimized Osteosynthesis: Bone Mineral Density Recovery in Mandibular Body Fractures Using Patient-Specific Versus Conventional PlatesRecruitingNCT07904897Not applicable1 country
- Occlusal Assessment of Pediatric Mandibular Fractures Managed by 3D-Printed Acrylic Occlusal Cap Splint: A Case SeriesRecruitingNCT07515937Not applicable1 country
- Custom-Made Titanium Plates Versus Custom-Made Polyether Ether Ketone (PEEK) PlatesRecruitingNCT07850570Not applicable1 country
- Virtual Surgical Planning and Preoperative Plate Bending for Maxillofacial FracturesNot yet recruitingNCT07856589Not applicable1 country
- Epidemiological and Statistical Study of Facial Traumatic Fractures at Assiut University Trauma HospitalNot yet recruitingNCT07827209
- Comparing Bone Healing in Jaw Fractures Fixed With Herbert Screws Versus 3D MiniplatesNot yet recruitingNCT07826416Not applicable
- Evaluation of Condylar Position After Anterior Mandibular Fracture Fixation Using Plates Versus Headless Compression ScrewsNot yet recruitingNCT07826403Not applicable
- Erich Arch Bars, IMF Screws and Hybrid Arch Bars in the Management of Mandibular FracturesRecruitingNCT07153120Not applicable1 country
- Safety-zone Approach and Facial Nerve Preservation in Transbuccal-accessed Fixation of Mandibular FracturesRecruitingNCT07807813Not applicable1 country
- Effect of Adipose Tissue Derived Autologous Mesenchymal Stem Cell Concentrate on Bone Quality in Mandibular Fracture Healing.Not yet recruitingNCT07671183Not applicable
- Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis FracturesRecruitingNCT07208799Phase 21 country
- 3D Custom Plate vs. Standard Titanium Plates for Mandibular Sub-condylar Fractures FixationNot yet recruitingNCT06978530Not applicable
- The MANTRA Trial (MANdibular TRauma and Antibiotic Use)RecruitingNCT05964140Phase 31 country
- Inter Flex Three Dimensional Plate in Management of Mandibular Fracture RCTRecruitingNCT07263893Not applicable1 country
- Sagittal Split Plate Versus Two Miniplates in the Treatment of Mandibular Angle FracturesRecruitingNCT07103590Not applicable1 country
- Multi-Institutional IMPACT ValidationEnrolling by invitationNCT068508571 country
- Finite Element and z Shap Mini Plate With Lingual ExtensionNot yet recruitingNCT06899568Not applicable
- z Mini-plate With Lingual Extension Versus Conventional 2 Mini PlatesNot yet recruitingNCT06898710Not applicable
- Accuracy of Computer Guided Screw Holes Locating Guide and Patient Specific Champy Plate vs Conventional Champy Plate Osteosynthesis in Management of Mandibular Angle Fracture: Randomized Controlled TrialNot yet recruitingNCT06838377Not applicable1 country
- Approaches for Open Reduction and Internal Fixation of Mandibular Condylar FractureNot yet recruitingNCT06333197Not applicable
- Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort StudyNot yet recruitingNCT06349135
- Fracture Pattern Following Bilateral Sagittal Split Osteotomy With or Without Impacted Third MolarsNot yet recruitingNCT06338982Not applicable1 country
- Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture SurgeryRecruitingNCT06243263Phase 41 country
- Evaluation Of New Shape of 3D Bone Plate in the Treatment of Posterior Mandibular FracturesCompletedNCT07929896Not applicable1 country
- Z-Shaped Versus Conventional Miniplates for Mandibular FracturesCompletedNCT07901686Not applicable1 country
- Fixation of Mandibular Angle Fracture Using 3D Titanium Miniplate Versus Standard Two Plate FixationActive, not recruitingNCT07574554Not applicable1 country
- Clinical and Radiographic Study of Erich Arch Bar Versus Embrasure Wire for Intermaxillary Fixation in Management of Mandibular FracturesCompletedNCT07860853Not applicable1 country
- Modified 3d Rectangular Grid Plate for Fixation of Anterior and Body Mandibular FracturesCompletedNCT07590401Not applicable1 country
- Clinical and Radiographical Assessment of Patients With Sub-condylar Fracture Using Polyetheretherketone (PEEK) Trapezoidal Plates Versus Titanium Trapezoidal PlatesCompletedNCT06940115Not applicable1 country
- 3D Printed Models for Mandibular Fracture RepairActive, not recruitingNCT05733221Not applicable1 country
- Evaluation of Pin Buckle Bone Plates for Management of Anterior Mandibular FracturesCompletedNCT07736430Not applicable1 country
- Stryker's Surgeon iD Mandible Reconstruction Plates: A Retrospective Post Market Follow UpCompletedNCT072219162 countries
- Facial iD Customized Mandible Reconstruction PlatesCompletedNCT072457581 country
- Stryker Facial iD Universal Plate Configurator: A Retrospective Post Market Follow UpActive, not recruitingNCT072458101 country
- Comparative Evaluation of 3D-printed (PEEK) Plates Versus Titanium 3D Plate for Fracture Fixation at the Mandibular AngleCompletedNCT07520227Not applicable1 country
- CAD/CAM Angle Fracture Reduction/Plate Guide and Customized 3D Grid Plate Versus Champy's TechniqueCompletedNCT06392204Not applicable1 country
- Precision of Patient Specific 3D Printed Occlusal Stent, Surgical Guide, and Patient Specific Titanium Plates in Management of Mandibular Fracture (Case Series)CompletedNCT074997261 country
- Evaluation of the Accuracy of 3d Printed Reduction Guide in Treatment of Mandibular Fractures Using Two Different Methods of Virtual PlanningCompletedNCT07385924Phase 41 country
- Single Locking Miniplates Versus Double Non-Locking Miniplates in Anterior Mandibular FractureCompletedNCT06938438Not applicable1 country
- Radiographic and Clinical Evaluation of Three-Dimensional Delta Plate in Internal Fixation of Mandibular Sub-condylar Fractures.CompletedNCT07311239Not applicable1 country
- Evaluation of Accuracy of Patient-Specific Plate for Reduction and Fixation of Mandibular Angle FractureCompletedNCT07231042Not applicable1 country
- Comparison of the Post-operative Efficacy of Arch Bar With Single Plate and Two Plate Fixation in Mandibular Parasymphsis Fracture.CompletedNCT06895174Not applicable1 country
- Evaluation of Modified Omega Plate in the Management of Mandibular Fractures Compared With Conventional FixationCompletedNCT07206134Not applicable1 country
- Evaluation of Z-shaped Bone Plates in Management of Mandibular FracturesActive, not recruitingNCT07184762Not applicable1 country
- Focused Registry to Collect Clinical Data on the MatrixWAVE SystemCompletedNCT034053892 countries
- Aetiology and Pattern of 122 Patients With Mandibular Condylar FractureCompletedNCT070998331 country
- Customized z Shaped Miniplate Versus Standard 2 Miniplates for Fixation of Parasymphyseal/Body Mandibular FracturesCompletedNCT07094867Not applicable1 country
- Fixation of Fractures at Anterior Transition Zone Using Three Different Miniplates ConfigurationsCompletedNCT07058597Not applicable1 country
- T-prf Versus T-prf and Low-level Laser Stimulation on Bone Healing at Posterior Mandibular FracturesCompletedNCT06970379Not applicable1 country