An interventional study of Adipose tissue derived mesenchymal stem cells concentrate application in addition to the open reduction and internal fixation. and Open reduction and internal fixation in Mandible Fracture, sponsored by Cairo University. Not yet recruiting. Open to participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-06-29.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Among 20 studies in Mandibular Fractures by Cairo University — 6 open to participants now, 7 under way, none of them phase 3. Mandibular Fractures · Cairo University.
Among the 20 studies in Mandibular Fractures by Cairo University, this one is the 9th largest by planned enrollment of the 18 interventional ones, is one of 5 that started in 2026, is one of 18 with no phase, and was the 17th registered.
91 studies on the registry are indexed under Mandibular Fractures; 24 are open to participants now.
This study's planned enrollment of 20 is close to the median of 21 across 72 interventional studies indexed under Mandibular Fractures.
Browse Mandibular Fractures studies →6 of the 20 studies in Mandibular Fractures by Cairo University are open now, in 1 country. Each count lists the studies.
Of the 11 Mandibular Fractures studies recruiting now, 2 (18%) set no upper age limit and 9 (82%) stop at 75 or younger; 1 take children under 18; 2 take healthy volunteers.
This study: 18 Years to 40 Years · all sexes · no healthy volunteers.
The full table on the hub →20 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 5 started in 2026.
Median enrollment 20 across the 18 interventional studies, 183 across the 2 observational. Of the 4 that completed or were terminated, 0 (0%) have results posted.
Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
5 of the studies in Mandibular Fractures by Cairo University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07826416Cairo UniversityComparing Bone Healing in Jaw Fractures Fixed With Herbert Screws Versus 3D Miniplates | 2027-02 |
| NCT07826403Cairo UniversityEvaluation of Condylar Position After Anterior Mandibular Fracture Fixation Using Plates Versus Headless Compression Screws | 2027-02 |
| NCT07671183Cairo UniversityEffect of Adipose Tissue Derived Autologous Mesenchymal Stem Cell Concentrate on Bone Quality in Mandibular Fracture Healing. | 2027-02 |
| NCT07515937Cairo UniversityOcclusal Assessment of Pediatric Mandibular Fractures Managed by 3D-Printed Acrylic Occlusal Cap Splint: A Case Series | 2027-07 |
| NCT07904897Cairo UniversityOptimized Osteosynthesis: Bone Mineral Density Recovery in Mandibular Body Fractures Using Patient-Specific Versus Conventional Plates | 2027-11 |
Among the 20 studies in Mandibular Fractures by Cairo University, from their registry updates:
Participants will:
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
10 patients with mandibular fracture will be treated by application of adipose tissue derived MSCs concentrate on fracture line before and following fixation with titanium plates and screws.
Procedure: Adipose tissue derived mesenchymal stem cells concentrate application in addition to the open reduction and internal fixation.
10 patients with mandibular fracture will be treated by open reduction and internal fixation with titanium plates and screws.
Procedure: Open reduction and internal fixation
Abdominal fat liposuction will be carried out, microfragmentation of adipose tissue will be performed. Then the filtrate containing mesenchymal stem cells concentrate will be applied to the fracture line before and following fixation with titanium plates and screws .
Open reduction and internal fixation of fracture line with titanium plates and screws
Bone density
Assessment of bone density at fracture healing site by CBCT
Time frame: 3 months
Soft tissue dehiscence
Detection of soft tissue dehiscence occurrence (Binary: Yes/ No)
Time frame: 3 month
Bleeding
Detection of bleeding occurrence (Binary: Yes/ No)
Time frame: 3 months
Infection
Detection of Infection occurrence (Binary: Yes/ No)
Time frame: 3 months
Malocclusion
Detection of malocclusion occurrence (Binary: Yes/ No)
Time frame: 3 months
No study locations are listed for this record.
Plan to share: Yes
Supporting information: Study protocol, Statistical analysis plan, Informed consent form, Clinical study report, Analytic code
Start is estimated for Jul 2026; primary completion for Feb 2027, 7 months later.
Of 38 non-industry interventional studies with no phase under Mandibular Fractures, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 24. This study's planned 7 months is below that.
Counting every sponsor, half of 38 studies reached it within 13 months; a quarter within 9 and three quarters within 24.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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