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Active, not recruitingNCT07245810UPCUpdated Apr 22, 2026

Stryker Facial iD Universal Plate Configurator: A Retrospective Post Market Follow Up

An observational study in Mandibular Fractures, Facial Fracture and Maxilla Fracture, sponsored by Stryker Craniomaxillofacial. Active, not recruiting at 2 sites in United States. Per ClinicalTrials.gov, last updated 2026-04-22.

Sponsored by Stryker Craniomaxillofacial · Observational

Study type
Observational
Model
Other
Time perspective
Retrospective
Enrollment
726
Sex
All
01

Study summary

A retrospective post market follow up to confirm safety and performance of Stryker's Facial iD Universal Plate Configurator (UPC) implants in the clinical setting. The study is performed to confirm the product's performance and safety by systematically collecting clinical data on its use.

Read the detailed description

This is a retrospective non-interventional post-market follow up aiming at confirming safety and performance of Stryker's Facial iD UPC plating system when used in the clinical setting. This study will include patients who have previously undergone a surgical procedure involving the Study Device, with surgical outcomes evaluated retrospectively. Based on a non-inferiority study power calculation a minimum of 80 patients will be enrolled in the study. Additional patients may be enrolled up to 800 subjects depending on site enrolment rate and patient availability. Up to 3 investigational sites within the United States will participate in this study. The primary outcome parameter evaluating successful fixation or reconstruction of the midface without the need for unplanned revision surgery will be evaluated at all available follow-up timepoints of the included patients.

02

Conditions studied

  • Mandibular Fractures
  • Facial Fracture
  • Maxilla Fracture
  • Orthognathic Surgical Procedures

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Keywords

  • Orthognathic Surgery
  • Mandibular Reconstruction
  • Mandibular Fractures
  • Mandibular Reconstruction* / Methods
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Eligible patients will be identified as having had a surgical procedure involving the Subject Device.

Inclusion criteria

  1. Patients who received a Stryker UPC plate for osteotomy, stabilization and rigid fixation of maxillofacial fractures or reconstruction as per routine clinical practice
  2. Patients for whom data on the primary outcome variable is available.

Exclusion criteria

Exclusion Criteria:

  1. Patients with non-reducible and unstable fractures at the time of surgery
  2. Patients with fractures of a severely atrophic mandible at the time of surgery
  3. Patients with active local infections at the time of surgery
  4. Patients with metal allergies and/or foreign body sensitivity at the time of surgery
  5. Patients with limited blood supply or insufficient quality or quantity of bone at the time of surgery
  6. Potentially non-compliant patients who are unwilling or incapable of following postoperative care instructions
04

Study design

Observational model
Other
Time perspective
Retrospective
Enrollment
726 participants (estimated)
Patient registry
No

Interventions

  • DeviceOrthognatic surgery, Reconstructive maxillofacial surgery, Mandible and maxillofacial trauma surgery

    Osteotomy, Mandible and Maxillofacial reconstruction, Orthognathic surgery

05

What researchers measure

Primary outcomes

  1. Successful fixation or reconstruction of the midface without the need for unplanned revision surgery.

    Assessed by reviewing adverse events in patient medical charts at time point after surgery. Used to document whether an unplanned revision surgery was required or not for patients.

    Time frame: Data collected at a single time point per patient in the course of 18 months.

Secondary outcomes

  1. Infection rate

    Determined by adverse events reported from patient medical charts.

    Time frame: Data collected at time points from patient medical charts in the course of 18 months.

  2. Intraoperative complications

    Determined by adverse events reported from patient medical charts.

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  3. Postoperative complications

    Determined by adverse events reported from patient medical charts.

    Time frame: Data collected at time points per patient in the course of 18 months.

  4. Any known adverse events

    Determined by adverse events reported from patient medical charts.

    Time frame: Data collected at time points per patient in the course of 18 months.

  5. Plate failure

    Determined by adverse events reported from patient medical charts.

    Time frame: Data collected at time points point per patient in the course of 18 months.

  6. Satisfactory occlusion achieved after additional orthodontic treatment

    Data reported in patient medical charts

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  7. Time to return to solid food/normal diet

    Time for patient to return to solid food/normal diet post operation (dd)

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  8. Hospitalization time; ICU and normal ward

    Time the patient was hospitalized post procedure (dd:hh)

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  9. EuroQol-5 Domain Questionnaire (if available)

    A descriptive system and a visual analogue scale (VAS). The descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, each with three to five levels of severity. The VAS provides a subjective rating of overall health on a scale from 0 to 100 (higher is better)).

    Time frame: Data collected at time points per patient in the course of 18 months.

  10. Facial Appearance, Quality of Life, and Satisfaction Questionnaire (if available)

    40 independently functioning scales and checklists. Multiple independent scales, each with a 0-100 score, where higher scores indicate better outcomes. Scores are calculated by summing responses on a 4-point Likert scale (e.g., strongly disagree to strongly agree), which are then converted to the 0-100 range. Each scale measures a specific aspect of facial appearance, quality of life, or adverse effects and cannot be summed into a single total score.

    Time frame: Data collected at time points per patient in the course of 18 months.

  11. 12-Item Short Form Health Survey (SF-12)

    12 items grouped and scored to produce two separate summary scores: the Physical Component Summary (PCS-12) and the Mental Component Summary (MCS-12). The scale is transformed to a 0-100 range with higher scores indicating better health.

    Time frame: Data collected at time points per patient in the course of 18 months.

Other outcomes

  1. Primary indication for the surgery / diagnosis

    Diagnosis collected from patient medical charts.

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  2. Max follow-up time

    Maximum post operative follow up time for patients within standard of care. Reported in patient medical charts during hospital follow up visits.

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  3. Surgical approach

    Surgical approach taken for the procedure. Including: transoral; intraoral; maxillary vestibular approach; transbuccal; submandibular; preauricular; other

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  4. Medical conditions

    Underlying medical conditions and medication that may be related to the device or primary outcome.

    Time frame: Data collected at time points point per patient in the course of 18 months.

  5. Localization of the defect

    Area to treated by the device: mandibular ramus; mandibular body; mandibular condyle; parasymphysis; paramedian; Le Fort I; Le Fort II; Le Fort III; others

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  6. Post operative maxillo-mandibular fixation

    For patients that receive maxillo-mandibular fixation post operation the length of time after surgery the fixation procedure took place (days).

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  7. Patient Radiation Exposure

    Exposure of patient to radiation therapy within 12 months around the surgery date recorded in patient medical charts (number and type of radiation procedures performed). Radiation therapy performed on the anatomical area treated with the device. Any postoperative radiation therapy recorded in patient medical charts.

    Time frame: Data collected at time points per patient in the course of 18 months.

  8. Sterilization method used

    Sterilization method used for the device. Qualitative responses from site.

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  9. Fixation system used

    System used to fix the device during the procedure. Stryker Universal CMF screws; others

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  10. Tightening of screws

    Tools used to fix the device during the procedure. Response options include : Manual and electric screw driver

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  11. Orthognathic cases

    Usage of splints in orthognathic cases.

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  12. Year smoking was stopped

    Year smoking was stopped (YYYY)

    Time frame: Data collected at time points per patient in the course of 18 months.

  13. Smoking frequency

    The frequency of exposure to smoking during periods of smoking (average number of cigarettes per day).

    Time frame: Data collected at time points per patient in the course of 18 month

  14. Smoking duration

    Duration of smoking (pack years)

    Time frame: Data collected at time points per patient in the course of 18 month

  15. Years of active smoking

    Total number of years active smoker (YY)

    Time frame: Data collected at time points per patient in the course of 18 month

  16. Patient weight

    Weight (kg, lb)

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  17. Patient height

    Height (cm, feet, inches)

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  18. Patient age

    Age (years)

    Time frame: Data collected at a single time point per patient in the course of 18 months.

  19. Gender

    Responses: Male, Female, undifferentiated, unknown

    Time frame: Data collected at a single time point per patient in the course of 18 months

06

Study locations

2 sites
  • New York Center for Orthognathic and Maxillofacial Surgery
    New York, New York 10022, United States
  • New York Center for Orthognathic and Maxillofacial Surgery, Lake Success, New York
    New York, New York 11042, United States
07

References and documents

08

Registry details

Key details

Study ID
NCT07245810
Lead sponsor
Stryker Craniomaxillofacial
Responsible party
Sponsor
First posted
Nov 24, 2025
Start date
Nov 18, 2024
Primary completion
May 31, 2026 (estimated)
Completion
May 31, 2026 (estimated)
Last update
Apr 22, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
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